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Packard Foundation

The doctor behind a revolutionary cancer test says it all started with the support of her refugee parents

The doctor behind a revolutionary cancer test says it all started with the support of her refugee parents
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As a child, Dr. Sangeeta Bhatia's parents didn't ask her what she wanted to be when she grew up. Instead, her father would ask, "Are you going to be a doctor? Are you going to be an engineer? Or are you going to be an entrepreneur?"

Little did he know that she would successfully become all three: an award-winning biomedical and mechanical engineer who performs cutting-edge medical research and has started multiple companies.

Bhatia holds an M.D. from Harvard University, an M.S. in mechanical engineering from MIT, and a PhD in biomedical engineering from MIT. Bhatia, a Wilson professor of engineering at MIT, is currently serving as director of the Marble Center for Cancer Nanomedicine, where she's working on nanotechnology targeting enzymes in cancer cells. This would allow cancer screenings to be done with a simple urine test.

Bhatia owes much of her impressive career to her family. Her parents were refugees who met in graduate school in India; in fact, she says her mom was the first woman to earn an MBA in the country. The couple immigrated to the U.S. in the 1960s, started a family, and worked hard to give their two daughters the best opportunities.

"They made enormous sacrifices to pick a town with great public schools and really push us to excel the whole way," Bhatia says. "They really believed in us, but they expected excellence. The story I like to tell about my dad is like, if you brought home a 96 on a math test, the response would be, 'What'd you get wrong?'"


Bhatia's father saw her potential in STEM and encouraged her from an early age. "I was good at math and science, and I was a tinkerer. I was always taking apart the family answering machine," she says. "He thought that I had the potential to be an engineer and he saw that I loved my high school biology class. So he brought me actually here, to MIT, where we met a family friend, and he was using focused ultrasound to treat cancer. And that really captured my imagination, the idea that you could build instruments for a medical intervention to impact human health. That really got me excited. And so I decided to study biomedical engineering."

At first, Bhatia didn't realize what an uphill climb science and engineering fields were for women, but it soon became clear.

"Freshman year we were 50/50 women and men," she says. "And by the time I graduated senior year, there were about seven women left in the class of a hundred. And I sort of realized what everyone was talking about with how women were underrepresented in engineering...what I'd experienced was the so-called 'leaky pipeline.'

"Then when I came to graduate school, when I joined mechanical engineering, I was one of very few women," she says. "And I would say that's persisted as I go on in my career. When I joined the faculty at UC San Diego, I was one of two women. And when I start companies, I'm often the only woman pitching a room of venture capitalists. I'm sometimes the only physician in a crowd of engineers, and sometimes the only engineer in a crowd of biologists or physicians."

One thing that helped Bhatia avoid falling through the cracks herself was winning a David and Lucile Packard Foundation Fellowship for Science and Engineering — a prestigious $875,000 prize given to a select group of the nation's most promising early-career scientists and engineers.

"When you're starting out as a young professor, you have all these bright ideas about things that you want to do," she says. "But the very first thing you have to do is you have to raise resources to do those experiments, to hire the students, to staff up the lab, to buy the reagents, to do the experiments."

Raising money isn't easy. Scientific research and innovation is a long game — more of a marathon than a sprint. It can take 10 to 20 years or more for an idea to go from seed to fruition, and multiple hurdles can arise through the process. As a result, funding is often limited or tightly controlled.

But the Packard Fellowship allowed Bhatia to freely explore various ideas and innovations that might not normally receive grant funding, such as creating a functioning 3D-printed liver.

"We were interested in that idea that we could print livers, three-dimensional livers, layer by layer, with light," she says. "And so I used the fellowship to explore that, to find materials that could cross-link when they were exposed to light and that would allow us to layer liver cells and build three-dimensional livers. And that actually has turned into a whole program in my lab where we've built little livers that we hope will replace transplantation. And so that was totally seeded. It was something that was an idea. I don't think I could have ever gotten grant funding for it because I had no what we call preliminary data — it was just a thought. And it's turned into a big, successful program."

One thing that's unique about the Packard Fellowship is that the funds are unrestricted, meaning a recipient can use the money any way they see fit. That feature not only provides freedom to explore ideas, but it can be especially helpful for women in STEM. For example, Bhatia had her first daughter in 2003 — four years into her fellowship — and being able to use the funds as needed during a critical time in her career and family life was huge.

"I think one of the things that you worry a lot about when you're a young mom scientist is that balance of making an impact in your profession, but also being the mom that you always wanted to be," she says. "And the Packard Foundation allowed me to use $10,000 a year of that fund to help support quality daycare for her, or night care. So if I was going to a conference and I needed help, or if I wanted to bring her along and got a second hotel room, there were no questions asked. It was just recognized that this was a stressor, and you could use this research funding to support that dimension of your life, which was really forward thinking and unusual."

