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7 mindblowing medical breakthroughs that could occur in our lifetime

One day soon, you might be able to grow new teeth. Seriously.

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My family has a history of Parkinson's Disease, so I always see the headlines that promise some major scientific breakthrough in regards to the disease based on small, lab-based experiments or trials run on animals. They give us a glimmer of hope but, far too often, these treatments never see the light of day. The road from promising idea to having a real treatment available for patients is extremely long and arduous. Most potential new medications and therapies don't survive.

But... things do sometimes happen! There are massive medical breakthroughs being achieved all the time. Sometimes it's a new discovery, sometimes it's a successful clinical trial, and sometimes it's the fruit of all that labor finally becoming publicly available to people who need it the most. For example, an RSV vaccine just became available in 2023 for the first time. A powerful non-opioid pain killer was approved in 2024. A new drug came out to treat schizophrenia that was completely different than anything that had come before. Progress is being made every single year.

In our lifetime, say the next five to 20 years, we could see unbelievable advancements in treating certain medical conditions. Here are a few pretty amazing potential developments that are on the horizon.

Scientist working in a laboratory setting. Photo by Adam Bezer on Unsplash

1. Growing new teeth

Unlike sharks, humans are known to grow only two sets of teeth, our baby teeth and permanent adult teeth. If one gets knocked out or lost due to decay or infection, you're out of luck!

But researchers say growth buds exist in our gums for a third set, and scientists in Japan have had success in activating them to grow naturally. It could be a major gamechanger that could one day replace dentures and prosthetics. The team has moved onto human trials and has a target date of having a drug ready by 2030.

2. Cancer vaccines

Medical scientists have made amazing strides in cancer research, especially in the field of vaccines.

Did you know that lung cancer is considered to be the most deadly of the bunch? A lung cancer vaccine could be available very soon. If a cancer vaccine sounds odd, think of it this way: Cancer can be treated by chemotherapy and radiation, but there's always a chance of it coming back. People who have survived cancer could theoretically take the vaccine and massively improve their chances of reoccurrence.

A similar vaccine is showing promising results in clinical trials for pancreatic cancer.

3. Better treatment for Alzheimers

Alzheimer's Disease is one of the most destructive and heartbreaking conditions imaginable. It's also extremely difficult to treat, with most currently available therapies and medications focusing on slowing or temporarily relieving certain symptoms.

One new avenue scientists are exploring is a vaccine that could target a protein called tau, which clumps together and tangles up crucial neurofibers that deliver information in the brain. One such medication aims to activate a patient's immune system and produce "a strong antibody response against both pTau and its harmful aggregated form." The drug was recently fast-tracked by the FDA and has shown promising results in human clinical trials.

Another relatively new development is the availability of monoclonal antibody treatment, which helps slow the progression of the disease. Currently, the treatments are not particularly cost-effective but may become moreso in the near future.


smiling woman in gray cardigan Photo by Tatiana Zanon on Unsplash

4. Breakthrough treatment for Huntington's Disease

Huntington's is a fatal central nervous system disorder that shuts down key brain functions in patients like speech, walking, and cognitive function. Some of the symptoms can be treated but, so far, little can be done to slow or stop the progression of the disease.

However, a new drug known as PTC518 was recently fast-tracked by the FDA due to promising results in clinical trials. It attacks mutant Huntington protein in blood cells and in cerebrospinal fluid and has been shown to improve symptoms of the disease in a 12-month trial run. What's especially exciting is that this drug attacks the disease itself rather than just treating symptoms at the surface level.

5. Targeted viruses that kill antibiotic-resistant bacteria

Bacteria is getting smarter and evolving. Antimicrobial resistance is a grave threat to the global population as well-known antibiotics become less effective against infection and new antibiotics are expensive and difficult to develop.

(If you've ever dealt with a staph infection, you know how scary it is when drugs just... don't work.)

