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Health

The first pill to treat postpartum depression may be ready this year and it could be a game changer

It's in final approvals with the FDA.

postpartum depression, postnatal depression, ppd treatment
via Freepik

A new mother struggling with postpartum depression.

We may be just months away from having the first-ever pill to help treat postpartum depression (PPD). The drug, called Zuranolone, was developed by Sage Therapeutics and Biogen, two companies out of Cambridge, Massachusetts. The FDA has given the drug’s application priority review and the period ends on August 5, 2023.

Currently, there is only one FDA-approved medication for PPD, Zulresso, which is only available through a 60-hour, one-time infusion and can cost up to $35,000 per treatment.

If the medication is approved, it can also be used to treat major depressive disorder (MDD).


What’s unique about the drug is that it is fast-acting. "We feel a tremendous responsibility to patients with MDD and PPD to deliver a potential new treatment option, which is so desperately needed. Most current approved therapies may take weeks or months to work. We are committed to advancing treatments that could help physicians and patients by addressing depression symptoms quickly," Dr. Laura Gault, chief medical officer at Sage Therapeutics Inc., said in a statement.

Zuranolone causes full remission of clinical depression within 45 days in 53% of women versus 30% who received the placebo, according to the study published in the Journal of the American Medical Association Psychiatry.

The new drug could be a godsend to the 500,000 women who suffer from PPD every year. In these women, what starts as a typical case of the “baby blues” can linger and become more intense and lead to an overwhelming loss of energy, irritability, inability to concentrate or make decisions and thoughts of harming themselves or their babies. It also severely inhibits their ability to care for their newborn child.

Symptoms of PPD can begin as early as during pregnancy and as late as a year after giving birth. In rare cases, it can develop into postpartum psychosis, an extreme mood disorder.

PPD is caused by the intense hormonal changes that happen within a woman’s body before and after giving birth. It can also result from numerous anxieties women feel after giving birth, such as the stress of being a “perfect mother,” the effect that pregnancy has on their bodies, being overtired and a lack of free time.

happy mom, happy baby, postpartum depression

A happy, healthy mother and child.

via Pexels.

Zuranolone could also provide faster relief for people dealing with MDD. In 2020, over 14 million Americans were diagnosed with MDD, which creates a persistent feeling of sadness and a loss of interest in things they used to enjoy. It can also affect their ability to have happy, healthy relationships.

In rare situations, MDD can lead to suicidal ideation. Studies show that MDD accounts for up to 89% of all suicides.

If Zuranolone is approved, it will give doctors another vital tool in improving people’s mental health that can relieve debilitating depression in less time. It will also help countless babies that need extra care in their early days from a loving and healthy mother.

If you or someone you know is having thoughts of suicide, call the Suicide and Crisis Lifeline at 988 for free, confidential support.

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Family

New study shows spanking hurts kids' mental health and is less effective at teaching lessons

Why is it wrong to hit an adult or an animal but OK to spank a child?

Photo by Kat J on Unsplash

Yet another study shows that spanking isn't good for kids.

Whether to spank your child or not is one of the oldest debates among parents. Many live by the age-old wisdom that to “spare the rod” is to “spoil the child,” while others believe it’s wrong to resort to violence to punish a child when so many alternatives exist.

It also begs the question: If it's wrong to hit your spouse or pet, why is it acceptable to hit a defenseless child?

The 2021 American Family Study found that support for spanking has declined in the U.S. over the past few years. In 2015, 54% either somewhat or strongly agreed with the practice, but that number dropped to 47% in 2021. Thirty-five percent of respondents disagree with the practice and 18% neither agree nor disagree.

A new research study from the Parent and Family Research Alliance in Australia led by Professor Sophie Havighurst and Professor Daryl Higgins from Australian Catholic University makes a strong case that people should stop using corporal punishment to discipline their kids. The study “Corporal punishment of children in Australia: The evidence-based case for legislative reform” analyzed countless studies on the topic and found spanking ineffective and harmful.

The study was published to urge lawmakers to make corporal punishment in Australia illegal. Sixty-five states across the world have made corporal punishment illegal, protecting 14% of the world’s children.

The study defined corporal punishment of children as using physical force to cause pain, but not injury, to correct or control a child’s behavior.

The most startling meta-analysis published in the study found that "only 1 out of 111 statistically significant effect sizes was associated with a link between 'spanking' and a positive child outcome," while 110 were found to be associated with adverse outcomes.

The one positive outcome was in a 1972 study of children of the U.S. military living in West Germany that found those spanked showed less amphetamine and opiate use as adults.

However, the remaining 110 significant results found that spanking had adverse effects, including: “reducing trust and connection with those they are closest to, lower self-esteem, more internalizing and externalizing behavior problems including aggression, mental health difficulties, and increased risk for later substance abuse, antisocial behavior, and violence.”

A meta-analysis found that when children are spanked, they are less likely to internalize the moral implications of the behaviors that led them to be disciplined. It also found that non-physical discipline was more effective at teaching “alternative behaviors,” “developing a child’s conscience,” and advancing their “emotional development.”

Another meta-analysis cited in the story found that corporal punishment in childhood was associated with mental health problems, low self-esteem and antisocial behavior.

In the end, the studies show that corporal punishment is counter-productive when it comes to raising healthy, happy children. But it will take much more than a study to get people to reconsider their views of corporal punishment because they are deeply rooted in many cultural traditions.

Looking for some non-physical alternatives to discipline your child? Here’s a great place to start from WebMD.

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