Bhatia says the expectations in science and engineering have had to change as more women have entered the field, and she's personally had to navigate how to make it all work.

"The profession grew up around people where the vision was that you would work 24/7 to advance your idea," she says. "And often you had a whole family around you that was supporting you so that you could focus on that effort. And I think when women came into the field, we had to rethink that a little bit. So I traveled less, I wanted to stay home one day a week and be with my daughter, and I had to sort of recraft a vision for the profession that I thought I wanted it to be. And one of the biggest problems is how to pay for it all. How do you cook for the family? How do you clean your house? How do you get your baby out the door? Those are very real issues. And you know, you go up for tenure and you're establishing your scientific vision when you're in your thirties. It's an incredible crunch time, so it all sort of happens at once. And those financial offsets that you can give people in those formative years—that can make a difference between whether you stay in science and whether you don't."

Bhatia dedicates time and resources toward helping girls and young women find success in the field. Realizing that many girls lose interest in math and science in middle school, Bhatia and some female friends in graduate school founded a program called Keys to Empower Youth.

"The idea was that we would bring middle school girls here from the community. Many of them had never been to a college campus and they would get to experience hands-on high-tech activities that they wouldn't have access to in the community. Also, over the course of the day, they would meet a dozen young women engineers. Those were the college students here in the Society of Women Engineers, and that's also really important for them to see in front of them. You know, girls that are just a little bit older who have chosen this profession, who are making their way, so that they can feel like it's an accessible choice for them. That program is now 25 years old and it's spread to multiple institutions."

But, Bhatia says, more needs to be done. Though women are increasingly choosing STEM careers, engineering in particular is still a highly male-dominated field.

"We're not there yet and the slope of the line is not steep enough," she says. "If we keep going at the current rate, it's going to be 2092 before we have parity in the engineering world. It's just not fast enough."

Bhatia maintains hope, however, and sees her own story as an example of what's possible.

"I'm the daughter of immigrants," she says. "I came from a part of the world where even today, not all girls are educated. And I had my parents invest in my education, and I had the benefit of amazing public schools and private institutions, and have found myself in the halls of one of the most elite places in the world. Working with the best and the brightest minds on the problems of our time. And I think that I stand in a lot of ways for what's possible in this country, to collect people from all over and to point them to what matters."

Kudos to Dr. Bhatia for being a role model for women in STEM, and to the Packard Foundation for helping fix some of the less recognized leaks in the pipeline.

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Meet the 11 outstanding nonprofits that took home this year’s Classy Awards

Each organization has gone above and beyond to make our world a better place.

All images provided by the Classy Awards, used with permission

Give these organizations all the awards

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Since 2009, the Classy Awards have celebrated nonprofits for their unique approaches to making our world a better place for everyone. Winners are given a platform to amplify their cause and showcase the positive impact of their programs.

This year, we are proud to announce that the Classy Awards have partnered with Upworthy, and we are thrilled to shine a spotlight on the 2023 winners.

From championing gender equality, to massively reducing food waste, to providing trade-based skills training to the neurodivergent community, each organization has made an incredible contribution to the betterment of our world.

Collectively through their efforts, nearly 1.5 million people and animals were served across 34 countries worldwide last year alone. That’s a win in itself.

Check out the 11 winners for 2023 below:


​412 Food Rescue

1/11

In an effort to address the growing concern of food waste, hunger, and environmental sustainability, 412 Food Rescue uses an innovative app to match volunteers, aka Food Heroes, with other organizations that might have a surplus of perfectly good but unsellable food that would otherwise be wasted and redirect it to people who need it.

Food Heroes has redirected 137 million pounds of edible food from landfills to the people who need it most.

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Mom has comical response to commenters who complained she was too old for her outfit choices

She made the cardinal offense of being 37 and daring to not dress like a grandma.

Mom responds to critics in the most comical way.

Once women reach a certain age, society does something weird. It starts sending messages that you're simply too old to dress as if you have a social life. In general, it seemed as if society had been moving away from those unrealistic expectations laid upon moms and women over the age of 35, but maybe not.

Jessica Buwick, a mom on TikTok, found out fairly quickly that people still have interesting ideas about how "old people" should dress when going out in public. The 37-year-old mom ordered a plethora of outfits to try on to wear for her son's graduation, prompted by her seeing other moms on social media dressing much more fancy for graduations than parents did when she graduated.

It was a silly, lighthearted video showing her trying on all of the outfits that did not make the cut for various reasons. One was too short and didn't zip. Another was ill-fitting and confusing. They were obvious catastrophes that just didn't work, so she made the misfortune into funny content. And people had a lot to say.

