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This British organization asked for beautiful science photos. Here are 13 finalists.

When David Linstead was about 9 or 10, he pestered his parents for a microscope.

It sparked a lifetime of scientific curiosity. David is now a retired research scientist with over 20 years of experience. In 2016, he captured an incredible slice of life in a microscopy photo that borders on fine art. The blue hues and fluorescent oranges and pinks burst through in a kaleidoscope of colors. To the uninformed eye, this image could be seen as evidence of alien life. But it's actually a photo of cat skin with hair and whiskers.

A polarized light micrograph of a section of cat skin, showing hairs, whiskers, and their blood supply. This sample is from a Victorian microscope slide. Blood vessels were injected with a red dye called carmine dye (here appearing black) in order to visualize the capillaries in the tissue, a newly developed technique at the time. This image is a composite made up of 44 individual images stitched together to produce a final image 12 millimeters wide. Image via David Linstead/Wellcome Image Awards.


The Wellcome Image Awards have been highlighting amazing images like this one for 20 years. This year's 22 finalists were chosen from photographs, illustrations, and other visual renderings from the sciences that showcase the beauty in their fields.

Here are 12 more images from this year's finalists that show the beauty behind science.

1. Hawaiian bobtail squid.

Image via Mark R Smith, Macroscopic Solutions/Wellcome Image Awards.

Native to the Pacific Ocean, Hawaiian bobtail squid are nocturnal predators that remain buried under the sand during the day and come out to hunt for shrimp near coral reefs at night. The squid have a light organ on their underside that houses a colony of glowing bacteria called Vibrio fischeri. The squid provide food and shelter for these bacteria in return for their bioluminescence.

2. Language pathways of the brain.

Image via Stephanie J Forkel and Ahmad Beyh, Natbrainlab, King’s College London; Alfonso de Lara Rubio, King’s College London/Wellcome Image Awards.

The brain is composed of two types of matter. Gray matter contains cells and is responsible for processing information. White matter connects these areas of grey matter, allowing information to be transferred between distant areas of the brain. Areas responsible for speech and language have been mapped to two different brain regions. This image shows a 3D-printed reconstruction of the white matter pathway connecting these two areas (here shown from the left), which is called the arcuate fasciculus.

3. Surface of a mouse retina.

Image via Gabriel Luna, Neuroscience Research Institute, University of California, Santa Barbara/Wellcome Image Awards.

The retina, located at the back of the eye, contains light-sensitive cells responsible for converting light into electrical nerve signals that the brain can process. As a result of aging or injury, the retina can lose this function, causing vision loss. This image was created by digitally stitching together over 400 images to form one large image, so as to show the entire surface of a mouse retina.

4. Vessels of a healthy mini-pig eye.

Image via Peter M Maloca, OCTlab at the University of Basel and Moorfields Eye Hospital, London; Christian Schwaller; Ruslan Hlushchuk, University of Bern; Sébastien Barré/Wellcome Image Awards.

A 3D model of a healthy mini-pig eye. The dent on the right side of the image is the pupil, the opening that allows light into the eye. The blood vessels shown are bringing energy and food to the muscles surrounding the iris, which controls the amount of light entering the eye. The smallest vessels seen here are 20–30 micrometers (0.02–0.03 millimeters) in diameter. The other large vessels are feeder vessels for the retina, the light-sensing region at the back of the eye.

5. The placenta rainbow.

Image via Suchita Nadkarni, William Harvey Research Institute, Queen Mary University of London/Wellcome Image Awards.

The placenta rainbow highlights differences in mouse placental development that can result from manipulation of the mother’s immune system. These placentas were investigated at day 12 of the 20-day gestation period — the point at which a mouse’s placenta has gained its characteristic shape but is still developing.

6. Developing spinal cord.

Image via Gabriel Galea, University College London/Wellcome Image Awards.

Our spines allow us to stand and move, and they protect the spinal cord, which connects all the nerves in our body with our brain. The spinal cord is formed from a structure called the neural tube, which develops during the first month of pregnancy.

This series of three images shows the open end of a mouse’s neural tube, with each image highlighting (in blue) one of the three main embryonic tissue types. On the left is the neural tube itself, which develops into the brain, spine, and nerves. On the right is the surface ectoderm — the word "ectoderm" comes from the Greek ektos meaning "outside" and derma meaning skin — which will eventually form the skin, teeth, and hair. The middle image shows the mesoderm (also from Greek, meaning "middle skin"), which will form the organs.

