Impossible-sounding surgery cures blindness by implanting a patient's own tooth in their eye
"Tooth-in-eye" surgery sounds like something out of science fiction, but it permanently restores vision in 94% of patients.
You have to see it to believe it.
About 12 million people in the United States live with significant visual impairment. About a million of those people live with blindness. Unfortunately, there is no known cure for blindness. Therapies exist to slow vision loss, and some vision loss can be improved with treatment, but complete vision loss has proved to be a very tough nut for scientists to crack, in part because there are so many different potential causes of blindness.
Medical researchers have and continue to look into lots of diverse options, including stem cell therapies, gene therapies, bionic eyes, and now...teeth. Yes, you read that right. Teeth.
A 33-year-old man recently became the first person in Canada to have their sight restored by a rare and outrageous-sounding procedure: Osteo-odonto-keratoprosthesis, or OOKP.
OOKP has been around since the 1960s and has been performed around the globe, but is still relatively rare overall. Invented by Professor Benedetto Strampelli, the procedure is better known by its easy-to-remember, and fairly gross, nickname: "Tooth-in-eye surgery." Why in God's name is it called that? Buckle up if you're squeamish. Here's how it works:
Buckle up; this is going to be wild. Giphy
First, a tooth is removed from the patient. A small rectangular section of the tooth is shaved off and a hole is drilled in the middle of it. Imagine cutting a small circle out of the middle of a sheet of paper.
Then, a small plastic lens is inserted into the hole, almost like a window covering or a makeshift camera lens. The section of tooth acts like a frame to hold the new lens.
OK, now for the really wild part: The rectangular shaving of tooth, complete with plastic lens, is then embedded into the patient's cheek in order to grow new tissue and blood vessels. It will stay there for around two months while the new tissue develops.
The tooth is then removed from the cheek and surgically embedded into the patient's eyeball, effectively replacing the damaged cornea. The new eye is pink and bloodshot in appearance, and a little bulbous, with only a small block hole as an iris. But, miraculously, it works!
The patient's own teeth are used to prevent the body rejecting foreign tissue or materials. Tooth-in-eye surgery only works for vision loss caused by corneal damage, or damage to the surface of the eyes. It won't heal or replace the optic nerve or retina, so it's not a miracle cure for all forms of blindness. It also comes with some risks, but when it works, it works. One study showed that 94% of successful cases still had good eyesight almost 30 years later, with some formerly blind patients seeing well enough to drive cars.
The Canadian man became blind at the age of 13 after a terrible autoimmune reaction to ibuprofen. After dozens of surgeries and therapies, OOKP was his last-ditch effort to permanently restore his sight. Other treatments had helped but his sight would fade away over time. For now, his story is a massive success that doctors are hoping will inspire others to give the controversial procedure a try.
The video below shows the procedure and its aftermath:
@garcidltth1 #popularscience #knowledge #fyp #tiktok
We have to keep funding bizarre, off-the-beaten-path scientific research.
This sounds like one of those wacky things you'd see in the news and say, "Why are we spending millions of dollars trying to see if we can grow new eyeballs from teeth?!" But without critical and creative research like this, we'd be no further in treating conditions like blindness. A version of OOKP was performed successfully in the United States at The University of Miami in 2009.
Amazing medical breakthroughs can come from the strangest places. Fascinating discoveries have been made by making people drink their own blood and monitoring the effects, studying the chemical makeup of goose poop, and looking for answers in tree bark, snake venom, and rat poison.
Cheers to Professor Benedetto Strampelli, and his weird but effective stroke of inspiration.
Tommy Edison watches movies for a living. He's never actually seen one.
If you're only watching movies, you might be missing out.
Tommy Edison was born blind. That didn't stop him from falling in love with movies.
If your first reaction upon reading that was to wonder how a blind person watches movies, Edison understands. It's a question he's answered a lot in his job as the Blind Film Critic on YouTube.
"I'm always asked how I can enjoy films without being able to see them," he said. "But for me, there's so much more to the experience — there's story, there's dialogue, there's music and sound. It's a lot more than what you watch on the screen."
For blind movie lovers like Edison, knowing that there are actors and action on the big screen is only a small part of experiencing cinema.
Tommy Edison, the Blind Film Critic. Image via Tommy Edison, used with permission.
"For me, the biggest part of a film is the story," he said. "Movies like 'Goodfellas' or 'Clerks' don't even need the visuals — their storytelling is so strong and the performances are so skilled. As soon as those movies started, I was right in the story."
Even if a film doesn't have amazing performances, it can make up for it with an excellent soundscape. "There was an incredible movie called 'The Grey,' starring Liam Neeson, a few years back," said Edison. "Most of the action took place outside, and the sound editors took advantage of the surround sound in the theater to make it feel like we were right there with them. I could hear the rain all around me — so much that I wanted to wipe it off my head, it felt so real."
At the moment, a lot of big-budget movies revolve around action sequences without dialogue — a challenging situation for blind moviegoers. That's when audio descriptions are helpful.
A woman listens with headphone to a movie playing on her laptop. For blind movie watchers, hearing the action is just as good as seeing it. Image via iStock.
Like closed-captioning for the hearing-impaired, audio commentary helps vision-impaired or blind people follow along with TV and movie action during scenes with limited dialogue.
