Mountain gorillas were just taken off the 'critically endangered' species list.
Photo by Ivan Lieman/AFP/Getty Images.

On Thursday, the Conservation of Nature announced a major win in fight to save mountain gorillas.

The gorilla population has been designed from "critically endangered" to "endangered" as their population has nearly doubled over the past decade. The latest numbers say there are over 1,000 mountain gorillas in the wild, up from just over 600.

After teetering on the brink of extinction, mountain gorilla numbers are on the rise. That's awesome news.

Living in East Africa's Virunga Mountains and highlighted in the movie "Gorillas in the Mist" (in which Sigourney Weaver played primatologist and conservationist Dian Fossey), critically endangered mountain gorillas have been battling extinction for decades.


Image via Brent Stirton/Getty Images.

In 1981, when their numbers had plunged to 242, Fossey doubted that the species would survive into the 21st century. Thanks in large part to concerted effort from conservationists, however, their population has slowly but steadily grown. In 2010, there were 480 animals, and as of a June 2016 census there were 604. With an estimate of several hundred uncounted gorillas roaming the forests, that number could be close to 1000.

But they are not totally out of the woods yet.  

Habitat loss and poaching are the biggest threats to gorillas.

Human encroachment and deforestation due to agriculture, livestock grazing, and firewood collection threaten the mountain gorillas' habitat. In addition, people are burning trees inside the forest to create charcoal — a commodity that makes up a massive illegal trade industry in an area with limited economic options.

Poachers going after other animals, such as antelope or bush pigs, also catch gorillas in their wire snares. When a gorilla can't remove a snare, it can end up losing a limb or dying from gangren.

Such threats are a byproduct of an overarching reality: human economic strife.

Battling economic inequality is a key to saving endangered species.

In order to mitigate threats to endangered species, we need to understand why those threats exist in the first place. Most people aren't on a mission to kill animals or destroy the environment; they're on a mission to live. When economic options are limited, people do what they have to, which often means sacrificing long-term sustainability for short-term survival.  

In other words, we can save endangered species by eliminating the economic need that drives the industry that threatens conservation.

Patrick Karabaranga, a warden at Virunga National Park, plays with an orphaned mountain gorilla in the gorilla sanctuary east of the Democratic Republic of Congo. Image via AFP/Stringer/Getty Images.

Researchers at Canada's McGill University highlighted the correlation between poverty and species protection in a 2007 study of 45 countries and 45 U.S. states. They found that income inequality actually predicts the number of threatened species in an area. The greater the unequal distribution of income, the greater the loss of biodiversity.

This correlation has clearly played out in the story of mountain gorillas. Rwanda and the Democratic Republic of the Congo — the two countries bordering the Virunga Mountains — have some of the highest economic inequality in the world. However, Rwanda in particular has made significant strides to reduce inequality — and as it has made those strides, gorilla populations in the region have increased.

For this very reason, Dian Fossey's organization uses the tagline: "Helping People. Saving Gorillas."

Folks at the Dian Fossey International Gorilla Fund understand that economy and ecology are intertwined. That's why a significant part of their work is helping develop the communities in the regions near gorilla habitats.

"When people have to focus on basic survival, this puts additional pressure on the environment, such as using the forests for hunting, firewood, water, or crop land," the organization's website says. "The Fossey Fund has programs targeted at meeting basic needs in these communities, which not only helps people, but also supports effective conservation efforts."

Economic inequality is a complex issue, and certainly not the only driving factor threatening endangered species — but it's a big one. "With biodiversity loss, if we don’t link the science to the social causes, we will never solve the problem" said Dr. Andrew Gonzalez, associate professor and Canada Research Chair in biodiversity.

Mountain gorilla research has offered a real-world example of this truth. As the Fossey Fund states, "Only when people are thriving can gorillas, other wildlife, and their habitats thrive, too."

via Pixabay

Talking about politics at work can be a really touchy situation. It's good for people to be able to express themselves in the office. But it can lead to serious tension when people don't see eye-to-eye. It can be especially difficult when a company takes a hard line on a controversial issue that employees are forced to stand behind.

So Basecamp, a project management software company based in Chicago, has just decided to ban talking about politics at work altogether. It seems the company tried to foster an open atmosphere but it backfired.

"Sensitivities are at 11, and every discussion remotely related to politics, advocacy, or society at large quickly spins away from pleasant," co-founder Jason Fried wrote in a post on the company website.

