+
upworthy
Health

New first-of-its-kind treatment for alopecia that triggers hair growth approved by FDA

The current treatment for alopecia is painful and long—this could change lives.

alopecia; hair loss

New treatment for alopecia.

Alopecia is something that affects people of all ethnicities, all over the world, and unfortunately effective treatment has been scarce. But there's potentially good news on the horizon for hair loss suffers. The FDA recently approved a drug called Olumiant, a systemic treatment for alopecia areata, the autoimmune disorder that causes hair loss. The drug works by interfering with the body’s confused messaging that tells it to attack hair follicles.


The world became instantly familiar with the word alopecia after the 2022 Oscars, where Will Smith infamously defended his wife, Jada Pinkett Smith, after Chris Rock made a joke about her baldness. Pinkett Smith has alopecia and decided to forego treatment and instead to simply shave her head. She talked about how painful the treatments are on a recent episode of Red Table Talk. On the episode, a dermatologist explained the localized treatment, which involves needle pricks directly into the scalp with a needle containing medication. The process is lengthy and painful, and requires frequent visits for these scalp jabs in an attempt to stave off further hair loss. It’s no wonder that many people decide to embrace balding and shave their head instead.

The newly approved drug has been on the market in the U.S. since 2018 as a treatment for rheumatoid arthritis, and while it does have several mild to moderate side effects, one of them, hair regrowth, is what drew attention to it as a treatment for alopecia areata. The best news is that it's taken orally, and doesn’t involve any tiny jabs in the scalp.

In the FDA's announcement, Dr. Kendall Marcus, director of the Division of Dermatology and Dentistry in the FDA’s Center for Drug Evaluation and Research, said, “Access to safe and effective treatment options is crucial for the significant number of Americans affected by severe alopecia. Today's approval will help fulfill a significant unmet need for patients with severe alopecia areata."

In the clinical trials, between 32% and 35% of patients who received the higher of two tested doses had enough hair to cover 80% of their scalp after 36 weeks (compared with between 3% and 5% of patients who received a placebo). This definitely shows promise, despite observed side effects such as respiratory infections, acne, high cholesterol, headaches, fatigue, urinary tract infections and more. If you’ve ever watched a commercial for a new medication, these side effects shouldn’t come as a surprise, nor should they derail the excitement of a medication that could boost so many people’s mental health.

To date, there hasn't really been an effective noninvasive treatment for alopecia areata and while the condition isn’t life threatening, the mental effects can be detrimental. On the episode of Red Table Talk, the mother of 12-year-old Rio Allred told of how her daughter died by suicide, which she believed was linked to the bullying she received due to her alopecia. Depression, anxiety and negative body image are all risks associated with having the hair loss condition, especially in women.

While this new treatment won't be effective on everyone and it comes with a daunting number of potential side effects, it certainly offers hope for many as an improvement over the standard "needle" treatment. Hopefully researchers will continue to make progress on treatments for alopecia that are readily available and safe.

Planet

Easy (and free!) ways to save the ocean

The ocean is the heart of our planet. It needs our help to be healthy.

Ocean Wise

Volunteers at a local shoreline cleanup

True

The ocean covers over 71% of the Earth’s surface and serves as our planet’s heart. Ocean currents circulate vital heat, moisture, and nutrients around the globe to influence and regulate our climate, similar to the human circulatory system. Cool, right?

Our ocean systems provide us with everything from fresh oxygen to fresh food. We need it to survive and thrive—and when the ocean struggles to function healthfully, the whole world is affected.

Pollution, overfishing, and climate change are the three biggest challenges preventing the ocean from doing its job, and it needs our help now more than ever. Humans created the problem; now humans are responsible for solving it.

#BeOceanWise is a global rallying cry to do what you can for the ocean, because we need the ocean and the ocean needs us. If you’re wondering how—or if—you can make a difference, the answer is a resounding YES. There are a myriad of ways you can help, even if you don’t live near a body of water. For example, you can focus on reducing the amount of plastic you purchase for yourself or your family.

Another easy way to help clean up our oceans is to be aware of what’s known as the “dirty dozen.” Every year, scientists release an updated list of the most-found litter scattered along shorelines. The biggest culprit? Single-use beverage and food items such as foam cups, straws, bottle caps, and cigarette butts. If you can’t cut single-use plastic out of your life completely, we understand. Just make sure to correctly recycle plastic when you are finished using it. A staggering 3 million tons of plastic ends up in our oceans annually. Imagine the difference we could make if everyone recycled!

