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Health

You're not going crazy. ADHD meds don't work while you're on your period

ADHD; period; ADHD medication

woman laying on bed

I was diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) Inattentive Type about three years ago—I was a fully functioning adult, married with children before finding out that my brain worked a bit differently. Of course I've known that I functioned a bit differently than my friends since childhood. The signs were there early on, but in the '80s diagnosing a girl with ADHD just wasn’t a thing that happened.

Much of the early criteria for ADHD was written based on how it presented in males, more specifically, white male children, and I was neither. Women like me are being diagnosed more and more lately and it’s likely because social media has connected us in a way that was lacking pre- doom scrolling days.

With the help of social media, women can connect with others who share the same symptoms that were once a source of shame. They can learn what testing to ask for and how to advocate for themselves while having an army of supporters that you’ve never met to encourage you along the way. A lot of women that are diagnosed later in life don’t want medication, they just want an answer. Finally having an answer is what nearly brought me to tears. I wasn’t lazy and forgetful because I didn’t care. I had a neurological disorder that severely impacted my ability to pay attention to detail and organize tasks from most important to least. Just having the answer was a game changer, but hearing that untreated ADHD can cause unchecked anxiety, which I had in spades, I decided to listen to my doctor and give medication a try.


About 30 minutes after my first pill I was actually able to sit still. My brain slowed down and thought one thing at a time. I was suddenly able to finish the tasks that I started in a few minutes instead of hours, or not getting done at all. I remember calling my older brother and crying into the phone telling him that for the first time in my life I was able to not only sit and create a list, but mark stuff off said list. The excitement over my new found executive functioning skills wrapped in a peach colored diamond shaped pill was short lived. For a week out of the month, the pill did nothing. My brain went back to ping ponging from idea to idea, subject to subject. Things for work went unfinished or were messily completed in a last minute hurry. It was beyond frustrating, and no one had an answer as to why my period affected my medication.

My psychiatrist at the time suggested that I was building up a tolerance, but I took “medication vacations” and really only took it during the work week. It wasn’t until I reached out in a group specifically for moms with ADHD out of sheer exasperation that I got answers. Comment after comment were women saying, “my meds don’t work when I’m on my period either.” So many women didn’t have an answer as to why, it was just something that they’ve accepted that comes along with being a woman with ADHD. A week out of the month, your medication that literally helps you function is essentially reduced to being a Tic-Tac. It has no effect, and the symptoms of ADHD are cranked up to 100 that week. It was the most fascinating, bizarre and infuriating revelation. Why isn’t this talked about more?

ADHD; ADHD medication

orange and white pills

Photo by Christina Victoria Craft on Unsplash

It seems that women are left to either struggle with thinking they’ve lost their minds or that their medication needs to be increased, when a lot of the time neither is true. In fact, after doing a bit of research I found a few articles written about the effects of estrogen on ADHD symptoms, but had difficulty finding one that was peer reviewed. Most articles were written by therapists and ADHD coaches that have been doing their own research into the matter to help their clients that menstruate.

One of the few peer reviewed articles found was by Chris Iliades, MD and peer reviewed by Lindsey Marcellin, MD, MPH. In the article, Iliades notes that “The hormone estrogen affects receptors in the brain that release the naturally occurring chemicals serotonin, dopamine, and norepinephrine. When estrogen levels drop during the weeks before a menstrual period or during the years before menopause, so does the level of these brain chemicals.” He goes on to explain, “because symptoms of ADHD are affected by many of these same brain chemicals, it stands to reason that women with ADHD are more sensitive to estrogen.”

The breakdown of how these chemicals work in conjunction with estrogen, which fluctuates throughout your menstrual cycle, is indeed interesting. But why are articles highlighting this issue outliers? Why aren’t doctors who prescribe these medications more forthcoming with this information? It makes you wonder if doctors are aware at all or if the biological makeup of women and girls taking ADHD medication is an afterthought that medicine has to catch up with. If it is an afterthought, there are thousands, if not hundreds of thousands of menstruating people who would love more research done on this—taking a weeks long vacation from work and daily life isn’t feasible. Here’s hoping for more research and doctors like Chris Iliades to tell us what to expect when ADHD and periods meet.

