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Real-life couple Rhea Butcher and Cameron Esposito make a perfect pair in 'Take My Wife.'

The couple's new show puts a fresh spin on a classic format.

Stop me if you've heard this one before:

Imagine a sitcom based on the life of a stand-up comedian. Maybe there's some stage work thrown in for show, but for the most part, the story follows the life of the comic in his or her everyday life, friendships, romantic relationships, and the like. If that sounds familiar, it's because it's been done many, many times over. Think "Seinfeld" or "Louie," for example.

"Take My Wife," a new sitcom from NBCUniversal's Seeso digital streaming service, manages to take that well-worn premise and transform it into something entirely new and engaging. The story centers on the lives of real-life comics (and real-life couple) Cameron Esposito and Rhea Butcher, a duo in their early-30s living in L.A. who co-host a stand-up show at a local comedy club.


All GIFs from Seeso.

Originally sold as a stand-up show, Esposito and Butcher later re-pitched it as single-camera scripted show built around sketches of their lives off the stage.

"Beyond how awesome stand-up is, we really wanted to talk about, you know, our lives as small business people who happen to do stand-up for a living," Esposito says.

"It's just a sitcom relationship about two people trying to figure out how to make it work." — Cameron Esposito

And it's a good thing they did, because honestly, it's the off-stage material that makes "Take My Wife" stand out from the titles you'll find scattered throughout Netflix, Comedy Central, and HBO. Whether it's Esposito and Butcher's interactions with other comics, scenes of Butcher standing in her living room working on new material, or Esposito's meeting with an old college friend that makes her take stock of her own position in life, there's a lot packed into the roughly 20-minute episodes.

Same-sex couples remain in short supply when it comes to sitcoms. "Take My Wife" wants to change that in a big way.

"I think what I find to be so special about the show and what I hope people like about it is that our relationship and our lives are as normative as anybody's life," says Esposito. "I think we haven't yet seen that on TV. We haven't yet seen a queer couple that is dealt with as if they're any sitcom couple."

"Like, the camera doesn't slow down and candles don't get lit every time that we kiss, or there aren't dudes in our orbit that we may or may not be sleeping with on the side. It's just a sitcom relationship about two people trying to figure out how to make it work."

One of the most impressive aspects of the show is the commitment to pushing back on sometimes harmful tropes used to advance storylines for women, LGBTQ characters, and others.

One of the most hard-hitting examples happens at the beginning of the second episode, in which Butcher and Esposito discuss the merits of sex in a hypothetical TV show starring the two of them.

“I think it’s very important to show two women, I don’t know, being casually intimate with each other, but also, it’s us and we’re real people. We’re a couple," says Butcher in the episode.

"Well, if we don’t do it, then it’s like no actual lesbians on TV having sex with other women," replies Esposito. "And there’s also like no women on TV having sex with other women, period. I mean, maybe that happens, but then like, one of them dies or they both die. They’re warlords and they die or they sleep with a man and then they die or they’re like at school and they die or they’re an art professor and they die. My point is, I just want us to live."

In case you're not picking up what she's putting down, she's not wrong: Queer women tend to not fare too well in modern media. Check out Autostraddle's list of 162 (and counting) fictional lesbian and bisexual women who have been killed off on TV. (For her part, Esposito promises that no queer women will die on "Take My Wife".)

It's a funny show with a lot of substance — just don't expect it to be delivered in some sort of "after-school special" format.

"I think in terms of hot button issues that are often dealt with in [sitcoms] with these sweeping think pieces," says Esposito. "Things like sexual assault and rape jokes and queer people and bathrooms and everything that usually ends up in these very black and white situations where people are firmly against or firmly for it. I think that does a real disservice to talking about how complicated it is just to be a human being today, and there's a gray area to every single issue, and I really think that's the experience of being an outsider in some ways."

"As women, we're outsiders in our profession. As queer people, we're outsiders in the world in general. I think that the positive side of that is that you realize how much nuance there is."

