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Heroes

This doctor saw AIDS firsthand in its darkest hour. Now he's helping make an HIV vaccine.

Dr. Anthony Fauci remembers the first AIDS patient he ever met.

Fauci at a conference in 2015. Photo from Bluerasberry/Wikimedia Commons.

It was 1981. A young man walked into Fauci's office. He was very sick and getting worse. Among his other maladies, an opportunistic infection was attacking his retinas — the man was going blind right in front of Fauci. But there wasn't anything Fauci could do for him.

At the time, doctors didn't even know what AIDS was. It would be a year before the term was even invented.

"It was a very painful and very frustrating because, you know, when you're a physician you're trained as a healer," said Fauci. But he couldn't heal this young man. The patient eventually died of the disease.

"That was the first of several thousand patients I've seen over the last 35 years," Fauci said.

But Fauci didn't give up.

Now, more than 30 years after Fauci met that patient, we may be well on the way to stopping AIDS, thanks to a new vaccine.

Photo from Mujahid Safodien/AFP/Getty Images.

Today, Fauci is the director of the National Institute of Allergy and Infectious Diseases (NIAID). They work to treat and prevent a wide range of diseases, including HIV/AIDS.

Thanks to the work of the NIAID and a whole host of other doctors, scientists, and organizations, our relationship to HIV/AIDS has completely changed since the early '80s. We can track its movements, prevent its spread, and use drugs to de-fang it once it's in the body.

But a vaccine — that holy grail of medicine — has remained elusive. So far, at least.

All that might change, though. A new HIV vaccine trial, known as HVTN 702, has just started, supported in part by Fauci and the NIAID. It's the most hopeful trial yet, based on an attempt from 2009 that lowered HIV infections rates by about 30%.

That first try was exciting, but it wasn't quite good enough to distribute, so Fauci and his team are hoping that this new trial could be the kicker.

For the site of the drug trial, the scientists chose South Africa, a nation that's been hit especially hard by HIV.

A Cape Town pharmacist checks documents on a fridge holding the vaccine. Photo by AP Photo/Schalk van Zuydam.

Fauci and the NIAID aren't the only ones working on this. Dr. Gita Ramjee is the director of South African Medical Research Council’s HIV Prevention Research Unit. She's been working on HIV prevention for years.

Ramjee explained that the location of the trial is significant. Worldwide, HIV/AIDS affects about 37 million people. 7 million of those cases are in South Africa. The country sees about 1,000 new infections every day, and women are especially at risk.

"In Southern Africa, the face of the epidemic is a woman's face," said Ramjee. That's partly due to biological factors, but also social ones. Women don't always have the power to negotiate condom use with their partner, for example, and there may be stigma around getting preventive care.

Ramjee is one of the scientists who has been trying hardest to help these women for years. She joined the vaccine push because she wanted to explore new ways to help people prevent infection and because she's seen the costs of HIV/AIDS far too many times.

"Seeing these women in person, seeing a 16- or 18-year-old already coming to the clinic HIV-positive, it's really, really heartbreaking," said Ramjee.

That's why it's encouraging to see just how big this trial is. South Africa's response recruited over 5,000 volunteers to take part.

One of the trial's 5,400 volunteers at an event in Soshanguve, South Africa. Photo from Mujahid Safodien/AFP/Getty Images.

As part of this latest trial, South Africa enrolled 5,400 sexually active men and women. Half will get the vaccine, half will get a placebo. All will be offered established HIV prevention methods.

The trials will test the efficacy of the vaccine, and they'll also test for any possible side effects. The first patient was enrolled on Oct. 26, 2016. Results are expected in late 2020.

Fauci and Ramjee aren't making any predictions just yet, but both noted how huge an even moderate win could be.

Photo from Mujahid Safodien/AFP/Getty Images.

"Having a vaccine, even if it's 50% efficacious, it's going to add to the toolbox that we have," said Ramjee.