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via Pixabay

Talking about politics at work can be a really touchy situation. It's good for people to be able to express themselves in the office. But it can lead to serious tension when people don't see eye-to-eye. It can be especially difficult when a company takes a hard line on a controversial issue that employees are forced to stand behind.

So Basecamp, a project management software company based in Chicago, has just decided to ban talking about politics at work altogether. It seems the company tried to foster an open atmosphere but it backfired.

"Sensitivities are at 11, and every discussion remotely related to politics, advocacy, or society at large quickly spins away from pleasant," co-founder Jason Fried wrote in a post on the company website.

Keep Reading Show less
True

Each year, an estimated 1.8 million people in the United States are affected by cancer — most commonly cancers of the breast, lung, prostate, and blood cancers such as leukemia. While not everyone overcomes the disease, thanks to science, more people are surviving — and for longer — than ever before in history.

We asked three people whose lives have been impacted by cancer to share their stories – how their lives were changed by the disease, and how they're using that experience to change the future of cancer treatments with the hope that ultimately, in the fight against cancer, science will win. Here's what they had to say.

Celine Ryan, 55, engineer database programmer and mother of five from Detroit, MI

Photo courtesy of Celine Ryan

In September 2013, Celine Ryan woke up from a colonoscopy to some traumatic news. Her gastroenterologist showed her a picture of the cancerous mass they found during the procedure.

Ryan and her husband, Patrick, had scheduled a colonoscopy after discovering some unusual bleeding, so the suspicion she could have cancer was already there. Neither of them, however, were quite prepared for the results to be positive -- or for the treatment to begin so soon. Just two days after learning the news, Ryan had surgery to remove the tumor, part of her bladder, and 17 cancerous lymph nodes. Chemotherapy and radiation soon followed.

Ryan's treatment was rigorous – but in December 2014, she got the devastating news that the cancer, once confined to her colon, had spread to her lungs. Her prognosis, they said, was likely terminal.

But rather than give up hope, Ryan sought support from online research, fellow cancer patients and survivors, and her medical team. When she brought up immunotherapy to her oncologist, he quickly agreed it was the best course of action. Ryan's cancer, like a majority of colon and pancreatic cancers, had been caused by a defect on the gene KRAS, which can result in a very aggressive cancer that is virtually "undruggable." According to the medical literature, the relatively smooth protein structure of the KRAS gene meant that designing inhibitors to bind to surface grooves and treat the cancer has been historically difficult. Through her support systems, Ryan discovered an experimental immunotherapy trial at the National Institutes of Health (NIH) in Bethesda, MD., and called them immediately to see if she was eligible. After months of trying to determine whether she was a suitable candidate for the experimental treatment, Ryan was finally accepted.

The treatment, known as tumor-infiltrating lymphocyte therapy, or TIL, is a testament to how far modern science has evolved. With this therapy, doctors remove a tumor and harvest special immune cells that are found naturally in the tumor. Doctors then grow the cells in a lab over the next several weeks with a protein that promotes rapid TIL growth – and once the cells number into the billions, they are infused back into the patient's body to fight the cancer. On April 1, 2015, Ryan had her tumor removed at the NIH. Two months later, she went inpatient for four weeks to have the team "wash out" her immune system with chemotherapy and infuse the cells – all 148 billion of them – back into her body.

Six weeks after the infusion, Ryan and Patrick went back for a follow-up appointment – and the news they got was stunning: Not only had no new tumors developed, but the six existing tumors in her lungs had shrunk significantly. Less than a year after her cell infusion, in April 2016, the doctors told Ryan news that would have been impossible just a decade earlier: Thanks to the cell infusion, Ryan was now considered NED – no evaluable disease. Her body was cancer-free.

Ryan is still NED today and continuing annual follow-up appointments at the NIH, experiencing things she never dreamed she'd be able to live to see, such as her children's high school and college graduations. She's also donating her blood and cells to the NIH to help them research other potential cancer treatments. "It was an honor to do so," Ryan said of her experience. "I'm just thrilled, and I hope my experience can help a lot more people."

Patrice Lee, PhD, VP of Pharmacology, Toxicology and Exploratory Development at Pfizer

Photo courtesy of Patrice Lee

Patrice Lee got into scientific research in an unconventional way – through the late ocean explorer Jacques Cousteau.