According to the American Council of the Blind, three American theater chains — AMC, Cinemark, and Regal — offer audio descriptions on all of their screens. Blind or vision-impaired moviegoers can go to the theater and wear a set of headphones that will play a narration track describing the film's key visual elements like costumes, sets, and other moments only sighted people would experience. Best of all, the track only runs during pauses in lines of spoken dialogue, ensuring non-sighted moviegoers don't miss anything.
For Edison, an audio description track changed his understanding of one of the most famous movies of the '90s. "I tried watching 'The Matrix' a few times without audio descriptions. I couldn't make it through more than about 20 or 30 minutes of it," said Edison. "The descriptions changed that; they helped me understand what it was about, and how cool of a film it was."
While Edison is appreciative of technological advancements like audio descriptions, he'd rather they weren't necessary.
If he had his way, Hollywood would simply get better at telling stories, rather than showing them.
This empty green-screen set could become an entire scene in a superhero popcorn flick. For blind moviegoers like Edison, that's a big problem. Image via iStock.
"The one genre that doesn’t really work for me as a blind audience member are the superhero movies," he said, conspiratorially. "'Thor,' 'X-Men,' 'Superman' — it all sort of seems to be eye candy. They have all these incredible performers, and they all know how to act — studios need to give them something to work with! At the very least, they need to talk to each other more during fight scenes, not just grunt and roar."
Movies and TV shows are part of our shared cultural fabric — whether we're watching them for the action on the screen or listening to them for the stories they tell.
While, as Edison said, "there's nobody audio-describing our lives," anyone can appreciate the moviegoing experience of blind people on their own. So next time you settle in for a night on the couch or head to the theater for a break (and some $12 popcorn), maybe try closing your eyes and listening to the film instead. You might end up seeing it in a whole new way.
Tommy Edison was born blind. That didn't stop him from falling in love with movies.
If your first reaction upon reading that was to wonder how a blind person watches movies, Edison understands. It's a question he's answered a lot in his job as the Blind Film Critic on YouTube.
"I'm always asked how I can enjoy films without being able to see them," he said. "But for me, there's so much more to the experience — there's story, there's dialogue, there's music and sound. It's a lot more than what you watch on the screen."
For blind movie lovers like Edison, knowing that there are actors and action on the big screen is only a small part of experiencing cinema.
Tommy Edison, the Blind Film Critic. Image via Tommy Edison, used with permission.
"For me, the biggest part of a film is the story," he said. "Movies like 'Goodfellas' or 'Clerks' don't even need the visuals — their storytelling is so strong and the performances are so skilled. As soon as those movies started, I was right in the story."
Even if a film doesn't have amazing performances, it can make up for it with an excellent soundscape. "There was an incredible movie called 'The Grey,' starring Liam Neeson, a few years back," said Edison. "Most of the action took place outside, and the sound editors took advantage of the surround sound in the theater to make it feel like we were right there with them. I could hear the rain all around me — so much that I wanted to wipe it off my head, it felt so real."
At the moment, a lot of big-budget movies revolve around action sequences without dialogue — a challenging situation for blind moviegoers. That's when audio descriptions are helpful.
A woman listens with headphone to a movie playing on her laptop. For blind movie watchers, hearing the action is just as good as seeing it. Image via iStock.
Like closed-captioning for the hearing-impaired, audio commentary helps vision-impaired or blind people follow along with TV and movie action during scenes with limited dialogue.
According to the American Council of the Blind, three American theater chains — AMC, Cinemark, and Regal — offer audio descriptions on all of their screens. Blind or vision-impaired moviegoers can go to the theater and wear a set of headphones that will play a narration track describing the film's key visual elements like costumes, sets, and other moments only sighted people would experience. Best of all, the track only runs during pauses in lines of spoken dialogue, ensuring non-sighted moviegoers don't miss anything.
For Edison, an audio description track changed his understanding of one of the most famous movies of the '90s. "I tried watching 'The Matrix' a few times without audio descriptions. I couldn't make it through more than about 20 or 30 minutes of it," said Edison. "The descriptions changed that; they helped me understand what it was about, and how cool of a film it was."
While Edison is appreciative of technological advancements like audio descriptions, he'd rather they weren't necessary.
If he had his way, Hollywood would simply get better at telling stories, rather than showing them.
This empty green-screen set could become an entire scene in a superhero popcorn flick. For blind moviegoers like Edison, that's a big problem. Image via iStock.
"The one genre that doesn’t really work for me as a blind audience member are the superhero movies," he said, conspiratorially. "'Thor,' 'X-Men,' 'Superman' — it all sort of seems to be eye candy. They have all these incredible performers, and they all know how to act — studios need to give them something to work with! At the very least, they need to talk to each other more during fight scenes, not just grunt and roar."
Movies and TV shows are part of our shared cultural fabric — whether we're watching them for the action on the screen or listening to them for the stories they tell.
While, as Edison said, "there's nobody audio-describing our lives," anyone can appreciate the moviegoing experience of blind people on their own. So next time you settle in for a night on the couch or head to the theater for a break (and some $12 popcorn), maybe try closing your eyes and listening to the film instead. You might end up seeing it in a whole new way.