Existing treatment and prevention methods such as condom use or vaginal rings have been able to take the edge off the infection rate, but they haven't been able to completely reverse the disease's trajectory. But immunization is a powerful tool, and added to our repertoire — well, that could be what finally tips the scales. It could be, as both Fauci and Ramjee said, the final nail in HIV's coffin.

Yes, this trial could fail, but even if it doesn't, it's heartening to talk to folks who will keep going until one does. Research is, after all, a learning process.

"Irrespective of what the results are — positive or negative or moderate — we're going to learn a lot," Ramjee said.

That's pretty cool. And on the cusp of this huge trial, it's also worth celebrating just how far we've come since the virus first appeared.

Fauci still sees HIV patients in the very same room where he first met that first patient more than 30 years ago. He said the advancements in HIV/AIDS care he's seen has been nothing short of breathtaking.

HIV/AIDS was once a death sentence. Today, with the right care, people can live long, happy, healthy, essentially normal lives. And we continue to see amazing strides in care, even now.

"It's been a tremendous, extraordinary evolution," he said.

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Fatherhood

Dad and daughter relationships perfectly  explained in 10 paintings

The bond between dads and daughters is amazing.

All illustrations are provided by Soosh and used with permission.

It's hard to truly describe the amazing bond between dads and their daughters.

Being a dad is an amazing job no matter the gender of the tiny humans we're raising. But there's something unique about the bond between fathers and daughters. Most dads know what it's like to struggle with braiding hair, but we also know that bonding time provides immense value to our daughters. In fact, studies have shown that women with actively involved fathers are more confident and more successful in school and business.

You know how a picture is worth a thousand words? I'll just let these images sum up the daddy-daughter bond.

A 37-year-old Ukrainian artist affectionately known as Soosh, recently created some ridiculously heartwarming illustrations of the bond between a dad and his daughter, and put them on her Instagram feed. Sadly, her father wasn't involved in her life when she was a kid. But she wants to be sure her 9-year-old son doesn't follow in those footsteps.

"Part of the education for my kiddo who I want to grow up to be a good man is to understand what it's like to be one," Soosh told Upworthy.

There are so many different ways that fathers demonstrate their love for their little girls, and Soosh pretty much nails all of them.

Get ready to run the full gamut of the feels.

1. Dads can do it all. Including hair.

parenting, dads, daughters, fathers, art, artworkA father does his daughter's hairAll illustrations are provided by Soosh and used with permission.

2. They also make pretty great game opponents.



parenting, dads, daughters, fathers, art, artwork, chessA father plays chess with his daughterAll illustrations are provided by Soosh and used with permission.

3. And the Hula-Hoop skills? Legendary.



parenting, dads, daughters, fathers, art, artwork, hula hoopA dad hula hoops with his daughterAll illustrations are provided by Soosh and used with permission.

4. Dads know there's always time for a tea party regardless of the mountain of work in front of them.



A dad talks to his daughter while working at his deskAll illustrations are provided by Soosh and used with permission.


5. And their puppeteer skills totally belong on Broadway.



A dad performs a puppet show for his daughterAll illustrations are provided by Soosh and used with permission.


6. Dads help us see the world from different views.



A dad walks with his daughter on his backAll illustrations are provided by Soosh and used with permission.


7. So much so that we never want them to leave.



a dad carries a suitcase that his daughter holds ontoAll illustrations are provided by Soosh and used with permission.


8. They can make us feel protected, valued, and loved.



A dad holds his sleeping daughterAll illustrations are provided by Soosh and used with permission.


9. Especially when there are monsters hiding in places they shouldn't.



A superhero dad looks over his daughterAll illustrations are provided by Soosh and used with permission.


10. Seeing the daddy-daughter bond as art perfectly shows how beautiful fatherhood can be.



A dad takes the small corner of the bed with his dauthterAll illustrations are provided by Soosh and used with permission.