Watch the trailer for "Take My Wife" below:

All episodes of "Take My Wife" are now streaming over at Seeso.com. Rhea Butcher's latest stand-up album "Butcher" will be released on August 19 from Kill Rock Stars.

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Three women, three MS journeys: How multiple sclerosis looks different for everyone

Gina, Nathalie and Helga share their reactions to being diagnosed with MS and how they stay informed and positive in the face of ever-changing symptoms.

Courtesy of Sanofi

Helga, Nathalie and Gina all have MS, and their experiences show how differently the disease can manifest.

True

It’s been 155 years since neurologist Jean-Martin Charcot gave the first lecture on a mysterious progressive illness he called “multiple sclerosis.” Since then, we’ve learned a lot. We know MS causes the immune system to attack healthy tissue, including damaging the brain and spinal cord. Resulting symptoms can be debilitating and include fatigue, blurred vision, memory problems and weakness. Huge advancements in our understanding of MS and its underlying causes, as well as treatment advances, have been made in the past few decades, but MS remains a complex and unpredictable reality for the 2.8 million+ people diagnosed around the world.

Ironically, the only real constant for people living with MS is change. There’s no set pattern or standard progression of the disease, so each person’s experience is unique. Some people with MS have mild symptoms that worsen slowly but sometimes improve, while others can have severe symptoms that drastically alter their daily lives.

All people with MS share some things in common, however, such as the need to stay informed on the ever-evolving research, find various lines of support and try to remain hopeful as they continue living with the disease.

To better understand what navigating life with MS really looks like, three women shared their MS stories with us. Their journeys demonstrate how MS can look different for different people and interestingly, how the language used to talk about the disease can greatly impact how people understand their realities.

woman with horse, woman riding horseGina loves riding her horse, Benita.Courtesy of Sanofi

Gina—Hamburg, Germany (diagnosed with relapsing multiple sclerosis in 2017)

When her youngest son was 4 months old, Gina started having problems with her eye. She’d soon learn she was experiencing optic neuritis—her first symptom of MS.

“Immediately after the diagnosis, I looked up facts on MS because I didn’t know anything about it,” Gina says. “And as soon as I knew what could really happen with this disease, I actually got scared.”

As her family’s primary income provider, she worried about how MS would impact her ability to work as a writer and editor. Her family was afraid she was going to end up in a wheelchair. However, for now, Gina’s MS is managed well enough that she still works full-time and is able to be active.

“When I tell somebody that I have MS, they often don't believe me the first time because I don't fulfill any stereotypes,” she says.

Overwhelmed by negative perspectives on living with MS, Gina sought support in the online MS community, which she found to be much more positive.

“I think it’s important to use as many positive words as you can when talking about MS.” It’s important to be realistic while also conveying hope, she says. “MS is an insidious disease that can cause many bad symptoms…that can be frightening, and you can't gloss over it, either.”

To give back to the online community that helped her so much, Gina started a blog to share her story and help others trying to learn about their diagnosis.

Though she deals with fatigue and cognitive dysfunction sometimes, Gina stays active swimming, biking, riding horses and playing with her sons, who are now 11 and 6.

Cognitive dysfunction is common in MS, with over half of people affected. It can impact memory, attention, planning, and word-finding. As with many aspects of MS, some people experience mild changes, while others face more challenges.

Gina says that while there’s still a lot of education about MS needed, she feels positive about the future of MS because there’s so much research being done.

woman in wheelchair holding medal, woman rowingNathalie is an award-winning rower with multiple international titles.Courtesy of Sanofi

Nathalie — Pennes Mirabeau, France (diagnosed with relapsing-remitting multiple sclerosis in 2002)

Nathalie was a teenager and a competitive athlete when she noticed her first symptoms of MS, but it would take four years of “limbo” before she was diagnosed.

“Ultimately, the diagnosis was more of a relief, than a shock,” she says. “Because when you have signs and you don’t know why, it’s worse than knowing, in the end, what you have.”

