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For the first time ever, a 13-year-old boy has been cured of a deadly brain cancer

The boy’s tumor disappeared after participating in a new clinical trial.

Boy who was cured of cancer posing with family for Christmas photos

Lucas Jemeljanova, then aged 5, with his parents and sister a year before he was diagnosed with DIPG. (via Facebook)

Lucas Jemeljanova poses with his family a year before being diagnosed with cancer (Facebook)

Few things strike fear in the heart of parents and doctors more than a cancer called diffuse intrinsic pontine glioma, or DIPG. Primarily found in children, DIPG is a highly aggressive brain tumor that is uniformly fatal, with less than 10 percent of children surviving longer than two years after diagnosis.

But for the first time ever, a 13-year-old boy from Belgium named Lucas Jemeljanova has beaten the odds. Diagnosed with DIPG at age six, Lucas’ doctor Jacques Grill told Lucas’ parents, Cedric and Olesja, that he was unlikely to live very long. Instead of giving up hope, Cedric and Olesja flew Lucas to France to participate in a clinical trial called BIOMEDE, which tested new potential drugs against DIPG.

Lucas was randomly assigned everolimus in the clinical trial, a chemotherapy drug that works by blocking a protein called mTOR. mTOR helps cancer cells divide and grow new blood vessels, while everolimus decreases blood supply to the tumor cells and stops cancer cells from reproducing. Everolimus, a tablet that’s taken once per day, has been approved in the UK and the US to treat cancers in the breast, kidneys, stomach, pancreas, and others—but until the BIOMEDE clinical trial, it had never before been used to treat DIPG.

Lucas Jemeljanova poses with his mother(lesja Jemeljanova / Facebook)

Though doctors weren’t sure how Lucas would react to the medication, it quickly became clear that the results were good.

“Over a series of MRI scans, I watched as the tumor completely disappeared,” Grill said in an interview. Even more remarkably, the tumor has not returned since. Lucas, who is now thirteen, is considered officially cured of DIPG.

Even after the tumor was gone, Grill, who is the head of the Brain Tumor Program in the Department of Child and Teenage Oncology at Gustave Roussy cancer research hospital in Paris, was reluctant to stop Lucas’ treatments. Until about a year and a half ago, Lucas was still taking everolimus once every day.

“I didn’t know when to stop, or how, because there was no other reference in the world,” Grill said.

While Lucas is the only one in the clinical trial whose tumor has completely disappeared, seven other children have been considered “long responders” to everolimus, meaning their tumors have not progressed for more than three years after starting treatment.

Lucas Jemeljanova poses with his mother to mark cancer awareness month Lucas Jemeljanova with his mother (Facebook)(lesja Jemeljanova / Facebook)

So why did everolimus work so well for Lucas? Doctors think that an extremely rare genetic mutation in Lucas’ tumor “made its cells far more sensitive to the drug,” Grill said, while the drug worked well in other children because of the “biological peculiarities” of their tumors.

While everolimus is by no means a cure, the trial has provided real hope for parents and families of children diagnosed with DIPG. Doctors must now work to better understand why Lucas’ tumor responded so well to the drug and how they can replicate those results in tumor “organoids”—artificially-grown cells that resemble an organ. After that, said Marie-Anne Debily, a researcher in the BIOMEDE trial, “the next step will be to find a drug that works as well on tumor cells.”

In the meantime, however, Lucas’ doctors are thrilled.

“Lucas’ case offers real hope,” said Debily.

Lucas Jemeljanova poses with his family Lucas Jemeljanova with his parents and sister(lesja Jemeljanova / Facebook)

This article originally appeared in June

From Your Site Articles

Visit Sweden

Popular

Sweden makes stunning decision to trademark its name to avoid confusion

The country is taking historic steps to fix the problem.

via Visit Sweden (used with permission)

A Swedish woman taking things into her own hands.

True

Sweden has existed for over 1,000 years, but travelers across the globe are confused because other places, inspired by the country’s untouched beauty and joyously inclusive culture, have taken its name.

Seven other places in the world call themselves Sweden, so to distinguish itself from the name-alikes, the Kingdom of Sweden is taking a bold, historic step that no country has before. It’s become the first to apply to trademark its name with the European Union Intellectual Property Office.

Visit Sweden likens the country’s problem to a luxury brand that has to contend with dupes, knockoffs, or bootlegs that fall short of the glory of the genuine article.

“It’s flattering that other places want to be called Sweden, but let’s be honest, there should only be one. Our Sweden. The one with the Northern Lights, endless forests, and the world’s best flat-pack furniture,” says Susanne Andersson, CEO at Visit Sweden.

- YouTubewww.youtube.com

By trademarking its name, Sweden will make things much less confusing for travelers worldwide. It’d be a shame for someone looking to visit Sweden’s majestic Lapland to mistakenly wind up in a place with no reindeer, Aurora Borealis, or cloudberries to be found.