This article originally appeared nine years ago.

fathers
Humor

Gen Zers hilariously try to explain to other generations what makes them laugh

"Half of Gen Z doesn't even get their own memes."

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Gen Z doesn't get their own humor.

When it comes to jokes, some generations love a very clear set-up-punch. "My wife is so lazy she… ba dum tss!"

For Gen Xers, "storytelling jokes" became more popular, made famous by the likes of Janeane Garofalo, Patton Oswalt, and David Cross. You were there for the hilarity peppered throughout a story, rather than the traditional short-form approach. Think Louis C.K., John Mulaney, or Kevin Hart.

- YouTubewww.youtube.com

But on the subreddit group r/outoftheloop, a blatant question was posed: "What is up with Gen Z humor?"

The question comes from a very earnest place. A 35-year-old Millennial woman simply wants to connect more with her 22-year-old Gen Z sister. The OP (@trainstationpoet) writes, "She is the best marshmallow squishy ray of light I’ve ever known. When I see her I just want to connect in every way possible to get that sibling good-good. She sends me some memes like this one and I genuinely do not understand ANY of them."

There is a link to Know Your Meme, which contains a picture of the following: a stick figure drawing of a smoking man with a hat entering through a door into a bunch of squiggles and capital "As." On top, it says "Are Ya Winning, Son? Don't forget to play The Last of Us too.." (I, too, am stumped.)

She then shares the same website with a piece entitled, "13 Reminders That Gen Z Kids Are Still The Future (Of Memes)" with different examples of what generations might find funny. Even the intro paragraph could be read as sarcastic, so wait—is THAT Gen Z humor?

For example, someone (and there doesn't seem to be a byline) writes, "There's nothing like a dose of good old generational stereotyping to distinguish between the different age groups. Boomers are the 'selfish and entitled ones' (depending on your age), whereas Millennials are the different, more self-aware brand of selfish and entitled (or self-loathing). As for Gen Z, they've got bigger fish to deep-fry than entering an argument about whether or not they're repeating the pattern."

They add, seemingly more sincerely, "The youngest generation is truly one of the strangest, because they laugh at their pain in a way that older generations haven't been able to. And there's something kind of endearing about that, in a messed-up sort of way. The cheerful pessimism and absurdist nature of Zoomer humor reminds us that even if everything won't be okay for the youth of today, at least they've gotten pretty good at making some truly detached and meaningless jokes online, as these examples remind us."

They then proceed to share memes to exemplify this premise. One, also sourced from Reddit, is titled "Le Gen Z has arrived." Underneath, it says "Boomer humor: Bad Wife, Millennial humor: Bad Life, Gen Z humor:" and it's merely a cartoon of a dog giving side-eye to a pink "beast version" of said dog who seems to be pawing a blue "beast version" of said dog and… oh never mind, I don't get it!

meme, side eye, gif, dog, gen z, humorSide Eye Dog Meme GIFGiphy

Back on the Reddit thread, the OP adds, "What I really don’t understand is the ‘why’ of the Gen Z humor. Boomer = low-hanging fruit that is 25% funny, 75% putting down other people. Millennial humor is self-deprecating jokes about wanting to be dead. Gen X humor is… idk, I never hear about them honestly. Then Gen Z humor (to me) is about taking acid, ending up on the astral plane and saying one to five words that vaguely represent the picture in the meme."

There are thousands of comments. One Redditor offers sound advice, which is essentially not to show fear. "Best advice to add: Don't say you don't get the meme. Half of Gen Z doesn't even get their own memes. You just sound old if you say that. The memes go fast and don't stick for long, so if you don't get it, don't ask about it."