Lee never met Cousteau but her dreams of working with him one day led her to pursue a career in science. Initially, Lee completed an undergraduate degree in marine biology; eventually, her interests changed and she decided to get a dual doctoral degree in physiology and toxicology at Duke University. She now works at Pfizer's R&D site in Boulder, CO (formerly Array BioPharma), leading a group of scientists who determine the safety and efficacy of new oncology drugs.

"Scientists focused on drug discovery and development in the pharmaceutical industry are deeply committed to inventing new therapies to meet unmet needs," Lee says, describing her field of work. "We're driven to achieve new medicines and vaccines as quickly as possible without sacrificing safety."

Among the drugs Lee has helped develop during her career, including cancer therapies, she says around a dozen are currently in development, while nine have received FDA approval — an incredible accomplishment as many scientists spend their careers without seeing their drug make it to market. Lee's team is particularly interested in therapies for brain metastases — something that Lee says is a largely unmet need in cancer research, and something her team is working on from a variety of angles. "Now that we've had rapid success with mRNA vaccine technology, we hope to explore what the future holds when applying this technology to cancers," Lee says.

But while evaluating potential cancer therapies is a professional passion of Lee's, it's also a mission that's deeply personal. "I'm also a breast cancer survivor," she says. "So I've been on the other side of things and have participated in a clinical trial."

However, seeing how melanoma therapies that she helped develop have affected other real-life cancer patients, she says, has been a highlight of her career. "We had one therapy that was approved for patients with BRAF-mutant metastatic melanoma," Lee recalls. "Our team in Boulder was graced by a visit from a patient that had benefited from these drugs that we developed. It was a very special moment for the entire team."

None of these therapies would be available, Lee says without rigorous science behind it: "Facts come from good science. Facts will drive the development of new drugs, and that's what will help patients."

Chiuying "Cynthia" Kuk (they/them) MS, 34, third-year medical student at Michigan State University College of Human Medicine

Photo courtesy of Cynthia Kuk

Cynthia Kuk was just 10 years old when they had a conversation that would change their life forever.

"My mother, who worked as a translator for the government at the time, had been diagnosed with breast cancer, and after her chemotherapy treatments she would get really sick," Kuk, who uses they/them pronouns, recalls. "When I asked my dad why mom was puking so much, he said it was because of the medicine she was taking that would help her get better."

Kuk's response was immediate: "That's so stupid! Why would a medicine make you feel worse instead of better? When I'm older, I want to create medicine that won't make people sick like that."

Nine years later, Kuk traveled from their native Hong Kong to the United States to do exactly that. Kuk enrolled in a small, liberal arts college for their Bachelor's degree, and then four years later started a PhD program in cancer research. Although Kuk's mother was in remission from her cancer at the time, Kuk's goal was the same as it had been as a 10-year-old watching her suffer through chemotherapy: to design a better cancer treatment, and change the landscape of cancer research forever.

Since then, Kuk's mission has changed slightly.

"My mom's cancer relapsed in 2008, and she ended up passing away about five years after that," Kuk says. "After my mom died, I started having this sense of urgency. Cancer research is such that you work for twenty years, and at the end of it you might have a fancy medication that could help people, but I wanted to help people now." With their mother still at the forefront of their mind, Kuk decided to quit their PhD program and enter medical school.

Now, Kuk plans to pursue a career in emergency medicine – not only because they are drawn to the excitement of the emergency room, but because the ER is a place where the most marginalized people tend to seek care.

"I have a special interest in the LGBTQ+ population, as I identify as queer and nonbinary," says Kuk. "A lot of people in this community and other marginalized communities access care through the ER and also tend to avoid medical care since there is a history of mistreatment and judgement from healthcare workers. How you carry yourself as a doctor, your compassion, that can make a huge difference in someone's care."

In addition to making a difference in the lives of LGBTQ+ patients, Kuk wants to make a difference in the lives of patients with cancer as well, like their mother had.

"We've diagnosed patients in the Emergency Department with cancer before," Kuk says. "I can't make cancer good news but how you deliver bad news and the compassion you show could make a world of difference to that patient and their family."

During their training, Kuk advocates for patients by delivering compassionate and inclusive care, whether they happen to have cancer or not. In addition to emphasizing their patient's pronouns and chosen names, they ask for inclusive social and sexual histories as well as using gender neutral language. In doing this, they hope to make medicine as a whole more accessible for people who have been historically pushed aside.

"I'm just one person, and I can't force everyone to respect you, if you're marginalized," Kuk says. "But I do want to push for a culture where people appreciate others who are different from them."