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Innovation

Science

Health experts created a patch that can repair damaged hearts

German scientists found a way to fix a broken heart—literally

A new patch made of human cells could help repair damage from heart failure.

Scientists at the University Medical Center Göttingen in Germany have found a way to mend hearts. Not the metaphorical version, but literal flesh-and-blood hearts! Through cell manipulation they have successfully tested a patch that can strengthen heart tissue for those with heart disease and advanced heart failure.

“We now have, for the first time, a laboratory grown biological transplant available, which has the potential to stabilize and strengthen the heart muscle,” said co-author of the study, Prof. Ingo Kutschka to The Guardian.

In this study, the researchers took blood cells from a donor and “reprogrammed” them into mimicking stem cells. This allowed those cells to further change into heart muscle cells and connective tissue cells. After combining these cells with collagen, the scientists were able to create a graftable patch that could be implanted onto a damaged area of the heart to increase its strength. In fact, the completed heart muscle patches have the characteristics of a heart that is only four to eight years old.

Doctor checking a person's heart with a stethoscopeThese patches could help many people with heart problems.Photo credit: Canva

The reason for this experiment was two-fold. First, it was done to explore other health care options for people who need a donated heart, which is typically a very long waitlist. Secondly, because previous methods of injecting heart muscle cells into the heart have led to patients experiencing tumors or an irregular heartbeat, both of which could be fatal.

Initial trials of this heart patch have been promising. After successful trials with macaque monkeys, the researchers approached a 46-year-old woman with advanced heart failure to treat her with patches made with human cells after a minimally invasive procedure. Three months afterward, the patient received a transplant and the scientists were able to study her discarded heart that they had patched to see how effective their treatment was. They found that not only did the patches survive but they had developed their own blood supply.

While this is definitely great news for heart patients, there still needs to be further testing. As of now, it takes three to six months for these patches to fully benefit the patient, meaning that transplants would be prioritized for patients that urgently need a new heart. However, fifteen patients have been approved for the procedure and are currently being monitored with their new heart patches.

Surgeons with a box that says "Human Organ for Transplant"While this heart patch is an option, it cannot fully replace human heart transplants.Photo credit: Canva

While advances in heart medicine are great news overall, further research is needed to make sure this and other advances are viable in the long term. In the meantime, it’s best for everyone to take steps to ensure maximum heart health. This may sound like an afterschool special or a basic lesson in health class, but according to American Heart Association nearly half of American adults have a cardiovascular issue, so it might be good to have a refresher.

Woman checking her heart rate outside.Running and other cardiovascular exercise helps keep your heart rate up and helps keep your heart healthy.Photo credit: Canva

Make sure your diet is rich with heart-healthy foods like vegetables and fish, with little to no added fat, sugar, or salt. Exercise at least 150 minutes per week to keep your heart rate strong. Visit your doctor with regular check-ups to keep track of your overall health, so you can both create a treatment plan if something comes up.

Over time, more and more medical breakthroughs will occur, but it’ll be better to do what you can to ensure you’ll be around to see them.

Carl Sagan and a sliced apple

The concept of the fourth dimension seems beyond human comprehension. As three-dimensional beings, we are unable to see beyond a physical object's height, width and depth. What else could there be?

Enter Carl Sagan, revered as one of the greatest science communicators of his time. He possessed a unique gift for demystifying complex scientific concepts, making them accessible and thrilling for the general public. In 1980, on Episode 10 of the groundbreaking PBS show “Cosmos,” Sagan embarked on a mission to explain the seemingly impossible fourth dimension.

What’s excellent about Sagan’s explanation is that he uses simple and relatable objects: an apple and a Tesseract, or a hypercube.

Sagan began by discussing how a two-dimensional being living in a flat world would perceive a three-dimensional object like an apple.

“Imagine we live in this ‘flatland’/2-D plane with no concept of ‘up’ or ‘down.’ Then along comes a 3-D object like an apple. We do not even notice it until it crosses our plane of existence — and even then, we have no idea what the apple is,” Sagan explains. “We see only a fragment as it passes through our plane. There is no way we can comprehend the 3-D quality/dimension of the apple, because it is more than we can understand. We only have the evidence of what has passed through our plane.”