The 2022 "Dirty Dozen" ListOcean Wise

If you live near a shoreline, help clean it up! Organize or join an effort to take action and make a positive impact in your community alongside your friends, family, or colleagues. You can also tag @oceanwise on social if you spot a beach that needs some love. The location will be added to Ocean Wise’s system so you can submit data on the litter found during future Shoreline Cleanups. This data helps Ocean Wise work with businesses and governments to stop plastic pollution at its source. In Canada, Ocean Wise data helped inform a federal ban on unnecessary single-use plastics. Small but important actions like these greatly help reduce the litter that ends up in our ocean.

Ocean Wise, a conservation organization on a mission to restore and protect our oceans, is focused on empowering and educating everyone from individuals to governments on how to protect our waters. They are making conservation happen through five big initiatives: monitoring and protecting whales, fighting climate change and restoring biodiversity, innovating for a plastic-free ocean, protecting and restoring fish stocks, and finally, educating and empowering youth. The non-profit believes that in order to rebuild a resilient and vibrant ocean within the next ten years, everyone needs to take action.

Become an Ocean Wise ally and share your knowledge with others. The more people who know how badly the ocean needs our help, the better! Now is a great time to commit to being a part of something bigger and get our oceans healthy again.

It's incredible what a double-sided magnet can do.


A new trend in treasure hunting called magnet fishing has blown up over the past two years, evidenced by an explosion of YouTube channels covering the hobby. Magnet fishing is a pretty simple activity. Hobbyists attach high-powered magnets to strong ropes, drop them into waterways and see what they attract.

The hobby has caught the attention of law enforcement and government agencies because urban waterways are a popular place for criminals to drop weapons and stolen items after committing a crime. In 2019, a magnet fisherman in Michigan pulled up an antique World War I mortar grenade and the bomb squad had to be called out to investigate.


Keep ReadingShow less

Author Mark Tyler Nobleman and Batman and Robin.

Over the past few years, "Don't Say Gay" bills have been introduced across the U.S., sparking widespread controversy about how LGBTQ issues should be addressed in schools. Supporters argue they protect children from inappropriate content by restricting discussions of sexual orientation and gender identity in educational settings.

Opponents believe these bills marginalize LGBTQ individuals by fostering stigma and potentially infringing on teachers' ability to openly address students' questions or experiences.

Currently, 11 states have banned LGBTQ discussion in public schools, and 5 require parental consent.

Author and comic book expert Marc Tyler Nobleman recently found himself at the center of the controversy, and his simple rationale for using the word “gay” in his school presentations presents an age-appropriate and inclusive way to approach at the issue.

Keep ReadingShow less
Science

Researchers dumped tons of coffee waste into a forest. This is what it looks like now.

30 dump truck loads and two years later, the forest looks totally different.

One of the biggest problems with coffee production is that it generates an incredible amount of waste. Once coffee beans are separated from cherries, about 45% of the entire biomass is discarded.

So for every pound of roasted coffee we enjoy, an equivalent amount of coffee pulp is discarded into massive landfills across the globe. That means that approximately 10 million tons of coffee pulp is discarded into the environment every year.

Keep ReadingShow less

The Preussen Munster square off against the Würzburger Kickers

As a soccer match between German teams Preussen Munster and Würzburger Kickers went into its final minutes, a defender from the Kickers, 23-year-old Leroy Kwadwo, stopped to point out a problem in the stands.

A Munster fan was making monkey noises at Kwadwo, a black player of Ghanaian descent. It was a clearly racist heckling—an issue that has publicly plagued the international sport in various venues, even as recently as last week. But this time, the response from the crowd far outshined the racist in the stands.

Keep ReadingShow less
Health

Women are shocking their boyfriends by showing them how tampons actually work

The viral videos are a great way to educate men on a sensitive topic.

via TikTok

Menstrual taboos are as old as time and found across cultures. They've been used to separate women from men physically — menstrual huts are still a thing — and socially, by creating the perception that a natural bodily function is a sign of weakness.

Even in today's world women are deemed unfit for positions of power because some men actually believe they won't be able to handle stressful situations while mensurating.

"Menstruation is an opening for attack: a mark of shame, a sign of weakness, an argument to keep women out of positions of power,' Colin Schultz writes in Popular Science.

Keep ReadingShow less
Upworthy/Instagram

The Shinsekis certainly had a sense of humor.

As anyone who has dipped their toe into home improvement waters knows, home remodeling is a mix of excitement and headaches. It's fun to freshen things up and make your own mark on your home, but when you're tearing out the old, you never know what you're going to find. Something toxic like asbestos or mold? Something cool like money or a box of treasures?

How about a photo of previous homeowners introducing themselves and ribbing you for undoing all their hard work?

That's what one home remodeler found when they started remodeling their bathroom, and the notes the former owners left for them are leaving people in stitches.

Keep ReadingShow less