+
upworthy
Health

A female scientist’s discovery may lead to the first 'on-demand' male birth control pill

“Men need an option so that the burden of contraception is not on females anymore,” says Dr. Melanie Balbach.

birth control, makle contraception, male pill

Close up of a man taking a pill.

Even though men have condoms and vasectomies, throughout history, the burden of contraception has ultimately been felt by women because they bear the ultimate responsibility if they become pregnant. To maintain their reproductive freedom, women must take hormone-altering pills, wear patches or insert hormone-filled rings into their vaginas.

They also deal with copper IUDs, shots and spermicide-soaked sponges.

Women also have to manage the cost and hassle of doctors' visits to get their contraception and are at the mercy of the state if they have an unwanted pregnancy. Isn’t it time more men stepped up and took responsibility for contraception?

The good news is that new medical development may provide hope for the countless women who are tired of the pills, IUDs and headaches that come with female contraceptives. The cool thing is that a woman is behind its discovery.


A new pill developed by Weill Cornell Medicine could become the first “on-demand” male oral contraceptive. The drug has been found to stop sperm “in their tracks” and prevents pregnancies in preclinical models.

The pill is fast-acting and can have a man ready for sex 30 to 60 minutes before intercourse. That’s about as long as it takes for Viagra to work its magic.

"Our inhibitor works within 30 minutes to an hour," Dr. Melanie Balbach, a postdoctoral associate in their lab, said in a statement. "Every other experimental hormonal or nonhormonal male contraceptive takes weeks to bring sperm count down or render them unable to fertilize eggs."

The inhibitor was discovered by Dr. Balbach accidentally while working on a treatment for an eye condition. Dr. Balbach found that when mice took a drug that inactivates soluble adenylyl cyclase (sAC), they produced sperm that could not propel themselves through the vaginal tract.

Research shows that men who cannot produce sAC due to genetic mutations are infertile.

After the drug takes hold, the sperm are rendered useless for about 24 hours and then return to normal. So, the drug is not only fast acting but rapidly reversible.

“What I like about the proposed contraceptive in this study is the on-demand option,” says Ulrike Schimpf at the KTH Royal Institute of Technology in Sweden. “It would act rapidly, temporarily, and is efficient at the first dose.”

The discovery could be a sea change in how males approach contraception. But some are rightfully afraid that men may lie about taking the pill in the heat of the moment.

After all these years that women have had to bear the burden of responsibility, there’s something poignant about the first potential male contraceptive pill being discovered by a woman.

“We need more [birth control] options, and men need an option so that the burden of contraception is not on females anymore,” Balbach told New Scientist. “We’re very optimistic that once men take the inhibitor, it will have the same effect.”

Dr. Balbach and Dr. Jochen Buck, a professor of pharmacology at Weill Cornell Medicine, are currently working to develop a new version of the drug that lasts longer before testing it on humans. They hope to go to clinical trials by 2025.

True

After over a thousand years of peaceful relations, European semi-superpowers Sweden and Switzerland may finally address a lingering issue between the two nations. But the problem isn’t either country’s fault. The point is that the rest of the world can’t tell them apart. They simply don’t know their kroppkakor (Swedish potato dumpling) from their birchermüesli (a Swiss breakfast dish).

This confusion on the European continent has played out in countless ways.

Swedish people who move to the United States often complain of being introduced as Swiss. The New York Stock Exchange has fallen victim to the confusion, and a French hockey team once greeted their Swiss opponents, SC Bern, by playing the Swedish National Anthem and raising the Swedish flag.

Skämtar du med mig? (“Are you kidding me?” in Swedish)

Keep ReadingShow less

Fowl Language by Brian Gordon


Brian Gordon is a cartoonist. He's also a dad, which means he's got plenty of inspiration for the parenting comics he creates for his website, Fowl Language (not all of which actually feature profanity).

He covers many topics, but it's his hilarious parenting comics that are resonating with parents everywhere.

"My comics are largely autobiographical," Gordon tells me. "I've got two kids who are 4 and 7, and often, what I'm writing happened as recently as that very same day."

Keep ReadingShow less
Photo by Hu Chen on Unsplash

Meeting a new sibling can go either way, but this big brother's reaction was the sweetest.

We've all seen our fair share of older-sibling-meets-new-baby videos, which are generally pretty darn adorable. But once in a while, one comes along that socks us square in the heart and has us desperately reaching for a tissue.

Brace yourselves, friends, because this is one video that truly requires a tissue warning.

Shared by @brianaarielle89 on TikTok, the video shows a preschooler dressed up in a dinosaur costume entering a hospital room to meet his newborn sibling for the first time. He asks, "Mommy, where is Hudson?" and is guided over to the cot where his baby brother is bundled.

At first, he walks right past him. But then he turns, sees him and simply stares for a few seconds.

Keep ReadingShow less
More

Ever wonder why people 100 years ago died so much younger? It's these 14 reasons.

1796. That's when we invented vaccines. An English doctor named Edward Jenner took incredible risks to try to rid his world of smallpox. Because of his efforts and the efforts of scientists like him, the only thing between deadly diseases like the ones below and extinction are people who refuse to vaccinate their kids. Don't be that parent.

FACT CHECK TIME! This article originally appeared on 11.21.14 and this infographic is based on data from 2012.

Unfortunately, because of the misinformation from the anti-vaccination movement, some of these diseases have trended up in a really bad way over the past several years.

Keep ReadingShow less
Joy

Owner of plus-size dress shop gifts $700 prom dress to 'shy' teen after watching her light up

Creating moments like these is why she opened her store in the first place.

@juicybodygoddess/TikTok

Elyse Monroe found the perfect dress, then found out it costs nothing.

Adolescence is a harrowing time for body image and self-esteem all around, but few milestones are as universally daunting as finding a prom dress. Whether it’s due to budget constraints, not being able to find a dress that fits, or both, what should be a fun event is often viscerally dreaded.

This was certainly the case for Summer Lucille. Lucille told Today.com that growing up, “if you weren’t skinny, there weren’t many options, and it was devastating for me because I’ve always loved fashion.”

She recalled, “I went to my prom looking like a church lady in a suit dress with a jacket because it was the only thing that fit. It was a very sad period in my life.”

Keep ReadingShow less

The fireman William Ziegler of New Orleans, Louisiana.

After you're gone, people will probably forget the exact things you said to them while you were alive, but they'll never forget how you made them feel.

Unfortunately, when people write obituaries that sum up a person's life they're often just a chronological list of factual details of their lives such as where they lived, where they worked, and how many children they had.

While those facts are important, they don't really explain the type of person the deceased was or how they made people feel. An obituary for fireman William Ziegler of New Orleans, Louisiana has attracted a lot of attention for how it hilariously summed up the life of a man who was a real raconteur.

Keep ReadingShow less


Asexuality is often misunderstood.

In general, it's believed to be the absence of any romantic interest, but asexual identity actually means that a person is not sexually attracted to anyone. Romantic feelings and the strength of those feelings can vary from person to person.

Currently, about 1% of adults have no interest in sex, though some experts believe that number could be higher. For a long time, information on asexuality was limited, but researchers recently have found information that gives us more knowledge about asexuality.

Being asexual can be tough, though — just ask the artists from Empathize This.

To demonstrate, they put together a comic on asexuality, defining it as a sexual orientation, not a dysfunction:

Keep ReadingShow less