Sagan then related this two-dimensional experience of the third dimension to how we might try to understand the fourth. To do so, he used the Tesseract, a four-dimensional cube, to demonstrate how difficult it is for us to perceive or visualize dimensions beyond our own three. At this point, Sagan is asking the viewer to expand their minds to understand the fourth dimension metaphorically.

Sagan’s demonstration of the fourth dimension isn’t just a wonderful explanation of a scientific idea that many of us find difficult to comprehend; it’s also a great example of how to teach complex ideas by combining clear explanations with thought-provoking visuals.


This article originally appeared last year.

via @Sidneyraz / TikTok

TikTok has become a great place for finding life hacks and one of the best follows is @Sidneyraz. His hook is that he shows people the "things I wish I knew before I was in my 30s." Most of his life hacks are simple, domestic tricks for cleaning the house or preparing food. But he also shares some financial advice and makes the personal admission that "not being hungover is better than being drunk."

That's a lesson that a lot of us wish we learned sooner. Like a lot of folks, Sidney is learning a lot of domestic skills in his third decade and that makes sense. That's the time when people begin to settle down with a significant other and pick up more domestic skills.

The good news is that he's not going through this life change alone. He wants to share all of it with you.

Here are 11 of his best life hacks.

Baking bacon is better than frying:

@sidneyraz

baking bacon is better than frying bacon #inmy30s #bacon


How to eat a flat chicken wing:

@sidneyraz

learned this on hot ones #inmy30s #chickenwings


A tooth-brushing trick:

@sidneyraz

30+ years of being wrong #inmy30s #oralhealth


How to stop a pot from boiling over:

@sidneyraz

it has helped many times #inmy30s #cookingtips


You can vacuum more than just your floor:

@sidneyraz

vacuuming more than just floors #inmy30s #vaccum


Did you know your dishwasher has a filter?

@sidneyraz

cleaning the dishes robot is a thing #inmy30s #dishwasher


The weatherman isn't saying what you think he's saying:

@sidneyraz

but what is the forecasted area?? #weatherreport #inmy30s


How to fill a cooler:

@sidneyraz

have a great summer y’all #inmy30s #summervibes2021


The secret behind Chinese food containers:

@sidneyraz

first time trying this #chinesefood #takeout #tipsandtricks


Hire movers:

@sidneyraz

your body will thank you #inmy30s #movingday


Not being hungover is better than being drunk:

@sidneyraz

goodbye youth. #inmy30s


This article originally appeared four years ago.

Innovation

A student accidentally created a rechargeable battery that could last 400 years

"This thing has been cycling 10,000 cycles and it’s still going." ⚡️⚡️

There's an old saying that luck happens when preparation meets opportunity.

There's no better example of that than a 2016 discovery at the University of California, Irvine, by doctoral student Mya Le Thai. After playing around in the lab, she made a discovery that could lead to a rechargeable battery that could last up to 400 years. That means longer-lasting laptops and smartphones and fewer lithium ion batteries piling up in landfills.

A team of researchers at UCI had been experimenting with nanowires for potential use in batteries, but found that over time the thin, fragile wires would break down and crack after too many charging cycles. A charge cycle is when a battery goes from completely full to completely empty and back to full again.

But one day, on a whim, Thai coated a set of gold nanowires in manganese dioxide and a Plexiglas-like electrolyte gel.

"She started to cycle these gel capacitors, and that's when we got the surprise," said Reginald Penner, chair of the university's chemistry department. "She said, 'this thing has been cycling 10,000 cycles and it's still going.' She came back a few days later and said 'it's been cycling for 30,000 cycles.' That kept going on for a month."

This discovery is mind-blowing because the average laptop battery lasts 300 to 500 charge cycles. The nanobattery developed at UCI made it though 200,000 cycles in three months. That would extend the life of the average laptop battery by about 400 years. The rest of the device would have probably gone kaput decades before the battery, but the implications for a battery that that lasts hundreds of years are pretty startling.

Batteries being recycled at WRWA, London. Nov ‘21Photo by John Cameron on Unsplash

"The big picture is that there may be a very simple way to stabilize nanowires of the type that we studied," Penner said. "If this turns out to be generally true, it would be a great advance for the community." Not bad for just fooling around in the laboratory.


This article originally appeared two years ago.