This is where special viruses, called bacteriophages or just phages, come into play. These viruses selectively target and kill bacteria, and were actually first used about 100 years ago. Scientist are coming around to using them again. In select settings, they've proven to be incredibly effective against resistant infections, but will need more testing before they become widely available. However, it's definitely possible that this become a viable alternative to antibiotics in some cases in the next few decades!

6. Synthetic and bioprinted organs


human heart Photo by camilo jimenez on Unsplash

There are simply not enough donor organs going around for all the people who need a healthy liver, heart, or kidney.

Luckily, incredible strides have been made in creating artificial organs that can function like the real thing. A man in Australia just lived for 100 days with a titanium heart while he awaited a transplant! And bioprinting technology – quite literally 3D printing using real tissue and living cells — has the potential to create new working organs from scratch in the near future. Genetically modifying animal organs to function in humans temporarily or maybe even permanently has also come an extremely long way and is a process that will drastically improve in the coming years.

7. A one-pill cure for Hepatitis B

Hepatitis B is a potentially fatal infection of the liver that affects hundreds of millions of people worldwide. There is a safe and effective vaccine available to some people, but it's only preventative and won't treat active infections.

A research team in Israel recently discovered that a low dose of well-known chemotherapy drug, Curaxin-137, completely destroyed a crucial and mysterious protein that the Hepatitis virus depends on. The testing was done in a lab setting, so the next step is clinical trials. The team hopes that one day in the not-so-distant future, patients could take a single dose and completely eradicate the virus in their system. That's about as close to a miracle-cure as you can get!

Not all of these potential breakthroughs will come to fruition, but it's pretty amazing to dig into the advancements and discoveries that are being made every day. This list is just scratching the surface, to say nothing of robotic surgeons that will make major surgeries less invasive, new treatments for baldness, nanotechnologies that can deliver medicine to specific parts of the body, and more. Ultimately, good news is coming relatively soon for people who need it.


My Dad suffered from Parkinson’s, a disease that methodically and steadily destroyed his body and mind  — and ultimately took his life.

During my dad's last remaining days in hospice care, ​my four siblings, mother, and I huddled around him and shared, amidst laughter and tears, stories about the man he was, the lessons he taught us through his own successes and failures, and the tremendous impact he had on those around him. Dad’s life was far from perfect, and he had had a rough last handful of years. Our time together helped all of us remember who Dad was when we was in his prime —  when he was our hero.

Dad, while nonverbal, was alert and attuned to what was happening around him. Occasionally one of us would look over and find a trace of a smile on his face, an observation we would point out to him and the others. Dad was clearly enjoying time with his entire family for the first time in over 20 years.


Throughout his closing days, Dad heard anecdote after anecdote about the legacy he was about to leave behind.

People shared the memories he would leave us with. Here are the lessons he left behind for me and my family:

1. Dream big.

Dad grew up in a small, middle-class Irish enclave in Queens, New York. His father would periodically take him to wealthy neighborhoods to walk around and show him what was possible for him when he got older. The message from his father was that this could all be his. To Dad, it was impossible to dream too big. He wanted the world for himself and his kids — and fully expected us all to get it. Dad pushed us to imagine the unachievable and race like hell to achieve it. When I told him I was going to write a business book, he told me to prepare for the New York Times Bestseller list.

2. Live big.

Dad packed his life with rich and full experiences at every turn. If Dad wanted to have something, he got it. If he wanted to do something, he did it. The moment he had two nickels to rub together, he spent them. Dad lived big.

“You only go around once,” was something Dad frequently said to justify a risky business play or explain away a lavish purchase. It seemed to serve as a reminder to him (and us) that life could be cut unexpectedly short and that it would be wise to get big experiences in while he (we) could.

3. Be present.

Dad spent most of our upbringing racing around the country consulting with and training business leaders. The moment he was done working, he would race back home just in time to coach a basketball game, have dinner with the family, or play a pickup game in the backyard. He wasn’t vacant or lost in his work when he was with us. When he was with us, he was fully with us.