7. Zebrafish eye and neuromasts.

Image via Ingrid Lekk and Steve Wilson, University College London/Wellcome Image Awards.

This four-day-old zebrafish embryo has been modified using two mechanisms — borrowed from the fascinating worlds of bacteria and yeast — that are widely applied in genetics research. A DNA-editing technology called CRISPR/Cas9 was used to insert a gene called Gal4 next to the gene that the researchers wished to study. These Gal4 fish were then bred with special reporter fish to create fish where the gene of interest displays red whenever it is activated.

8. Intraocular lens "iris clip."

Image via Mark Bartley, Cambridge University Hospitals NHS Foundation Trust/Wellcome Image Awards.

This image shows how an "iris clip," also known as an artificial intraocular lens, is fitted onto the eye. An iris clip is a small, thin lens made from silicone or acrylic material with plastic side supports to hold it in place. An iris clip is fixed to the iris through a three-millimeter surgical incision and is used to treat conditions such as myopia (nearsightedness) and cataracts (cloudiness of the lens). This particular patient, a 70-year-old man, regained almost full vision following his surgery.

9. #BreastCancer Twitter connections.

Image via Eric Clarke, Richard Arnett and Jane Burns, Royal College of Surgeons in Ireland/Wellcome Image Awards.

This is a graphical visualization of data extracted from tweets containing the hashtag #BreastCancer. Twitter users are represented by dots, called nodes, and lines connecting the nodes represent the relationships between the Twitter users. Nodes are sized differently according to the number and importance of other nodes they are connected with, and the thickness of each connecting line is determined by the number of times that a particular relationship is expressed within the data.

The "double yolk" structure at the top of the image indicates common mentions of two accounts. This area of the graph provides a graphical expression of trending data in Twitter, as it represents one tweet that was retweeted thousands of times.

10. Brain-on-a-chip.

Image via Collin Edington and Iris Lee, © Massachusetts Institute of Technology (MIT)/Wellcome Image Awards.

Neural stem cells have the ability to form all the different cell types found in the nervous system. Here, researchers are investigating how neural stem cells grow on a synthetic gel called PEG. After just two weeks, the stem cells (magenta) produced nerve fibers (green). These fibers grew away from the cell due to chemical gradients in the gel, teaching researchers about how their environment affects their structural organization.

11. MicroRNA scaffold cancer therapy.

Image via João Conde, Nuria Oliva and Natalie Artzi, Massachusetts Institute of Technology (MIT)/Wellcome Image Awards.

Researchers are investigating short genetic sequences called microRNAs, which control the proper function and growth of cells, as a possible cancer therapy. However, their potential use is limited by the lack of an efficient system to deliver these microRNAs specifically to cancerous cells. Researchers at the Massachusetts Institute of Technology have developed such a system, combining two microRNAs with a synthetic polymer to form a stable woven structure that is a bit like a net. This synthetic net can coat a tumor and deliver the two microRNAs locally to cancer cells.

12. Unravelled DNA in a human lung cell.

Image via Ezequiel Miron, University of Oxford/Wellcome Image Awards.

In order for plants and animals to grow and remain healthy, cells need to have the ability to replicate. During cell division, also known as mitosis, the entire DNA content of the cell is copied, with half going to each new cell. DNA is found in the nucleus, which acts a bit like the brain.

This picture shows the nucleus of one of two new daughter cells. The DNA in this cell has somehow become caught and is being pulled between the two cells. This has caused the DNA to unfold inside the nucleus, and DNA fibers can be seen running through it. As the new cells have moved apart, the tension distributed by the rope-like DNA has deformed the nucleus’ usually circular envelope.

There they are, in all their majesty.

Looking at the sheer brilliance of these images, it's easy to see why funding for science is fundamentally important to society. They show the value of science to better understand our world by revealing the quiet beauty behind the universe's veil. That's the power of scientific exploration.

To learn more about the Wellcome Image Awards and see all of this year's and previous years' winners, visit their website. All caption info via Wellcome Image Awards.

Pop Culture

'Wicked' author says one line in 'The Wizard of Oz' inspired Elphaba and Glinda's backstory

Gregory Maguire says he "fell down to the ground" laughing when the idea hit him.

Public domain

The two witches in "The Wizard of Oz" clearly had a history together.

Have you ever watched a movie or read a book or listened to a piece of music and wondered, "How did they come up with that idea?" The creative process is so enigmatic even artists themselves don't always know where their ideas come from, so It's a treat when we get to hear the genesis of a brilliant idea straight from the horse's mouth. If you've watched "Wicked" and wondered where the idea for the friendship between Elphaba (the Wicked Witch) and Glinda (the Good Witch) came from, the author of the book has shared the precise moment it came to him.