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Three women, three MS journeys: How multiple sclerosis looks different for everyone

Gina, Nathalie and Helga share their reactions to being diagnosed with MS and how they stay informed and positive in the face of ever-changing symptoms.

Courtesy of Sanofi

Helga, Nathalie and Gina all have MS, and their experiences show how differently the disease can manifest.

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It’s been 155 years since neurologist Jean-Martin Charcot gave the first lecture on a mysterious progressive illness he called “multiple sclerosis.” Since then, we’ve learned a lot. We know MS causes the immune system to attack healthy tissue, including damaging the brain and spinal cord. Resulting symptoms can be debilitating and include fatigue, blurred vision, memory problems and weakness. Huge advancements in our understanding of MS and its underlying causes, as well as treatment advances, have been made in the past few decades, but MS remains a complex and unpredictable reality for the 2.8 million+ people diagnosed around the world.

Ironically, the only real constant for people living with MS is change. There’s no set pattern or standard progression of the disease, so each person’s experience is unique. Some people with MS have mild symptoms that worsen slowly but sometimes improve, while others can have severe symptoms that drastically alter their daily lives.

All people with MS share some things in common, however, such as the need to stay informed on the ever-evolving research, find various lines of support and try to remain hopeful as they continue living with the disease.

To better understand what navigating life with MS really looks like, three women shared their MS stories with us. Their journeys demonstrate how MS can look different for different people and interestingly, how the language used to talk about the disease can greatly impact how people understand their realities.

woman with horse, woman riding horseGina loves riding her horse, Benita.Courtesy of Sanofi

Gina—Hamburg, Germany (diagnosed with relapsing multiple sclerosis in 2017)

When her youngest son was 4 months old, Gina started having problems with her eye. She’d soon learn she was experiencing optic neuritis—her first symptom of MS.

“Immediately after the diagnosis, I looked up facts on MS because I didn’t know anything about it,” Gina says. “And as soon as I knew what could really happen with this disease, I actually got scared.”

As her family’s primary income provider, she worried about how MS would impact her ability to work as a writer and editor. Her family was afraid she was going to end up in a wheelchair. However, for now, Gina’s MS is managed well enough that she still works full-time and is able to be active.

“When I tell somebody that I have MS, they often don't believe me the first time because I don't fulfill any stereotypes,” she says.

Overwhelmed by negative perspectives on living with MS, Gina sought support in the online MS community, which she found to be much more positive.

“I think it’s important to use as many positive words as you can when talking about MS.” It’s important to be realistic while also conveying hope, she says. “MS is an insidious disease that can cause many bad symptoms…that can be frightening, and you can't gloss over it, either.”

To give back to the online community that helped her so much, Gina started a blog to share her story and help others trying to learn about their diagnosis.

Though she deals with fatigue and cognitive dysfunction sometimes, Gina stays active swimming, biking, riding horses and playing with her sons, who are now 11 and 6.

Cognitive dysfunction is common in MS, with over half of people affected. It can impact memory, attention, planning, and word-finding. As with many aspects of MS, some people experience mild changes, while others face more challenges.

Gina says that while there’s still a lot of education about MS needed, she feels positive about the future of MS because there’s so much research being done.

woman in wheelchair holding medal, woman rowingNathalie is an award-winning rower with multiple international titles.Courtesy of Sanofi

Nathalie — Pennes Mirabeau, France (diagnosed with relapsing-remitting multiple sclerosis in 2002)

Nathalie was a teenager and a competitive athlete when she noticed her first symptoms of MS, but it would take four years of “limbo” before she was diagnosed.

“Ultimately, the diagnosis was more of a relief, than a shock,” she says. “Because when you have signs and you don’t know why, it’s worse than knowing, in the end, what you have.”

However, learning more about the disease—and the realities of disease progression—scared her.

“That glimpse of the future was direct and traumatic,” she says. Her neurologist explained that the disease evolves differently for everyone, and her situation might end up being serious or very mild. So, she decided to stop comparing herself to others with MS.

She said to herself, “We’ll see what happens, and you’ll manage it bit by bit.”

By 2005, Nathalie’s MS had progressed to the point of needing a wheelchair. However, that has not dampened her competitive spirit.

Nathalie began her international rowing career in 2009 and has won multiple world titles, including two Paralympic medals—silver in London and bronze in Tokyo. Now, at 42, she still trains 11 times a week. Fatigue can be a problem, and sometimes hard workouts leave her with muscle stiffness and shaking, but she credits her ongoing sports career for helping her feel in tune with her body’s signals.

“Over the years, I’ve learned to listen to my body, letting my body guide when I need to stop and take breaks,” she says.

