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Health

The first pill to treat postpartum depression may be ready this year and it could be a game changer

It's in final approvals with the FDA.

postpartum depression, postnatal depression, ppd treatment
via Freepik

A new mother struggling with postpartum depression.

We may be just months away from having the first-ever pill to help treat postpartum depression (PPD). The drug, called Zuranolone, was developed by Sage Therapeutics and Biogen, two companies out of Cambridge, Massachusetts. The FDA has given the drug’s application priority review and the period ends on August 5, 2023.

Currently, there is only one FDA-approved medication for PPD, Zulresso, which is only available through a 60-hour, one-time infusion and can cost up to $35,000 per treatment.

If the medication is approved, it can also be used to treat major depressive disorder (MDD).


What’s unique about the drug is that it is fast-acting. "We feel a tremendous responsibility to patients with MDD and PPD to deliver a potential new treatment option, which is so desperately needed. Most current approved therapies may take weeks or months to work. We are committed to advancing treatments that could help physicians and patients by addressing depression symptoms quickly," Dr. Laura Gault, chief medical officer at Sage Therapeutics Inc., said in a statement.

Zuranolone causes full remission of clinical depression within 45 days in 53% of women versus 30% who received the placebo, according to the study published in the Journal of the American Medical Association Psychiatry.

The new drug could be a godsend to the 500,000 women who suffer from PPD every year. In these women, what starts as a typical case of the “baby blues” can linger and become more intense and lead to an overwhelming loss of energy, irritability, inability to concentrate or make decisions and thoughts of harming themselves or their babies. It also severely inhibits their ability to care for their newborn child.

Symptoms of PPD can begin as early as during pregnancy and as late as a year after giving birth. In rare cases, it can develop into postpartum psychosis, an extreme mood disorder.

PPD is caused by the intense hormonal changes that happen within a woman’s body before and after giving birth. It can also result from numerous anxieties women feel after giving birth, such as the stress of being a “perfect mother,” the effect that pregnancy has on their bodies, being overtired and a lack of free time.

happy mom, happy baby, postpartum depression

A happy, healthy mother and child.

via Pexels.

Zuranolone could also provide faster relief for people dealing with MDD. In 2020, over 14 million Americans were diagnosed with MDD, which creates a persistent feeling of sadness and a loss of interest in things they used to enjoy. It can also affect their ability to have happy, healthy relationships.

In rare situations, MDD can lead to suicidal ideation. Studies show that MDD accounts for up to 89% of all suicides.

If Zuranolone is approved, it will give doctors another vital tool in improving people’s mental health that can relieve debilitating depression in less time. It will also help countless babies that need extra care in their early days from a loving and healthy mother.

If you or someone you know is having thoughts of suicide, call the Suicide and Crisis Lifeline at 988 for free, confidential support.

Joy

Sorry, Labradors. After 31 years, America has a new favorite dog.

The American Kennel Club has crowned a new favorite.

via Pixabay

A sad-looking Labrador Retriever

The sweet-faced, loveable Labrador Retriever is no longer America’s favorite dog breed. The breed best known for having a heart of gold has been replaced by the smaller, more urban-friendly French Bulldog.

According to the American Kennel Club, for the past 31 years, the Labrador Retriever was America’s favorite dog, but it was eclipsed in 2022 by the Frenchie. The rankings are based on nearly 716,500 dogs newly registered in 2022, of which about 1 in 7 were Frenchies. Around 108,000 French Bulldogs were recorded in the U.S. in 2022, surpassing Labrador Retrievers by over 21,000.

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A Korean mother and her son

A recently posted story on Reddit shows a mother confidently standing up for her family after being bullied by a teacher for her culture. Reddit user Flowergardens0 posted the story to the AITA forum, where people ask whether they are wrong in a specific situation.

Over 5,600 people commented on the story, and an overwhelming majority thought the mother was right. Here’s what went down:

“I (34F) have a (5M) son who attends preschool. A few hours after I picked him up from school today, I got a phone call from his teacher,” Flowergardens0 wrote. “She made absolutely no effort to sound kind when she, in an extremely rude and annoyed tone, told me to stop packing my son such ‘disgusting and inappropriate’ lunches."

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Joy

An 8-year-old snuck his handwritten book onto a library shelf. Now it has a 56-person waiting list.

Dillon Helbig's 81-page graphic novel— written by "Dillon His Self"—captured the hearts of his local librarians and their patrons.

Dillon Helbig's 81-page graphic novel captured the hearts of his local librarians.

Writing a book is no easy task, even for adult professional writers. Many would-be authors dream of a day when their work can be found on library shelves, unsure if it will ever come.

But for 8-year-old Dillon Helbig, that day has already arrived—in truly unconventional fashion—thanks to his own determination to make it happen.

Dillon wrote his 81-page graphic novel, "The Adventures of Dillon Helbig's Crismis" (written by "Dillon His Self") in a hardcover journal with colored pencils over the course of a few days. He even put a label on the back of the book that reads "Made in Idho" [sic] and put an illustrated spine label on it as well. Then, without telling anyone, he brought it to his local library in Boise, Idaho, and slipped it in among the books in the children's section.

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Pop Culture

Kelly Clarkson correctly pronouncing a guest's name on her show seems simple but it speaks volumes

Viewers appreciated how respectfully Clarkson handled her interview with K-pop group TWICE when she asked performer Tzuyu how to properly pronounce her name.

The Kelly Clarkson Show/Youtube

It really is as simply as that.

What’s in a name?

A lot, actually. We know that names reflect certain aspects of one’s identity. We know that repeated mispronunciation of a person’s name potentially undermines that identity. We know that sometimes this is unintentional, and other times, more insidious intentions of “othering” are at play. Especially when it comes to those with non-English names.

We also know that, on the flip side, making the effort to properly pronounce a person’s name is one of the simplest forms of kindness and respect that someone can offer. And it really pays dividends.

Just take a page from Kelly Clarkson’s book.
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Pop Culture

Woman shares 5 questions to ask potential employers and people are taking notes

"Being in both senior leadership and directly involved in candidate recruitment, these questions are fire. 10/10 recommend."

TikTok creator gives people 5 questions to ask potential employers.

You know the end of the interview where they ask, "Do you have any questions for us?" It's a dreaded question for a lot of people. Even though you know it's coming, the question still catches you off guard and you wind up asking something possibly irrelevant or nothing at all. Then the whole ride home, approximately fifteen questions pop into your head.

But don't you fret, because TikTok creator Kyyah Abdul has a list of five questions to keep tucked in your brain's pocket to close out an interview. And folks in the comments are applauding the creator's ability to figure out if the company is a fit for you and clarify any concerns the interviewer may have. Her advice was so genius that even a person who is involved in candidate recruitment chimed in saying, "Being in both senior leadership and directly involved in candidate recruitment, these questions are fire. 10/10 recommend."

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@morgvn.elizabeth/TikTok

Hip-hop Irish dancing is kind of the coolest thing ever.

If you somehow missed Irish dance extraordinaire and viral sensation Morgan Bullock, you’re in for a treat.

Back in 2020, the then 20-year-old performer posted a video of her jigging to a remixed version of Megan Thee Stallion’s “Savage,” also featuring the vocals of Beyoncé. As the internet is wont to fawn over unexpected mashups, it’s no wonder that the clip sent folks into a frenzy online.

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