The hit movie "Wicked" is based on the 20-year-old hit stage musical, which is based on the novel "Wicked: The Life and Times of the Wicked Witch of the West" written by Gregory Maguire. While the musical is a simplified version of the 1995 book, the basic storyline—the origin story of the two witches from "The Wizard of Oz"—lies at the heart of both. In an interview with BBC, Maguire explained how Elphaba and Glinda's friendship popped into his head.

 

Maguire was visiting Beatrix Potter's farm in Cumbria, England, and thinking about "The Wizard of Oz," which he had loved as a child and thought could be an interesting basis for a story about evil.

"I thought 'alright, what do we know about 'The Wizard of Oz' from our memories,'" he said. "We have the house falling on the witch. What do we know about that witch? All we know about that witch is that she has feet. So I began to think about Glinda and the Wicked Witch of the West…

 glinda, elphaba, wicked,  In "Wicked," the two Oz witches met as students at Shiz University.  Giphy GIF by Wicked 

"There is one scene in the 1939 film where Billie Burke [Glinda the Good Witch] comes down looking all pink and fluffy, and Margaret Hamilton [the Wicked Witch of the West] is all crawed and crabbed and she says something like, 'I might have known you'd be behind this, Glinda!' This was my memory, and I thought, now why is she using Glinda's first name? They have known each other. Maybe they've known each other for a long time. Maybe they went to college together. And I fell down onto the ground in the Lake District laughing at the thought that they had gone to college together."

In "Wicked," Glinda and the Wicked Witch, Elphaba, meet as students at Shiz University, a school of wizardry. They get placed as roommates, loathe each other at first, but eventually become best friends. The story grows a lot more complicated from there (and the novel goes darker than the stage play), but it's the character development of the two witches and their relationship with one another that force us to examine our ideas about good and evil.

  - YouTube  youtu.be  

 

Maguire also shared with the Denver Center for Performing Arts what had inspired him to use the "Wizard of Oz" characters in the first place.

"I was living in London in the early 1990’s during the start of the Gulf War. I was interested to see how my own blood temperature chilled at reading a headline in the usually cautious British newspaper, the Times of London: 'Sadaam Hussein: The New Hitler?' I caught myself ready to have a fully formed political opinion about the Gulf War and the necessity of action against Sadaam Hussein on the basis of how that headline made me feel. The use of the word Hitler – what a word! What it evokes! When a few months later several young schoolboys kidnapped and killed a toddler, the British press paid much attention to the nature of the crime. I became interested in the nature of evil, and whether one really could be born bad. I considered briefly writing a novel about Hitler but discarded the notion due to my general discomfort with the reality of those times. But when I realized that nobody had ever written about the second most evil character in our collective American subconscious, the Wicked Witch of the West, I thought I had experienced a small moment of inspiration. Everybody in America knows who the Wicked Witch of the West is, but nobody really knows anything about her. There is more to her than meets the eye."

 wizard of oz, wicked witch of the west The Wicked Witch of the West has a story of her own.  Giphy  

Authors and artists—and their ideas—help hold a mirror up to humanity for us to see and reflect on who we are, and "Wicked" is one of those stories that makes us take a hard look at what we're seeing in that mirror. Thanks, Gregory Maguire, for launching us on a collective journey that not only entertains but has the potential to change how we see one another.

This story originally appeared last year.

via Josie Bowers / TikTok

Josie Bowers, a 19-year-old woman from Canada, shared the story of how she thwarted an intruder when she was 15. The viral TikTok video is a harrowing tale and a valuable lesson for everyone to learn. Josie was staying with her family at the Ocean City Hilton in Ocean City, Maryland, when the incident occurred.

She went to her hotel room alone to take a shower while her family was on the beach. After getting out of the shower, she was alarmed when she noticed a long wire with a hook at the end wiggling its way out of the crack at the bottom of the front door. The hook was waving around, trying to catch the handle to open the door. It's amazing that no one in the hallway noticed the incredibly suspicious activity.

The intruders eventually caught the handle with the wire and pulled it down to enter the room. Without hesitation, Josie slammed the door shut and put on the deadbolt. "My main thought was holy sh*t, I'm in a towel right now and someone is about to break in and get me," she said on TikTok. "So the door opens a crack, and I just slammed it back shut and put the deadbolt on."

