Actor Helen Mirren addressed graduates of Tulane University in a May 20, 2017, commencement speech peppered with candid one-liners and an adoration for New Orleans — a city she once called home.

"Why the hell are you graduating?" she quipped, professing her love for the Big Easy. "What possible reason is there to leave here and go find jobs?"

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Natasha Rossi believed she had the perfect life.

She had two awesome kids — two and a half-year-old identical twins — and the love and support of her boyfriend, Desi. Life, she thought, could only get better.

All photos via Upworthy/Walgreens.

Then, in January 2019, she was hit with some of the hardest news that anyone can hear.

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