Annie Reneau

Those whose lives have been affected by Alzheimer's know the pain of slowly losing a loved one long before they're actually gone. Dementia is a cruel diagnosis, and it's hard to overstate how difficult it is to endure someone you know well forgetting who you are.

So when a family gets a glimpse of clarity, a moment of lucidity when their loved one remembers and is present with them, it's a gift beyond compare. That's why a viral video of a woman and her granddaughter on graduation day, when her Alzheimer's seemingly "disappeared" for five minutes, has left everyone a teary mess.

TikTok user @paige.lake shared that it was a moment she'd never forget, as her grandmother saw her in graduation regalia and knew exactly who she was. With Paige in tears, her grandmother tells her she likes her jewelry and says she looks "fantastic." As she hugs Paige, she says, "Don't get so upset!"

People requested the video without the music so they could hear her more clearly, and Paige obliged.

Some people said they should have stuck with the version with music, because phew.

"Crying even HARDER now hearing her words clearly 😭 bless you both. 🤍"

"I cried when I couldn't hear what she said and now I can't stop crying.. my mom had dementia and I know those moments she remember was the most precious moments so I understand how you feel. God bless 🥺"

"I literally have no tears left in my body right now, my grandma has suffered from Alzheimer for almost 10 years now, so this video got me extremely emotional. I am so so happy for you. 🥹"

"Me balling my eyes out because I also got those five minutes with my nana who passed of the same 🥹 God bless you guys. ❤️"

"Stop it 🥺🥺🥺🥺 she's never ever forgotten how much she loves you ❤"

The love of a grandparent is a gift.Photo credit: Canva

People with experience caring for dementia patients shared their own stories, as well as insights into what was happening in Paige's video, making the moment all the more meaningful.

"Dementia worker here! That's 'cause this isn't just her short term memory. She's been dreaming about your future for a long time love. This is a moment she's been waiting to see. She'd never forget that.💗"

"You know that's moment she always wanted to be there for. Her brain gave her a reprieve."

"It's because she has dreamt about this moment for SO LONG. Alzheimers affects short term memory. Shes seen you in that gown since you were a little girl. You fulfilled 2 people's dreams that day 🥺"

"Mine did that on my wedding day. She walked over and said, 'When did you grow up and become a beautiful bride, Kandi?'"

"I just remembered when my grandpa also broke through Alzheimer's for 5 mins and said I looked beautiful on my hs graduation. 😭"

Scientists are trying to find a cure for Alzheimer's disease.Photo credit: Canva

What's the latest in Alzheimer's research?

According to the Alzheimer's Association, there are approximately 7.2 million Americans with Alzheimer's disease, which means many more millions of people are affected by it. The University of California reports that Alzheimer's affects 10 percent of people over age 65 and kills more people annually than breast and prostate cancer combined.

However, after decades of research into treatment and prevention, researchers are beginning to see promising results that offer hope for the future.

"We've had thousands of failed clinical trials and made very little progress against this devastating disease for decades," said Martin Kampmann, professor of biochemistry and biophysics who studies the molecular aspects of dementia at UC San Francisco. "But just over the last five or so years, we've hit an inflection point. We're starting to get traction."

There are two FDA-approved drugs that target the underlying causes of Alzheimer's disease and can delay cognitive impairment by up to seven months. But those drugs don't reverse or cure the disease, and significant side effects may give some families pause.

However, the discovery of a compound that increases gamma oscillations, brain signals that regulate connectivity between different brain regions and affect cognitive processes like working memory, offers the potential not just for treatment but for the reversal of cognitive decline. In a 2024 study led by Istvan Mody, a professor of neurology and physiology at UCLA Health, the compound was given to mice with Alzheimer's disease. Prior to treatment, the mice couldn't remember how to navigate a maze. Afterward, they were nearly as good at getting through it as mice without Alzheimer's.

"We've shown that this works in mice," said Mody. "If we can develop a therapy that's safe and effective for people, we may be able to restore cognitive function. That's the ultimate hope."

Additionally, a 2025 study from Case Western University tested a pharmaceutical intervention in mice with advanced Alzheimer's. The research showed that the brain’s failure to maintain normal levels of NAD+, a central cellular energy molecule, is a major driver of Alzheimer's disease. The study used a pharmacological agent to maintain proper NAD+ balance, resulting in a recovery of cognitive function in the mice. It's another glimpse of hope, especially if those results carry over to human clinical trials.

Many scientists are working on dementia-related diseases and making progress. In the meantime, families like Paige's will take whatever moments they can get with loved ones who have Alzheimer's.