After the door was shut on the intruders, they pretended to work for the hotel. "So they tell me your keycard is broken and we need to get into the room and fix your keypad for you," she continued. "And so I open the door a tad bit, to see if it was a worker. It clearly wasn't, they were in jeans and a T-shirt. Hilton keeps it pretty classy, not the attire."

@josiebowers10

Reply to @emmade1rey #part2

Josie then remembered a trick that her stepfather, who's a police officer, once told her: Never let people know you're alone.

"I yelled 'Hey dad, there's someone here to fix the door.' As soon as they thought that I wasn't alone – and potentially my dad was there – they ran, they were gone," she said. A lot of people freeze in such a stressful situation but Josie was able to remember her stepfather's advice and it made all the difference.

Given their reaction, it's pretty clear that the intruders must have followed her up from the beach or had some inside information to know that she was alone. They didn't want anything to do with her father. "So I think I'm very smart for this one, my stepdad is a police officer, he taught me never to let people know you're alone. I yelled 'Hey dad, there's someone here to fix the door.' As soon as they thought that I wasn't alone, and potentially my dad was there. They ran, they were gone," she said.

@josiebowers10

Reply to @lionacreates #part3 #oceancity

The TikTokker shared the video to show others what they should do in a similar situation and to remind them to never let anyone know they are alone.

"I'm glad I had this experience so I can teach people about it. Obviously, I'm safe but it could have ended up a lot worse," she said. "Be safe, you can get door stoppers, always put on the deadbolt."


This article originally appeared four years ago.

via James Breakwell/X

All parents have had similar convos with thier kiddos.

Raising kids is tough, but there's a lot of laughs along the way. Especially when actual conversations start, as kids begin trying to make sense out of the world around them, ask questions, and test mommy and daddy's resolve.

Back in 2018, comedy writer and children's book author James Breakwell, with four daughters who were all under the age of eight at the time, shared their hilarious conversations on X. From these tweets, it looks like comedy runs in the family. Here's a sampling of some Breakwell's funniest kid-inspired tweets.

 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 


 

While Breakwell's 7-year-old wasn't as heavily featured, when she was quoted, the sarcasm was palpable. Which makes sense, considering that kiddos begin understanding this mechanism around that age.

 


 


 


 


 


 


 


 


 


 


 


 


 

Kids really do say the darnedest things, and we love them for it. It one of the many, many ways then bring so much joy to the world. It almost makes up for the headaches and sleepless nights, doesn't it.

This article originally appeared seven years ago.

Remember things being built to last?

Americans are well aware of shrinkflation, where food companies reduce the sizes of their products while the price remains the same at the grocery store. You see this in fast food restaurants when you pick up a burger and feel like your hand has grown a few inches, and at the supermarket when you buy a box of cookies, it weighs less than it did a few weeks ago. Companies use this strategy when they think you’ll be less likely to notice a dip in quantity than a hike in the price.

We see something similar in the world of retail, particularly fast fashion. Fast fashion offers cheaper garments made from low-quality materials that last about as long as the trend does, so people can throw them away and buy the next hot thing. This can be a real problem because fast fashion harms the environment and leads to exploitative labor practices. And the tough part is—even for the most conscious of consumer, it's hard to escape from.

Here's a prime example of what this looks like in the real world. A few months ago, a TikTokker named Tom (@SideMoneyTom), popular for making videos about consumer products, went viral for a video where he called out shoe manufacturers for dropping their quality while keeping prices high. “So many of you guys want to shoot the messenger, but look, it's not my fault shoes are made out of Styrofoam and oil now,” Tom says in a TikTok with over 528,000 views. “It's literally every shoe you look at now. It's not even just the cheap ones. I can find hundred dollar plus pairs of shoes all day long with glue squeezing out of their Styrofoam cracks.”

 
 @sidemoneytom Replying to @Oscar Magaña shoes are done #fyp #shoes #foryou ♬ original sound - SideMoneyTom 
 
 

Tom notes that recently, shoes have been made with foam soles instead of rubber. Both have pros and cons. Foam is a little more comfortable, but rubber lasts a lot longer. Rubber shoes keep shape and support over time and are much more durable. Conversely, foam shoes compress over time, losing their support and comfort. When companies sell cheaper shoes that wear out more quickly, they make much more money because you must keep replacing them.

In the video, Tom adds that many companies that used to have shoes made with rubber heels, such as Carhartt and Timberland, have switched to foam. This is an interesting choice for brands that pride themselves on selling durable products.