Long after we went to bed, Dad would return to work, staying up until the wee hours of the morning to get a proposal out or prepare for the following day’s events. He threw himself into whatever he was doing and made you feel as if you were the center of his universe when you were with him. He was magnetic. Being present undoubtedly added to his magnetism.

4. Pick your moments. (But when they appear, pounce.)

Dad rarely made a move that didn’t have a purpose behind it. He had this remarkable skill of letting the insignificant things go and dealing head-on with the things that really mattered.

5. Be interested, not interesting.

In his final days, what struck us most was the overwhelming number of personal stories from old friends and extended family about the impact Dad had on their lives. Dad was fascinated by people, and he had an art for drawing out their stories. When Dad was at his best, he was comfortably and confidently Dad. And in that comfort and confidence, he could let go of his own ego and pull out the complexities of the people he was with, instead of sharing his own with others. His sincere interest in others drew them closer to him and left them convinced they were in the presence of someone endlessly interesting.

My siblings and I were with Dad when he passed. We were sad, of course.

But there was a positive feeling in the room as well — each of us left Dad that night feeling closer to him and each other than we had in a very long time. We left armed and more cognizant of the lessons he had equipped us with.

Sit down, close your eyes, and try to remember how you got to where you are.

How easy is it for you to visualize the path you took today? How did you remember where to go? Maybe you know to always turn at an important landmark — the tree your mom planted, for example. Maybe there was a sign telling you the right direction.


Photo from iStock.

For people living with dementia, these navigational clues can be hard to read.

According to the Alzheimer's Association, about 5 million Americans live with some form of dementia. Dementia isn't a single disease — rather, it's a broad category of cognitive and neurological symptoms. The most common cause of dementia is Alzheimer's disease, but there are many others, including strokes or Parkinson's disease.

Dementia can interfere with many of the brain's mental processes, including spatial memory — the part of the brain that deals with navigation. This is why many people living with dementia may sometimes find it hard to get around, even in familiar places.

Part of our ability to navigate lies in the hippocampus; dementia can interfere with processes in this region. Image from Henry Gray/Wikimedia Commons.

Getting lost can be especially dangerous for people who live with advanced forms of dementia — it can mean forgetting how to get home and being exposed to the cold or rain or running into dangerous situations like wandering across a highway.

A possible solution for this problem lies in the designs of the very buildings we live in.

Woodside Place is an assisted-living community in Pittsburgh, Pennsylvania, that was built by Presbyterian SeniorCare in 1991.


Photo by Presbyterian SeniorCare, used with permission.

Though not as common today, in the 1980s, many facilities used physical or chemical restraints to prevent their residents from moving around.

Woodside, on the other hand, was specifically built and decorated to accommodate the natural wandering tendencies of people living with dementia.

Clever design decisions — like the use of color — help reinforce and strengthen the residents' spatial memory.

Many care spaces are designed like hospitals, fairly sterile and visually repetitive, white hallway after white hallway. By making the space more colorful, Woodside provides a quick intuitive reminder for residents to identify where they are.


Photo by Presbyterian SeniorCare, used with permission.

At Woodside, even the staff's uniforms are color-coded based on which wing they work in.

"[Patients] may not remember my name, but they remember she's green, she belongs to me," Carrie Chiusano, executive director of Presbyterian SeniorCare's dementia care center, explained.

Staff uniforms are color-coded. Photo by Presbyterian SeniorCare, used with permission.

Another strategy Woodside uses is to have decorations and signs that are meaningful and packed with emotional relevance.

Outside Woodside's green treehouse-themed wing is a large tree decoration. These cueing devices are more than just props; they serve as subtle visual reminders and landmarks for residents.

Woodside has also invested in signs and decorations that have personal significance to the residents. For example, many residents have decorated their doors and living spaces with photographs of themselves, family, and friends, so that they can more easily identify which room is theirs.