However, learning more about the disease—and the realities of disease progression—scared her.

“That glimpse of the future was direct and traumatic,” she says. Her neurologist explained that the disease evolves differently for everyone, and her situation might end up being serious or very mild. So, she decided to stop comparing herself to others with MS.

She said to herself, “We’ll see what happens, and you’ll manage it bit by bit.”

By 2005, Nathalie’s MS had progressed to the point of needing a wheelchair. However, that has not dampened her competitive spirit.

Nathalie began her international rowing career in 2009 and has won multiple world titles, including two Paralympic medals—silver in London and bronze in Tokyo. Now, at 42, she still trains 11 times a week. Fatigue can be a problem, and sometimes hard workouts leave her with muscle stiffness and shaking, but she credits her ongoing sports career for helping her feel in tune with her body’s signals.

“Over the years, I’ve learned to listen to my body, letting my body guide when I need to stop and take breaks,” she says.

Nathalie explains that she used to only look backwards because of the initial shock of her diagnosis. In time, she stopped thinking about what she couldn’t do anymore and focused on her future. She now lives in the following mindset: “Even when doors close, don’t miss out on those that open.” Instead of focusing on what she can’t do, she focuses on the opportunities she still has. Right now, this includes her training for the 2024 Paralympic Games in Paris, where she will compete for another rowing medal.

“I only go forward,” she says. “Well, I try, anyway…It’s easy to say, it’s not always easy to do. But that’s what I try to do.”

woman exiting water after swimming, woman with great daneHelga's Great Dane has become a helpful and beloved companion.Courtesy of Sanofi

Helga—Johannesburg, South Africa (diagnosed with relapsing multiple sclerosis in 2010)

When Helga first started having balance issues and numbness in her feet, she chalked it up to her training as a runner. But when the numbness moved to her face, she knew something was wrong. She never guessed it was MS.

“When I was diagnosed, I felt completely overwhelmed and clueless,” Helga says. “I felt that I had nowhere near enough information. I did not know anything about the disease…I had no idea that it was going to be a process of continually monitoring and adjusting your lifestyle.”

In the beginning, Helga’s symptoms developed slowly, and she didn’t appear ill to others. She was even able to run for a few years after her diagnosis, but she couldn’t do marathons anymore, and she began to fall frequently due to balance issues and right-foot dragging. Then her cognition issues became more problematic, especially in her job as a trainer in a printing company.

“My executive function, decision-making and short-term memory were affected to the point that I was eventually medically unfit for work,” she says. She stopped working in 2017.

However, she didn’t stop living life. Even though she could no longer run, she continued to swim competitively. She got a Great Dane puppy and trained him as a service dog to help her walk. She also serves as vice chair of the patient support organization Multiple Sclerosis South Africa, and she advises others who have been diagnosed to join a patient advocacy group as soon as possible to get reliable information and meet others with MS.

Helga says she is “hopeful” about the future of MS. “I must say that I am so grateful that we have all the new medications available, because my life would not be the same if it wasn't for that,” she adds.

Part of how she manages her MS is by looking at the positives.

“If I could tell the world one thing about MS, it would be that MS is an incurable disease of the nervous system, but it's also the greatest teacher of valuing your health, family, friends, and managing change in your life,” she says. “My life is diversified in a way that I never, ever thought it would, and MS has been honestly the greatest teacher.”

Each MS journey is unique – with each person impacted experiencing different struggles, successes, and feelings as they manage this unpredictable disease. But the common thread is clear – there is a critical need for information, support, and hope. We are proud to participate in World MS Day and share these incredible stories of living life while living with MS. To learn more about MS, go to https://www.sanofi.com/why-words-really-matter-when-it-comes-to-multiple-sclerosis.

MAT-GLB-2301642-v1.0-05/2023

This article was sponsored by Sanofi. Participants were compensated when applicable.

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