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Three women, three MS journeys: How multiple sclerosis looks different for everyone

Gina, Nathalie and Helga share their reactions to being diagnosed with MS and how they stay informed and positive in the face of ever-changing symptoms.

Courtesy of Sanofi

Helga, Nathalie and Gina all have MS, and their experiences show how differently the disease can manifest.

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It’s been 155 years since neurologist Jean-Martin Charcot gave the first lecture on a mysterious progressive illness he called “multiple sclerosis.” Since then, we’ve learned a lot. We know MS causes the immune system to attack healthy tissue, including damaging the brain and spinal cord. Resulting symptoms can be debilitating and include fatigue, blurred vision, memory problems and weakness. Huge advancements in our understanding of MS and its underlying causes, as well as treatment advances, have been made in the past few decades, but MS remains a complex and unpredictable reality for the 2.8 million+ people diagnosed around the world.

Ironically, the only real constant for people living with MS is change. There’s no set pattern or standard progression of the disease, so each person’s experience is unique. Some people with MS have mild symptoms that worsen slowly but sometimes improve, while others can have severe symptoms that drastically alter their daily lives.

All people with MS share some things in common, however, such as the need to stay informed on the ever-evolving research, find various lines of support and try to remain hopeful as they continue living with the disease.

To better understand what navigating life with MS really looks like, three women shared their MS stories with us. Their journeys demonstrate how MS can look different for different people and interestingly, how the language used to talk about the disease can greatly impact how people understand their realities.

woman with horse, woman riding horseGina loves riding her horse, Benita.Courtesy of Sanofi

Gina—Hamburg, Germany (diagnosed with relapsing multiple sclerosis in 2017)

When her youngest son was 4 months old, Gina started having problems with her eye. She’d soon learn she was experiencing optic neuritis—her first symptom of MS.

“Immediately after the diagnosis, I looked up facts on MS because I didn’t know anything about it,” Gina says. “And as soon as I knew what could really happen with this disease, I actually got scared.”

As her family’s primary income provider, she worried about how MS would impact her ability to work as a writer and editor. Her family was afraid she was going to end up in a wheelchair. However, for now, Gina’s MS is managed well enough that she still works full-time and is able to be active.

“When I tell somebody that I have MS, they often don't believe me the first time because I don't fulfill any stereotypes,” she says.

Overwhelmed by negative perspectives on living with MS, Gina sought support in the online MS community, which she found to be much more positive.

“I think it’s important to use as many positive words as you can when talking about MS.” It’s important to be realistic while also conveying hope, she says. “MS is an insidious disease that can cause many bad symptoms…that can be frightening, and you can't gloss over it, either.”

To give back to the online community that helped her so much, Gina started a blog to share her story and help others trying to learn about their diagnosis.

Though she deals with fatigue and cognitive dysfunction sometimes, Gina stays active swimming, biking, riding horses and playing with her sons, who are now 11 and 6.

Cognitive dysfunction is common in MS, with over half of people affected. It can impact memory, attention, planning, and word-finding. As with many aspects of MS, some people experience mild changes, while others face more challenges.

Gina says that while there’s still a lot of education about MS needed, she feels positive about the future of MS because there’s so much research being done.

woman in wheelchair holding medal, woman rowingNathalie is an award-winning rower with multiple international titles.Courtesy of Sanofi

Nathalie — Pennes Mirabeau, France (diagnosed with relapsing-remitting multiple sclerosis in 2002)

Nathalie was a teenager and a competitive athlete when she noticed her first symptoms of MS, but it would take four years of “limbo” before she was diagnosed.

“Ultimately, the diagnosis was more of a relief, than a shock,” she says. “Because when you have signs and you don’t know why, it’s worse than knowing, in the end, what you have.”