Another explains that trends change so quickly for Zoomers, they want to make it seem like they're always keeping up. "When people hear ‘meme’ they expect a joke generally. I don’t think that’s how Gen Z sees it. Being in the know is the important part for them. I’m reminded of fashion trends… in my personal opinion, many fashion trends are ridiculous, memes are now fashion trends, it’s not about funny it’s about popular."

memes, gifs, confusing meme, gen z humor, generational humorMeme Reaction GIF by TokkingheadsGiphy

Many add that the jokes are deeply layered and purposely confusing. And when one starts to go down the rabbit hole, it actually is pretty brilliant in all its absurdity.

Bottom line, everything about Gen Z's humor is perfectly summed up by this comment: "Apparently postmodernism includes post-postmodernism."

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Joy

Adorable Golden Retriever absolutely loses it when he runs into his vet at a bar

No one has ever been this excited to see their doctor.

@cosmo_andtheoddparents/TikTok

He wuvs his vet.

Not every dog might jump with joy after seeing their vet out in public. But for Cosmo the Golden Retriever, it was practically Christmas all over again when he spotted his own vet, Dr. Jones, at a brewery.

In an adorable clip posted to TikTok, we see Cosmo in pure, unadulterated bliss as he snuggles with an equally happy Dr. Jones, who, considering he’s still in his scrubs, might have just gotten out of work to grab a quick pint.

Watch:

@cosmo_andtheoddparents When you run into your vet in public #goldenretrieversoftiktok #vetlife #animallovers #petparents #goldenretriever #goldenretrievers #doglife #dogmom #dailyfluff #charlestondogs #doglover #charlestondog #brewerydog ♬ original sound - Cosmo

Ugh, the cuteness is too much to handle! People in the comments could barely contain their secondhand joy.

“He looked over like, “Mom, do you see who this is?” one person wrote, while another said, “What in the Hallmark movie? Adorable!!”

One person even joked, “Did we all check the vet’s hand for a wedding ring? (Said as a married woman. Looking out for you all, or something.)”

According to Hannah Dweikat, Cosmo’s owner, the two actually share quite a history. She tells Upworthy that when Cosmo was but a wee pup, he “gave a scare” after eating a Sago Palm seed, which are highly toxic to dogs, from a plant in their backyard, which of course resulted in him being rushed to the animal hospital and staying there over the weekend.

While that’s every pet owner’s worst nightmare, and certainly a scary situation for the poor fur baby, Dweikat says that “the calm and patient demeanor” of Dr. Jones and his staff put Cosmo at ease. And because of this, “Cosmo has always loved going to see his friends—especially because they give him lots of treats and snuggles.”

Cosmo and Dr. Jones’ buddyship has also blossomed thanks to proximity, as Dweikat only lives down the street from the clinic. “Which means we get to see Dr. Jones and his staff out in public at times and Cosmo takes every chance he can get to say hi,” she explains. This time, however, she was able to capture it all on video. Yay for us!

What makes a good vet?

While not every vet, however gifted, will be able to elicit this type of reaction from their patients, having a calming presence like Dr. Jones is certainly a good sign for pet owners to be on the lookout for when shopping around for their own vet. But that’s not the only quality a good vet needs. According to Saint Matthews University, a vet also needs to have high stamina (both physically and mentally), as well as an ability to tolerate unpleasant situations (you can’t faint at the sight of blood or vomit), a high level of emotional intelligence (maybe all doctors should possess this skill, but especially those who work with animals), adaptability, a sense of enthusiasm, and finally, excellent communication skills.

Dr. Jones seems to have these attributes in spades, and his patients clearly love him for it. None so much as Cosmo, obviously.

By the way, if you’re in need of even more content featuring this precious pup, you can follow Cosmo on both TikTok and Instagram.

This article originally appeared in February

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Humor

JD Vance accidentally dropped the college football championship trophy and people have jokes

We can still come together to make fun of politicians.

CBS News/Youtube & Michael Li/Flickr

JD Vance "fumbles" the coveted college football national championship trophy.

