How a simple blood test could improve life for more than half of depression patients.

If you've tried antidepressants to treat your depression, you probably already know this, but finding the right one can be a trial.

There are many different antidepressants out there today, and each works differently. Photo from Joe Raedle/Getty Images.


About 1 in 5 Americans will experience major depression during their lifetime. Antidepressant medication, either alone or in combination with things like cognitive behavior therapy or exercise, can be a powerful tool to help people live with depression — if it works.

Unfortunately, the go-to antidepressants don't work for more than half of the people who try them.

And about a third of all patients never find their perfect fit. This lack of response to the medication isn't anyone's fault — our bodies just work differently. But if you're looking to get help and worry about finding the right medication, a pretty amazing new tool could help.

If you've gone through this, you know the trial and error process can be physically, mentally, and emotionally taxing. It can mean weeks or months of wondering what each new thought means: whether those couple of sleepless nights are a new side effect or just run-of-the-mill insomnia; whether the medication is having any effect at all.

Is this a side effect or just restlessness? At 3 a.m., the line can be hard to see. Image from iStock.

Wouldn't it be awesome if we could skip some of that trial and error?

That's what a group of researchers in England is working on. Their research was just published in The International Journal of Neuropsychopharmacology.

Their idea is a premedication blood test that would help find the right medication faster.

Image from iStock.

Over the past few years, scientists have been figuring out more and more about how depression affects our bodies. This new blood test measures the level of two biomarkers — or chemical signals — that have previously been linked to poor medication responses.

What they found is that different people had different levels of these biomarkers. If you were above a certain threshold, you had a 99% chance that the go-to meds wouldn't work for you. With this test, these people could save the time they would have spent in the past trying meds that would never work for them to begin with.

This new test could help more than half of the people who suffer from depression jump weeks — or even months — ahead in their treatment.


Image from iStock.

It's not a crystal ball — patients and psychiatrists would still need to work together to figure out the specifics — but instead a frustrating period of trial and error, some patients could skip straight to different medications, combinations, or non-medication-based treatments altogether.

This might sound like a simple thing, but if you've gone through those weeks of trial and error yourself, you know how much a relief this would be.

Brian Dow of the nonprofit Rethink Mental Illness was reported by The Independent as saying, "We hope this new research creates a much needed shortcut to a future where it's no longer luck of the draw when it comes to vital medication."

The next step is to take this from proof-of-concept to clinical trial.

Now that the science seems to back up the idea, the next step for scientists is to actually try it out in a clinical setting and see if it truly does work better than current methods.

In the future, treating depression could become easier and faster, helping people avoid the hassle of trial and error and letting them focus on the most important thing: getting healthy.

Photo by Louis Hansel on Unsplash
True

This story was originally shared on Capital One.

Inside the walls of her kitchen at her childhood home in Guatemala, Evelyn Klohr, the founder of a Washington, D.C.-area bakery called Kakeshionista, was taught a lesson that remains central to her business operations today.

"Baking cakes gave me the confidence to believe in my own brand and now I put my heart into giving my customers something they'll enjoy eating," Klohr said.

While driven to launch her own baking business, pursuing a dream in the culinary arts was economically challenging for Klohr. In the United States, culinary schools can open doors to future careers, but the cost of entry can be upwards of $36,000 a year.

Through a friend, Klohr learned about La Cocina VA, a nonprofit dedicated to providing job training and entrepreneurship development services at a training facility in the Washington, D.C-area.

La Cocina VA's, which translates to "the kitchen" in Spanish, offers its Bilingual Culinary Training program to prepare low-and moderate-income individuals from diverse backgrounds to launch careers in the food industry.

That program gave Klohr the ability to fully immerse herself in the baking industry within a professional kitchen facility and receive training in an array of subjects including culinary skills, food safety, career development and English language classes.

Keep Reading Show less

This article originally appeared on 12.02.19


Just imagine being an 11-year-old boy who's been shuffled through the foster care system. No forever home. No forever family. No idea where you'll be living or who will take care of you in the near future.

Then, a loving couple takes you under their care and chooses to love you forever.

What could one be more thankful for?

That's why when a fifth grader at Deerfield Elementary School in Cedar Hills, Utah was asked by his substitute teacher what he's thankful for this Thanksgiving, he said finally being adopted by his two dads.

via OD Action / Twitter

To the child's shock, the teacher replied, "that's nothing to be thankful for," and then went on a rant in front of 30 students saying that "two men living together is a sin" and "homosexuality is wrong."

While the boy sat there embarrassed, three girls in the class stood up for him by walking out of the room to tell the principal. Shortly after, the substitute was then escorted out of the building.

While on her way out she scolded the boy, saying it was his fault she was removed.

RELATED: A gay couple's pride flag helped give a young teen the courage to come out to their family

One of the boy's parents-to-be is Louis van Amstel, is a former dancer on ABC's "Dancing with the Stars." "It's absolutely ridiculous and horrible what she did," he told The Salt Lake Tribune. "We were livid. It's 2019 and this is a public school."

The boy told his parents-to-be he didn't speak up in the classroom because their final adoption hearing is December 19 and he didn't want to do anything that would interfere.

He had already been through two failed adoptions and didn't want it to happen again.

via Loren Javier / Flickr

A spokesperson for the Alpine School District didn't go into detail about the situation but praised the students who spoke out.

"Fellow students saw a need, and they were able to offer support," David Stephenson said. "It's awesome what happened as far as those girls coming forward."

RELATED: A homophobic ad was placed next to a pizza shop. They messed with the wrong place.

He also said that "appropriate action has been taken" with the substitute teacher.

"We are concerned about any reports of inappropriate behavior and take these matters very seriously," Kelly Services, the school the contracts out substitute teachers for the district, said in a statement. "We conduct business based on the highest standards of integrity, quality, and professional excellence. We're looking into this situation."

After the incident made the news, the soon-to-be adoptive parents' home was covered in paper hearts that said, "We love you" and "We support you."

Religion is supposed to make us better people.

But what have here is clearly a situation where a woman's judgement about what is good and right was clouded by bigoted dogma. She was more bothered by the idea of two men loving each other than the act of pure love they committed when choosing to adopt a child.