However, learning more about the disease—and the realities of disease progression—scared her.

“That glimpse of the future was direct and traumatic,” she says. Her neurologist explained that the disease evolves differently for everyone, and her situation might end up being serious or very mild. So, she decided to stop comparing herself to others with MS.

She said to herself, “We’ll see what happens, and you’ll manage it bit by bit.”

By 2005, Nathalie’s MS had progressed to the point of needing a wheelchair. However, that has not dampened her competitive spirit.

Nathalie began her international rowing career in 2009 and has won multiple world titles, including two Paralympic medals—silver in London and bronze in Tokyo. Now, at 42, she still trains 11 times a week. Fatigue can be a problem, and sometimes hard workouts leave her with muscle stiffness and shaking, but she credits her ongoing sports career for helping her feel in tune with her body’s signals.

“Over the years, I’ve learned to listen to my body, letting my body guide when I need to stop and take breaks,” she says.

Nathalie explains that she used to only look backwards because of the initial shock of her diagnosis. In time, she stopped thinking about what she couldn’t do anymore and focused on her future. She now lives in the following mindset: “Even when doors close, don’t miss out on those that open.” Instead of focusing on what she can’t do, she focuses on the opportunities she still has. Right now, this includes her training for the 2024 Paralympic Games in Paris, where she will compete for another rowing medal.

“I only go forward,” she says. “Well, I try, anyway…It’s easy to say, it’s not always easy to do. But that’s what I try to do.”

woman exiting water after swimming, woman with great daneHelga's Great Dane has become a helpful and beloved companion.Courtesy of Sanofi

Helga—Johannesburg, South Africa (diagnosed with relapsing multiple sclerosis in 2010)

When Helga first started having balance issues and numbness in her feet, she chalked it up to her training as a runner. But when the numbness moved to her face, she knew something was wrong. She never guessed it was MS.

“When I was diagnosed, I felt completely overwhelmed and clueless,” Helga says. “I felt that I had nowhere near enough information. I did not know anything about the disease…I had no idea that it was going to be a process of continually monitoring and adjusting your lifestyle.”

In the beginning, Helga’s symptoms developed slowly, and she didn’t appear ill to others. She was even able to run for a few years after her diagnosis, but she couldn’t do marathons anymore, and she began to fall frequently due to balance issues and right-foot dragging. Then her cognition issues became more problematic, especially in her job as a trainer in a printing company.

“My executive function, decision-making and short-term memory were affected to the point that I was eventually medically unfit for work,” she says. She stopped working in 2017.

However, she didn’t stop living life. Even though she could no longer run, she continued to swim competitively. She got a Great Dane puppy and trained him as a service dog to help her walk. She also serves as vice chair of the patient support organization Multiple Sclerosis South Africa, and she advises others who have been diagnosed to join a patient advocacy group as soon as possible to get reliable information and meet others with MS.

Helga says she is “hopeful” about the future of MS. “I must say that I am so grateful that we have all the new medications available, because my life would not be the same if it wasn't for that,” she adds.

Part of how she manages her MS is by looking at the positives.

“If I could tell the world one thing about MS, it would be that MS is an incurable disease of the nervous system, but it's also the greatest teacher of valuing your health, family, friends, and managing change in your life,” she says. “My life is diversified in a way that I never, ever thought it would, and MS has been honestly the greatest teacher.”

Each MS journey is unique – with each person impacted experiencing different struggles, successes, and feelings as they manage this unpredictable disease. But the common thread is clear – there is a critical need for information, support, and hope. We are proud to participate in World MS Day and share these incredible stories of living life while living with MS. To learn more about MS, go to https://www.sanofi.com/why-words-really-matter-when-it-comes-to-multiple-sclerosis.

MAT-GLB-2301642-v1.0-05/2023

This article was sponsored by Sanofi. Participants were compensated when applicable.

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via Pixabay

A sad-looking Labrador Retriever

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@zohtaco/TikTok

Zoe Gabriel, showing off her new purse from Charles & Keith

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