Nathalie explains that she used to only look backwards because of the initial shock of her diagnosis. In time, she stopped thinking about what she couldn’t do anymore and focused on her future. She now lives in the following mindset: “Even when doors close, don’t miss out on those that open.” Instead of focusing on what she can’t do, she focuses on the opportunities she still has. Right now, this includes her training for the 2024 Paralympic Games in Paris, where she will compete for another rowing medal.

“I only go forward,” she says. “Well, I try, anyway…It’s easy to say, it’s not always easy to do. But that’s what I try to do.”

woman exiting water after swimming, woman with great daneHelga's Great Dane has become a helpful and beloved companion.Courtesy of Sanofi

Helga—Johannesburg, South Africa (diagnosed with relapsing multiple sclerosis in 2010)

When Helga first started having balance issues and numbness in her feet, she chalked it up to her training as a runner. But when the numbness moved to her face, she knew something was wrong. She never guessed it was MS.

“When I was diagnosed, I felt completely overwhelmed and clueless,” Helga says. “I felt that I had nowhere near enough information. I did not know anything about the disease…I had no idea that it was going to be a process of continually monitoring and adjusting your lifestyle.”

In the beginning, Helga’s symptoms developed slowly, and she didn’t appear ill to others. She was even able to run for a few years after her diagnosis, but she couldn’t do marathons anymore, and she began to fall frequently due to balance issues and right-foot dragging. Then her cognition issues became more problematic, especially in her job as a trainer in a printing company.

“My executive function, decision-making and short-term memory were affected to the point that I was eventually medically unfit for work,” she says. She stopped working in 2017.

However, she didn’t stop living life. Even though she could no longer run, she continued to swim competitively. She got a Great Dane puppy and trained him as a service dog to help her walk. She also serves as vice chair of the patient support organization Multiple Sclerosis South Africa, and she advises others who have been diagnosed to join a patient advocacy group as soon as possible to get reliable information and meet others with MS.

Helga says she is “hopeful” about the future of MS. “I must say that I am so grateful that we have all the new medications available, because my life would not be the same if it wasn't for that,” she adds.

Part of how she manages her MS is by looking at the positives.

“If I could tell the world one thing about MS, it would be that MS is an incurable disease of the nervous system, but it's also the greatest teacher of valuing your health, family, friends, and managing change in your life,” she says. “My life is diversified in a way that I never, ever thought it would, and MS has been honestly the greatest teacher.”

Each MS journey is unique – with each person impacted experiencing different struggles, successes, and feelings as they manage this unpredictable disease. But the common thread is clear – there is a critical need for information, support, and hope. We are proud to participate in World MS Day and share these incredible stories of living life while living with MS. To learn more about MS, go to https://www.sanofi.com/why-words-really-matter-when-it-comes-to-multiple-sclerosis.

MAT-GLB-2301642-v1.0-05/2023

This article was sponsored by Sanofi. Participants were compensated when applicable.

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People living to work, not working to live.

If we looked 60 years into the past, there are a lot of things that were accepted as “normal” that today most people find abhorrent. For example, people used to smoke cigarettes everywhere. They’d light up in hospitals, schools and even churches.

People also used to litter like crazy. It’s socially unacceptable now, but if you lived in the ’70s and finished your meal at McDonald’s, you’d chuck your empty styrofoam container (remember those?) and soda cup right out of the window of your car and onto the street.

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Do you think a 10-year-old kid would have any idea how to use a payphone in 2022? Would they be able to use a Thomas Guide map to find out how to get somewhere? If they stepped into a time warp and wound up in 1975, could they throw a Led Zeppelin album on the record player at a party?

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Traveler and content creator Pency Lucero was willing to take that gamble. After thorough research, she stumbled upon an Airbnb in Rörbäck, Sweden with an actual picture of the northern lights shining above the cabin in the listing. With that kind of photo evidence, she felt good about her odds.

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Man makes an extra $10,000 a year renting out his driveway

If you've got the space, why not rent it out?

The Brighton Pier in England

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Joe Gorham, 54, of Brighton, England, told The Mirror that renting out the three parking spaces in front of his home was a low-key way to rake in some passive income with little effort.

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Can't really blame her.

Invisible work,” aka “invisible labor,” was a term coined in 1987 by socialist Arlene Kaplan Daniels to describe unseen, unacknowledged and unpaid work most often performed by women—though in an academic sense, it pertains to all marginalized groups.

The unpaid aspect, Daniels noted, has been a particularly important factor, since in Western society we have come to believe that it isn’t work unless there’s monetary pay involved. This philosophy has a two fold effect. One, even things that are enjoyable and easy are considered work if you receive an income from them. And two, domestic duties like childcare and house cleaning, no matter how arduous they are, are not recognized as work simply because they don’t result in a paycheck.

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That’s why more and more women are making their invisible labor impossible to ignore, be it in lighthearted or more serious ways.
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