The world-class research team at Visit Sweden knew it had to act when it realized that other destinations with the same name had tripped up travelers. People looking to vacation in Portland, Oregon, have accidentally wound up in Portland, Maine. Travelers yearning to experience the fall in Manchester, New Hampshire, have been deplaning in Manchester, England. “It happens more than you think!” the researchers admitted.

sweden, visit sweden, swedish vacation The Northern Lights in Sweden. via Visit Sweden, Photographer: Jann Lipka/imagebank.sweden.se

The E.U. Intellectual Property Office must act swiftly and allow Sweden to trademark its name so that travelers worldwide don’t miss the opportunity to experience an utterly unique country known for its serene landscapes, commitment to deep relaxation and personal freedom.

No one should ever miss out on staying on one of Sweden’s 267,570 islands, more than any other country. The Swedish archipelagos offer luxurious glamping, peaceful hikes, tranquil solitude and awe-inspiring, pristine nature.

sweden, visit sweden, swedish vacation A woman camping in the Swedish archipelago.via Visit Sweden, Photographer: Anders Klapp/imagebank.sweden.se

Sweden is a beautiful place to visit all year round, with bright summers, colorful falls, vibrant springs and dark, crisp winters. It is also a place to delight your tastebuds with a cuisine centered on healthy, locally sourced produce, with some preparation methods dating back to the Viking era.

The original Sweden is a place where one can relish Old World European history while also enjoying the modern pleasures of the most progressive countries in the world. Travelers can be whisked back into history by visiting the Naval Port of Karlskona, a well-preserved European naval town from 1680. Or, enjoy cutting-edge design, delicacies, art, music and culture in hip metropolitan destinations such as Stockholm or Sweden’s “coolest city,” Gothenburg.

Did we mention Sweden has an ABBA museum? Wait till the other 7 Swedens find out about that.

As you can see, Sweden is an incredibly unique destination that cannot be duplicated. It would be a tragedy for anyone intending to visit the original Sweden to mistakenly find themselves in a name-alike place that lacks its Scandinavian charm. You can do your part to stop the confusion by signing a petition to let Sweden trademark Sweden at Visit Sweden (the original).

sweden, visit sweden, swedish vacation A Swedish Midsommar celebration. via Visit Sweden, Photographer: Stefan Berg/Folio/imagebank.sweden.se

From Your Site Articles

Family

Woman who was pressured to quit her job to raise stepdaughter's baby makes a bold decision

This sparked an important conversation about family responsibility.

via Pixabay

When parents can't step up, should grandparents step in?

A story that recently went viral on Reddit’s AITA forum asks an important question: What is a parent’s role in taking care of their grandchildren? The story is even further complicated because the woman at the center of the controversy is a stepparent.

At the time of writing her post, the woman, 38, met her husband Sam, 47, ten years ago, when his daughter, Leah, 25, was 15. The couple married five years ago after Leah had moved out to go to college.

Leah’s mom passed away when she was 10.

When Leah became pregnant she wanted to keep the baby, but her boyfriend didn’t. After the disagreement, the boyfriend broke up with her. This forced Leah to move back home because she couldn’t afford to be a single parent and live alone on a teacher’s salary.

Leah’s story is familiar to many young mothers facing similar difficulties.

The father isn’t involved in the baby’s life as a caretaker or financially. Sadly, research shows that 33% of all children in the U.S. are born without their biological fathers living in the home.

Single motherhood comes with unique hardships.

via Alexander Grey/Unsplash

The new mother is a teacher and can’t afford to live on her own with a child. In 2019, a study found that out the top 50 U.S. cities, Pittsburgh is the only one where a new teacher could afford rent.

Today, Portland, OR has joined the very short list of cities where an "average teacher can afford 91.3% of apartments within community distance of their school" according to a recent study.

The stressors of taking care of the baby made Leah realize she needed help.

“But once she had the baby around 4 months back, Leah seemed to realize having a baby is not the sunshine and rainbows she thought it was,” the woman wrote on Reddit. “She barely got any sleep during the last four months. All the while Sam was helping her with the baby while I did almost all chores myself.”

“Now her leave is ending. She did not want to leave the baby at daycare or with a nanny,” the woman continued. “Sam and I both work as well.”

Leah asked her stepmother if she would stay home with the baby. The stepmother said no because she never wanted to have a baby and she has a job. “I asked why Leah can't stay home with the baby herself,” the woman wrote. “She said how she was young and had to build a career. I said many people take breaks to raise kids, and she broke down crying about how she was so tired all the time being a mom and needed something else in her life too.”

The demands of new motherhood are usually all-encompassing.

via Pixabay

After the woman told her stepdaughter no, her husband pressured her to stay home with the baby. But she refused to give up her job to raise her stepdaughter’s child. “Leah said yesterday how she wished her mom was alive since she would have had her back. She said I didn't love her, and my husband is also mad at me,” the woman wrote. The woman asked the Reddit community if she was in the wrong for “refusing to help my stepdaughter with the baby,” and the community responded with rapturous support.