Cora Harrington, a writer and lingerie expert, says that companies aren't entirely to blame. Americans don’t want to pay higher prices. “People don’t exactly want to pay more for all that stuff,” Harrington told Vox. "So what has to happen if everything is more expensive and the customers still want to pay the same price, something has to be cut and that’s often going to be the quality of the garment.”

“There is an entire generation of consumers at this point that doesn’t actually know what high-quality clothing feels like and looks like,” Harrington continues. “It gets easier, I think, for consumers to just not know any better.”

Many commenters have noticed the decline in shoe quality and praised Tom for pointing it out. "I am so happy I’m not the only one who is baffled by shoes being made of styrofoam and then being upcharged for them," one commenter wrote. "When shoes started being named some version of 'Air Light Cloud float,' my thought was it was because they went from quality rubber to cheap foam and less materials,” another commenter added.

Tom believes the decline in shoe quality is an example of a more significant trend affecting American consumers' products: quality is decreasing while prices remain the same. “The quality of everything is going to hell, and the prices are going up," Tom concludes his video. "The problem is, so many of us have just become used to it that we keep buying it, and we basically allow them to dumb down the quality of everything. Everything in our lives. These shoes are just the tip of the iceberg. Start thinking about it in your life. What are you gonna allow to be garbage quality?"

This article originally appeared in March.

Boomer panic is real.

In a video posted in September 2023, TikToker @myexistentialdread used the phrase “boomer panic” to explain how baby boomers (1946 to 1964) can quickly become unhinged when faced with the most minor problems. It all started when she visited a Lowe’s hardware store and encountered a boomer-aged woman working at the check-out stand.

“I had a dowel that didn’t have a price tag on it, whatever, so I ran back and took a photo of the price tag. And as I was walking back towards her, I was holding up my phone… because I had multiple dowels and that was the one that didn’t have the price tag on it,” she said in the video. “And she looks at me and she goes, ‘I don’t know which one that is,’ and she starts like, panicking.” The TikToker said that the woman was “screechy, panicking for no reason.”

 older woman upset, boomer reactions, boomer panic Older people can become frustrated over seemingly small things.Photo credit: Canva

Many people raised by boomers understood what she meant by "boomer panic." "Boomer panic is such a good phrase for this! Minor inconvenience straight to panic," the most popular commenter wrote. And while there was some unfortunate boomer-bashing in the comments, some younger people tried to explain why the older folks have such a hard time regulating their emotions: “From conversations with my mother, they weren’t allowed to make mistakes and were harshly punished if they did.” The TikToker responded, “A lot of people mentioned this, and it breaks my heart. I think you’re right,” Myexistentialdread responded.

A follow-up video by YourTango Editor Brian Sundholm tried to explain boomer panic in an empathetic way.

 

“Well, it's likely that there actually was a reason the woman started panicking about a seemingly meaningless problem,” Sundholm said. “Most of us nowadays know the importance of recognizing and feeling our emotions.” Sundholm then quoted therapist Mitzi Bachman, who says that when people bottle up their emotions and refuse to express them, it can result in an "unhinged" reaction.

TikToker Gabi Day shared a similar phenomenon she noticed with her boomer mom; she called the behavior “anxiety-at-you.”

Day’s boomer mother was “reactive,” “nervous,” and “anxious” throughout her childhood. Now, she is still on edge with Day’s children. “She's immediately like gasping and just really like exaggerated physical reactions, and then, of course, that kind of startles my kid,” Day said. “Again, I know that this comes from a place of care. It's just a lot,” she continued.

@itsgabiday

It comes from a place of love but it is exhausting 🫠😬 #millennialmomsoftiktok #boomergrandma #reparenting #gentleparenting

 

There is a significant difference in emotional intelligence and regulation between how boomers were raised and how younger generations, such as Gen X, millennials, and Gen Z, were brought up. Boomers grew up when they had to bottle up their feelings to show their resilience. This can lead to growing anger, frustration with situations and people, chronic stress, and anxiety—all conditions that can lead to panicky, unhinged behavior.

Ultimately, Sundholm says that we should sympathize with boomers who have difficulty regulating their emotions and see it as an example of the great strides subsequent generations have made in managing their mental health. “It may seem a little harsh to call something 'boomer panic,' but in the context of how many of them were raised, it makes a lot of sense,” Sundholm says. “It also underlines the importance of emotional regulation skills and teaching them to future generations. And maybe most important, having compassion for those who never had a chance to learn them.”

 older person's hands holding a younger person's hands, compassion for elderly Having compassion for older generations can go a long way.Photo credit: Canva

This article originally appeared in March.