This can apply to more than just personal pictures; it can apply to meaningful symbols as well. Mary O'Malley, a Ph.D. student at Bournemouth University in England, told Upworthy of a care facility she visited where one area was decorated with generic pictures of water lilies and another was decorated with a painting of the city's history.

Water lilies vs. New York City. Which means more to you? Images from iStock.

Though the lilies were very pretty, O'Malley said the residents' emotional connection with their home city ultimately seemed to be a more useful navigation tool.

Researchers like O'Malley are constantly looking for ways to design living spaces specifically for people living with dementia.

Along with her supervisors, O'Malley is studying how people learn and remember routes and directions. She's taking a multidisciplinary approach, using psychology, neuroscience, sociology, and perhaps most importantly, direct conversations and feedback from people living with dementia.

Mary O'Malley conducting research at Bournemouth University. Photo from Philip Hartley/Bournemouth University.

O'Malley is interested in what type of spatial memory is most susceptible to memory loss.

For instance, we know that most older adults seem to work better with landmarks ("head toward the church") rather than plain directions ("turn right at the church"). O'Malley wants to see if this pattern holds true in people living with dementia as well. She's also studying the way our brains read maps to see if maps can be more user-friendly.

As we learn more about these designs, we can incorporate them not just into care facilities and hospitals, but into community spaces too.

While care facilities can be designed for residents with specific needs, it's estimated that about 60% of people living with Alzheimer's live within the larger community, rather than in assisted-living facilities.

"If you want to support people so that they remain in the community, then you should be making these changes to the community," O'Malley said.

These design decisions, such as the use of visual reinforcement and meaningful decoration, could be easily incorporated into the spaces we see around us every day. Next time you find yourself stuck trying to navigate, think about all the little visual cues you take for granted and how easy it would be to make them better for everyone.

Researchers in Australia believe they've discovered something that could be a flying leap forward in the battle against Parkinson's disease:

Photo by Jens Maus/Wikimedia Commons.


The breakthrough? A way to detect the disease using a simple blood test.

Photo by PublicDomainPictures/Pixabay.

If they're right, this would be a big bleeping deal.

According to the Parkinson's Disease Foundation, currently there is no uniform method of testing for the condition. Prospective patients are observed by a neurologist for symptoms that indicate brain cell loss has already begun.

A blood test, like the one developed by the La Trobe University team, could detect the disease before symptoms show up, allowing patients to start treatment before they suffer too much irreversible damage.

How does the test work?

Photo by JPC24M/Flickr.

Science.

No, seriously. How does it work?

The research team discovered that Parkinson's causes cell mitochondria — which the faint, half-remembered voice of your ninth-grade biology teacher is currently reminding you is the "power plant of the cell" — to become hyperactive.

The test scans for byproducts of the abnormally behaving mitochondria.

As always, there's still lots more work to do.

Speaking to The Guardian, lead researcher Paul Fisher said his team didn't have the financial resources to study whether the hyperactive mitochondria detected by the test are entirely specific to Parkinson's or also occur in others with similar neurological conditions.

They've also run only one trial to date.

But it's the kind of discovery that provides a lot of hope to a lot of people.

Actor Michael J. Fox's foundation provided funding for the research that led to the discovery of the test. Photo by Astrid Stawiarz/Getty Images.

In addition to the estimated 500,000 to 1 million people with Parkinson's in the U.S. (about 60,000 new Parkinson's patients are diagnosed annually) and the 7 million to 10 million with it worldwide, there are also millions more people whose family history puts them at a greater risk to develop it.

Early detection might be the key to helping them live longer, healthier lives.

Actor and longtime anti-Parkinson's advocate Michael J. Fox's foundation provided funding for the research, once again proving that when you give money to science, science gives you back something awesome.

No flying cars yet.

GIF from "Back to the Future"/Universal.

But I'll take showing a debilitating disease who's boss any day of the week.