+
Health

New first-of-its-kind treatment for alopecia that triggers hair growth approved by FDA

The current treatment for alopecia is painful and long—this could change lives.

alopecia; hair loss

New treatment for alopecia.

Alopecia is something that affects people of all ethnicities, all over the world, and unfortunately effective treatment has been scarce. But there's potentially good news on the horizon for hair loss suffers. The FDA recently approved a drug called Olumiant, a systemic treatment for alopecia areata, the autoimmune disorder that causes hair loss. The drug works by interfering with the body’s confused messaging that tells it to attack hair follicles.


The world became instantly familiar with the word alopecia after the 2022 Oscars, where Will Smith infamously defended his wife, Jada Pinkett Smith, after Chris Rock made a joke about her baldness. Pinkett Smith has alopecia and decided to forego treatment and instead to simply shave her head. She talked about how painful the treatments are on a recent episode of Red Table Talk. On the episode, a dermatologist explained the localized treatment, which involves needle pricks directly into the scalp with a needle containing medication. The process is lengthy and painful, and requires frequent visits for these scalp jabs in an attempt to stave off further hair loss. It’s no wonder that many people decide to embrace balding and shave their head instead.

The newly approved drug has been on the market in the U.S. since 2018 as a treatment for rheumatoid arthritis, and while it does have several mild to moderate side effects, one of them, hair regrowth, is what drew attention to it as a treatment for alopecia areata. The best news is that it's taken orally, and doesn’t involve any tiny jabs in the scalp.

In the FDA's announcement, Dr. Kendall Marcus, director of the Division of Dermatology and Dentistry in the FDA’s Center for Drug Evaluation and Research, said, “Access to safe and effective treatment options is crucial for the significant number of Americans affected by severe alopecia. Today's approval will help fulfill a significant unmet need for patients with severe alopecia areata."

In the clinical trials, between 32% and 35% of patients who received the higher of two tested doses had enough hair to cover 80% of their scalp after 36 weeks (compared with between 3% and 5% of patients who received a placebo). This definitely shows promise, despite observed side effects such as respiratory infections, acne, high cholesterol, headaches, fatigue, urinary tract infections and more. If you’ve ever watched a commercial for a new medication, these side effects shouldn’t come as a surprise, nor should they derail the excitement of a medication that could boost so many people’s mental health.

To date, there hasn't really been an effective noninvasive treatment for alopecia areata and while the condition isn’t life threatening, the mental effects can be detrimental. On the episode of Red Table Talk, the mother of 12-year-old Rio Allred told of how her daughter died by suicide, which she believed was linked to the bullying she received due to her alopecia. Depression, anxiety and negative body image are all risks associated with having the hair loss condition, especially in women.

While this new treatment won't be effective on everyone and it comes with a daunting number of potential side effects, it certainly offers hope for many as an improvement over the standard "needle" treatment. Hopefully researchers will continue to make progress on treatments for alopecia that are readily available and safe.

Our home, from space.

Sixty-one years ago, Yuri Gagarin became the first human to make it into space and probably the first to experience what scientists now call the "overview effect." This change occurs when people see the world from far above and notice that it’s a place where “borders are invisible, where racial, religious and economic strife are nowhere to be seen.”

The overview effect makes man’s squabbles with one another seem incredibly petty and presents the planet as it truly is, one interconnected organism.

Keep ReadingShow less

Adrienne Bailon-Houghton talks about the reality of surrogacy.

No matter how you become a mother, the journey is worth it. But oftentimes people omit the negative parts for many reasons, whether it's a desire to not make people feel bad for them or to not appear ungrateful. Thankfully, the taboo around the hard topics of infertility and pregnancy have been lifting, and people are feeling more free to express themselves.

Recently, Adrienne Bailon-Houghton, former co-star of "The Cheetah Girls" and co-host of "The Real," revealed her own struggles with infertility and the mixed feelings that came along with it. While we know Bailon-Houghton eventually welcomed a son, Ever James, via surrogate, this is the first time we've heard the unexpected revelation of the new mom feeling frustrated by the surrogacy process.

During the time leading up to finding a surrogate, Bailon-Houghton and her husband, Isreal Houghton, tried to conceive for six years.

Keep ReadingShow less
@allbelongco/TikTok

How bizarre, how bizarre.

It should go without saying that it’s not cool to steal from your Airbnb. But that doesn’t mean it doesn’t still happen.

However, when one Airbnb host recently discovered a guest had—for some strange reason—stolen one of her paintings, then replaced it with a completely different painting, she decided to make the best out of a very uncool situation by sharing the story on TikTok.

As a result, viewers got to witness an continuously unraveling, truly bizarre modern-day art heist.

Okay, let’s get into it.

Keep ReadingShow less
Family

2023 Mother's Day gift guide helps you celebrate moms in style

If you’re looking for the perfect Mother's Day gifts for the incredible moms in your life, we've got you covered.

Editor's Note: Upworthy earns a percentage of revenue from items purchased on this list.


Mother's Day is just around the corner, and it's time to get shopping. And if you’re looking for the perfect Mother's Day gifts for the incredible moms in your life, we've got you covered! Our curated selection of thoughtful and unique presents will make any mom feel special and loved. From cozy pajama sets and smart mugs to personalized pet jewelry and heartfelt books, these gifts cater to a variety of interests and preferences. Our handpicked choices are the perfect way to express your gratitude and love.

Keep ReadingShow less
Health

Scientists have just discovered the ‘anxiety gene’ and what turns it off

This could completely change how we treat anxiety and depression.

A young woman struggles with anxiety.

Living with an anxiety disorder can feel like a constant battle against an invisible enemy. People with anxiety disorders feel constant, excessive worry, restlessness and irrational fears, often accompanied by physical symptoms such as rapid heartbeat, tightness in the chest and difficulty breathing.

These overwhelming feelings cast a shadow over daily life and make it difficult to focus or enjoy simple pleasures. Anxiety disorders can also feel isolating, as the sufferer may struggle to communicate their feelings, making it hard to receive support and understanding.

Anxiety disorders are among the most common forms of mental illness and studies show that an estimated 31.1% of U.S. adults experience an anxiety disorder at some time in their lives. Around half of all people who suffer from anxiety disorders go into remission at some point.

Keep ReadingShow less
@abbycashman7/TikTok

From worst day to best day in less than ten seconds

Sometimes the best cure for a bad day is a good surprise.

Just ask Abbie Cashman, a woman in Ireland whose entire day was completely turned around the minute she began feeding a pet crow from the window of her taxi. Cause why not?

In an interview with Today, Cashman shared that after discovering she had a flat tire while at work, the planets seemed to align so that getting home was impossible. No taxi would take her. The bus was full. Luck did not seem to be on her side.

Cashman made one last attempt to book a taxi through a rideshare app. Finally, someone was able to pick her up.

Little did she know that the taxi driver would not only get her home, but also introduce her to a special winged friend to lift her spirits.

Keep ReadingShow less