"[The woman] should tell her husband to knock it off and stop trying to pressure her into raising his daughter’s baby. If he wants a family member to look after her baby while she works, then he can do it," user Heavy_Sand5228 wrote.

"This is Leah's baby that she alone chose to have. That doesn't obligate you to change YOUR life to suit her desires. The whole business of saying you don't love her because you won't quit your job to watch her baby is manipulative and messed up, and I'm shocked your husband is siding with her," user SupremeCourtJust-a** added.

Leah and many women like her are in this situation because, in many places, teachers are underpaid, rent is high, and not all dads pay child support, even those required by law.

Another commenter noted that the baby is much more the father’s responsibility than the stepmother's. "To add, Leah should consider seeking child support from her ex. Her kid should be getting that money," Obiterdicta wrote.

While there are resources to help stepparents connect with their stepchildren and step-grandchildren, it's important to remember that the responsibility to raise a child ultimately rests with the parent(s).

This article originally appeared last year.

From Your Site Articles

family

Science

The longest — and probably largest — proof of our current climate catastrophe ever caught on camera.

It was the largest such event ever filmed.

Exposure Labs

All GIFs and images via Exposure Labs.

Photographer James Balog and his crew were hanging out near a glacier when their camera captured something extraordinary. They were in Greenland, gathering footage from the time-lapse they'd positioned all around the Arctic Circle for the last several years.

They were also there to shoot scenes for a documentary. And while they were hoping to capture some cool moments on camera, no one expected a huge chunk of a glacier to snap clean off and slide into the ocean right in front of their eyes.

A glacier falls into the sea.

assets.rebelmouse.io

ocean swells, sea level, erosion, going green

Massive swells created by large chunks of glacier falling away.

assets.rebelmouse.io

It was the largest such event ever filmed.

For nearly an hour and 15 minutes, Balog and his crew stood by and watched as a piece of ice the size of lower Manhattan — but with ice-equivalent buildings that were two to three times taller than that — simply melted away.

geological catastrophe, earth, glacier melt

A representation demonstrating the massive size of ice that broke off into the sea.

assets.rebelmouse.io

As far as anyone knows, this was an unprecedented geological catastrophe and they caught the entire thing on tape. It won't be the last time something like this happens either.

But once upon a time, Balog was openly skeptical about that "global warming" thing.

Balog had a reputation since the early 1980s as a conservationist and environmental photographer. And for nearly 20 years, he'd scoffed at the climate change heralds shouting, "The sky is falling! The sky is falling!"

"I didn't think that humans were capable of changing the basic physics and chemistry of this entire, huge planet. It didn't seem probable, it didn't seem possible," he explained in the 2012 documentary film "Chasing Ice."

There was too much margin of error in the computer simulations, too many other pressing problems to address about our beautiful planet. As far as he was concerned, these melodramatic doomsayers were distracting from the real issues.

That was then.

The glacier ice continues to erode away.

assets.rebelmouse.io

In fact, it wasn't until 2005 that Balog became a believer.

He was sent on a photo expedition of the Arctic by National Geographic, and that first northern trip was more than enough to see the damage for himself.

"It was about actual tangible physical evidence that was preserved in the ice cores of Greenland and Antarctica," he said in a 2012 interview with ThinkProgress. "That was really the smoking gun showing how far outside normal, natural variation the world has become. And that's when I started to really get the message that this was something consequential and serious and needed to be dealt with."

Some of that evidence may have been the fact that more Arctic landmass has melted away in the last 20 years than the previous 10,000 years.

Watch the video of the event of the glacier calving below:

This article originally appeared nine years ago.

From Your Site Articles

For the first time ever, a 13-year-old boy has been cured of a deadly brain cancer

The boy’s tumor disappeared after participating in a new clinical trial.

The country is taking historic steps to fix the problem.

This sparked an important conversation about family responsibility.

Leah’s story is familiar to many young mothers facing similar difficulties.

It was the largest such event ever filmed.

It was the largest such event ever filmed.

But once upon a time, Balog was openly skeptical about that "global warming" thing.

In fact, it wasn't until 2005 that Balog became a believer.

Watch the video of the event of the glacier calving below:

They're funny because they're true.

Gordon shared 15 of his oh-so-real comics with us. They're all funny 'cause they're true.

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I love Gordon's comics so much because they're just about the reality of parenting — and they capture it perfectly.

"We love it. It's hard to find them."

Ariana Grande (2018)

Kate Beckinsale (2019)

Margaret Qualley (2019)

Kaia Gerber (2019-2020)

Phoebe Dynevor (2020)

Kim Kardashian (2021)

The best part? Anyone can do this to create a truly unique and meaningful Christmas gift.