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This woman's nose could be the key to spotting Parkinson's early.

"Milne realized she could, in essence, smell Parkinson's disease."

nose, smell, recognizing Parkinson, inspiration

Photo created from Pixabay

Smell could be a key identifier of Parkinson

This article originally appeared on 12.19.17

A woman's incredible nose might help scientists detect Parkinson's earlier than ever.

Joy Milne says she was living in Perth, Scotland, with her husband Les, when she noticed that he smelled different. Milne would later describe to the BBC as a kind of heavy, musky smell. The change was subtle, but it was there none-the-less. Milne says that at the time, she nagged Les a bit about missing showers, but didn't think much more of it.

Six years later, Les was diagnosed with Parkinson's disease, a neurodegenerative disease that attacks brain cells, causing tremors and other mobility issues. In the United States, about one million Americans live with the disease. There are therapies that can help with the symptoms, but no cure.

Her husband's diagnosis would inspire Milne to join the charity Parkinson's UK, where she was able to meet other Parkinson's patients. But something weird happened. The smell was back. And it wasn't unique to Les. She could detect it on other Parkinson's patients as well.

Milne realized she could, in essence, smell Parkinson's disease.

This is amazing, because there is currently no definitive early test for Parkinson's. The only way is to watch for symptoms, and by the time that happens, the disease has already started to impact the brain.

Milne got in touch with scientists to let them know what she was experiencing. Now, Milne's amazing nose might lead to a brand new early-detection test for the disease.

In the lab, she was able to identify Parkinson's patients in blind smell tests, even pegging on man who'd be diagnosed with the disease just a few months later. Using her nose, scientists have now identified 10 specific molecules that may be uniquely expressed in a Parkinson's patient's skin.

Milne's husband Les passed away in 2015, but researchers are hopeful that what they've learned from Milne's amazing nose could help other patients by catching the disease earlier than ever.

Science is powerful, but it sometimes takes paying attention to the small things in order to make big discoveries. As Perdita Barran, professor at Manchester University, told the Telegraph:

“It is very humbling as a mere measurement scientist to have this ability to help find some signature molecules to diagnose Parkinson's. It wouldn't have happened without Joy."

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MyHeritage is an online genealogy platform with 90 million family trees. Rossler's story hit close to home with Cappart.

"My husband lost his grandfather during the war. He died at the concentration camp in Auschwitz-Birkenau," Cappart told Newsweek. "My own great-grandmother also died in the camp at Ravensbrück. She was British and was in Belgium as part of the resistance. Sadly she was caught by the Nazis and deported. She never came back."

\u201cDavid Rossler, center, with members of the Bourlet family. A Belgian genealogist recently helped the 83-year-old man reunite with the family that saved him and his mother during World War II.\n\nhttps://t.co/CVWQ3SLbH0\u201d
— Stephen Uzzell (@Stephen Uzzell) 1653404305

“After browsing records and cross-referencing data, Cappart found an Anne-Marie Bourlet, born in Auderghem in 1929,” Lionel said, according to SWNS. “She discovered that Anne-Marie married someone with the surname Dedoncker and had five children—all of them possibly still alive.”

“After a bit more research, Cappart found Xavier, one of Georges Bourlet’s grandsons, and managed to contact him,” he continued.

Finally, after 75 years, David Rossler returned to the place where he hid in 1944 and 1945 and thanked Bourlet’s five grandchildren.

\u201cA man has returned to the home he and his mother hid in from the Nazis nearly 80 years ago - while his uncle and grandad died in Auschwitz. David Rossler, 85, was just five years old when he and his mother, Haja Sura Zoltak, were hidden by the Bourlet\n\nhttps://t.co/jmFZsupNaJ\u201d
— Times of Bristol (@Times of Bristol) 1675784891

“It was an incredibly emotional day for us,” Lionel explained. “I was able to see, with my own eyes, the place where my father was kept safe from the Germans all those years ago.”

“If I had Mr. Bourlet in front of me, I would want to kiss him,” said David. “To say thank you with all my body, with all my life, I am alive, I have a family of which I am very, very, very proud. To tell him that my life is thanks to him.”

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“Because of his heroic action, Georges was able to save the lives of my father and grandmother,” Lionel said. “Nine people were saved thanks to what he did; my brother, myself and our children would not be here today if not for his courage and kindness.”

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