It's a tradition for sports teams that win major championships to receive the honor of visiting the White House and meeting the President. The Super Bowl champion Philadelphia Eagles will be visiting soon. The World Series winning Los Angeles Dodgers visited earlier this year. And just this week, the national champions Ohio State Buckeyes took the stage with President Donald Trump and Vice President JD Vance, an Ohio State alum.

It was a simple photo opp. There would be no hard hitting questions from journalists about the economy or Russia. Everyone involved was there to simply celebrate the accomplishments of a talented and hard working group of young men in a controversy-free ceremony. What could possibly go wrong?

JD Vance had other plans. The moment he went to hoist the trophy, it appeared to quite literally fall apart in his hands.

Vance puzzled over the trophy for a moment as he tried to slide it toward himself. Then, as he began to lift it, the top half toppled over only to be caught by Ohio State running back TreVeyon Henderson before hitting the ground. You can actually hear the crowd gasping and holding their breath before Henderson saves it, all while the United States Marine Corps Band performs "We Are the Champions." You honestly couldn't script a more hilarious sequence if you hired Hollywood's funniest comedy writers.

To be fair, the college playoff national championship trophy is a little confusingly constructed. The bottom half is just a black stand for the trophy itself, which is the 26.5 inch tapered golden piece on top. So technically, Vance didn't break the trophy. He just didn't realize that it came apart in two pieces.

But it was too late. The blunder was caught by dozens and dozens of cameras, with the jokes about Vance "fumbling" the trophy nearly writing themselves.

Watch the wild video here:

- YouTubewww.youtube.com

Vance, the Internet's favorite punching bag as of late, suddenly found himself on the butt end of an avalanche of jokes.

Vance is no stranger to being made fun of on the Web. First, it was the theories that he wears eyeliner while simultaneously preaching about the death of masculinity. Then, it was enterprising social media users engaging in a war of one-upmanship to see who could create the most horrifying, bloated caricature of the VP.

And now, he can add this fumblerooski to his resume.

In a thread posted on the subreddit WatchPeopleDieInside, people came with their best jokes at Vance's expense:

"Ahh I see it's because the trophy didn't wear a suit and say thank you"

"That man has never held a trophy in his life."

"They are going to blame the Democrats for this."

On X, one user wrote, "JD Vance: Can't order donuts. Can't hold a normal conversation. Can't hold a trophy without breaking it."

Honestly, jokes were barely necessary. The photos are hilarious enough. The top half of the trophy tumbling limply into Vance's shoulder. Vance bending down, scrambling to pick up the base. It's all just *chefs kiss.*


People on the right had some fun at the VP's expense, too.

"Trophy must be made in China," one Reddit user joked.

"Dan Quail on steroids," added another.

Fox News couldn't help themselves, either. They made more than a few puns about Vance "fumbling" the trophy.

Even Vance himself had no choice but to try to take the mockery in stride.

The Trump administration is off to a controversial start, to put it extremely lightly. JD Vance's trophy snafu harkens back to a simpler time when we all came together to make fun of George W. Bush not knowing how to pronounce words or Gerald Ford tumbling down the stairs of Air Force One. There isn't much that's able to bring people from different sides of the aisle together anymore, and this one is just a minor blip in the grander scheme. But this little reprieve in the news cycle has definitely been a much needed source of comic relief.

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Kids

A daring boy invited classmates to his birthday party. One problem: there was no birthday party.

One mom knew the invite seemed fishy, but couldn't believe her eyes when they showed up.

Canva Photos

A mischievous boy created his own DIY birthday invitations.

We've all heard the sob stories about kids who invite the whole class to their birthday party, only for no one to show up. It's heartbreaking and horrific and all too common. But who's ever heard of a story where people showed up, but there was no birthday party?!

One mom is going viral for sharing a laugh-out-loud story of a young boy's ingenuity. It all started with an innocent-enough birthday invitation her own son brought home from school.

surprise, surprise party, birthday party, birthday, parenting, kidsWhen the parents don't even know about it, that's a successful surprise party.Giphy

The mom, who goes by Bree on TikTok, tells the tale in a now-viral clip. She says her son brought home a homemade (very homemade) birthday invitation from school. It read, in child's handwriting, "Your invited to my birthday, yay!" On the back, the chicken scratch read, "Come over and play soccer, play FIFA, do the trampoline..." and more.

Bree was suspicious of the invite from the get-go, but figured the boy's parents had just let him make his own. As an exhausted dad, I can definitely imagine a scenario where my wife and I just give up completely and let our youngest write whatever the heck she wants to and hand them out herself. So, although the handwritten invite was a little weird, it was easily explainable.

But then the strikes started adding up. Bree's son told her that they didn't have to RSVP and that the party was the very next day.

Bree, being a cool mom, decided to roll with it and show up anyway. And that's when things got hilarious.

“I turn the corner—not one balloon inside, not one table, not one chair inside, just [the boy's] dad and his three uncles. That's it. The dad looks at me, kind of surprised, and I was like, ‘Hi, we're here for the birthday party!’ And he just says, ‘Oh, okay, my wife's not home.’”

After waiting around for other people to show up to the party (unsuccessfully), Bree and her son noticed the boy taking a cake out of the fridge so everyone could dig in. At that point, Bree was pretty certain there was no party and they high-tailed it out of there.

Watch her tell the hysterical story here:


@breesquirrely

Talk about stressed 😂😂 #relatable #kids #mom #family #fypシ #trending

Viewers had a lot of theories and takes on the whole awkward debacle.

The video has been viewed almost 10 million times to date, with thousands reaching out in the comments to share their appreciation for the story. Some loved that Bree's son was such a good friend that he was willing to show up anywhere, anytime:

"At least you know your son is ready to rock for anyone. He doesn’t need decorations, cake, or even other guests ; that boy is ready to party."

"You're raising a good hearted young man. He didn't care for decor or anything he just wanted to show up for his friend."

@breesquirrely

Replying to @🌻 I highly doubt there was ever a birthday party 😂😂😂 ##update##part2##kids##relatable##fypシ##trending

Some said their own kids (or even themselves!) had pulled similar shenanigans in the past:

"My daughter did this, she made birthday invitations and passed them out to her classmates with my number noted. Had all the parents calling asking for address. There was no party."

"I'm 65 now...when I was in 1st grade I invited my entire class to come to my birthday party on Saturday. I woke up Saturday morning and told my Mom."

Others were concerned about the boy, wondering if he threw his own birthday party because no one else would. In replies to comments, Bree said that didn't seem to be the case. "I think it was a case of kids being kids and he forgot to tell his mama about the party he planned," she said.

Whatever the case, most commenters could agree that the boy in question wanted a play date with his friends and decided to take matters into his own hands to make it happen.

It's frustrating to be a kid and have so many things out of your control. When you're young, all your friendships are managed by your parents (for good reason) and while that keeps responsibility off your young shoulders, it's also challenging. Most of us remember being a kid and our best friend suddenly moving away with no warning! It's crushing and makes you feel helpless.

The boy who threw his own impromptu birthday party was practicing something called agency, which means the ability to make decisions about things that affect you and a belief that you have some power to control what happens to you. Agency is an important developmental milestone for kids and adults, and it's a key piece of our overall mental health. Some parents foster agency in their kids by printing up play date business cards that their children can hand out with a parent's phone number on them—seriously. The children may not arrange the play dates themselves but they can hand out cards to new friends they meet and have some control over their own social lives. Other parents encourage agency by asking their kids questions instead of telling them what to do, or practicing active listening techniques.

And then, of course, some kids take agency into their own hands with secret, hilarious plans that their parents know nothing about. If nothing else, this kid displayed an entrepreneurial spirit that will take him far one day.

For the parents out there, though, Bree warns to make sure birthday invitations are parent-approved before showing up anywhere. Unless you want to exercise your adventurous side, that is.

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