+
Health

The first pill to treat postpartum depression may be ready this year and it could be a game changer

It's in final approvals with the FDA.

postpartum depression, postnatal depression, ppd treatment
via Freepik

A new mother struggling with postpartum depression.

We may be just months away from having the first-ever pill to help treat postpartum depression (PPD). The drug, called Zuranolone, was developed by Sage Therapeutics and Biogen, two companies out of Cambridge, Massachusetts. The FDA has given the drug’s application priority review and the period ends on August 5, 2023.

Currently, there is only one FDA-approved medication for PPD, Zulresso, which is only available through a 60-hour, one-time infusion and can cost up to $35,000 per treatment.

If the medication is approved, it can also be used to treat major depressive disorder (MDD).


What’s unique about the drug is that it is fast-acting. "We feel a tremendous responsibility to patients with MDD and PPD to deliver a potential new treatment option, which is so desperately needed. Most current approved therapies may take weeks or months to work. We are committed to advancing treatments that could help physicians and patients by addressing depression symptoms quickly," Dr. Laura Gault, chief medical officer at Sage Therapeutics Inc., said in a statement.

Zuranolone causes full remission of clinical depression within 45 days in 53% of women versus 30% who received the placebo, according to the study published in the Journal of the American Medical Association Psychiatry.

The new drug could be a godsend to the 500,000 women who suffer from PPD every year. In these women, what starts as a typical case of the “baby blues” can linger and become more intense and lead to an overwhelming loss of energy, irritability, inability to concentrate or make decisions and thoughts of harming themselves or their babies. It also severely inhibits their ability to care for their newborn child.

Symptoms of PPD can begin as early as during pregnancy and as late as a year after giving birth. In rare cases, it can develop into postpartum psychosis, an extreme mood disorder.

PPD is caused by the intense hormonal changes that happen within a woman’s body before and after giving birth. It can also result from numerous anxieties women feel after giving birth, such as the stress of being a “perfect mother,” the effect that pregnancy has on their bodies, being overtired and a lack of free time.

happy mom, happy baby, postpartum depression

A happy, healthy mother and child.

via Pexels.

Zuranolone could also provide faster relief for people dealing with MDD. In 2020, over 14 million Americans were diagnosed with MDD, which creates a persistent feeling of sadness and a loss of interest in things they used to enjoy. It can also affect their ability to have happy, healthy relationships.

In rare situations, MDD can lead to suicidal ideation. Studies show that MDD accounts for up to 89% of all suicides.

If Zuranolone is approved, it will give doctors another vital tool in improving people’s mental health that can relieve debilitating depression in less time. It will also help countless babies that need extra care in their early days from a loving and healthy mother.

If you or someone you know is having thoughts of suicide, call the Suicide and Crisis Lifeline at 988 for free, confidential support.

Our home, from space.

Sixty-one years ago, Yuri Gagarin became the first human to make it into space and probably the first to experience what scientists now call the "overview effect." This change occurs when people see the world from far above and notice that it’s a place where “borders are invisible, where racial, religious and economic strife are nowhere to be seen.”

The overview effect makes man’s squabbles with one another seem incredibly petty and presents the planet as it truly is, one interconnected organism.

Keep ReadingShow less

Florida deputy delivers baby on the side of the road

No mom dreams of delivering their baby on the side of the road. Visions of comfy birthing centers or a hospital room with the OBGYN that you've grown fond of are usually the images that come to mind. But not everyone has a delivery in their place of choice, and women that have birthed more than one child typically have faster labors.

People who have a lot of children often know their bodies and sense how quickly their babies might come, so they try to make it to the hospital before things get interesting. A couple in Florida who were expecting their sixth child attempted to head to the hospital before the baby arrived, but the baby had other plans.

Knowing he had to get his wife to the hospital quickly, Luis Lopez pulled over when he saw deputies on the side of the road and flagged them down for a police escort.

Keep ReadingShow less
@jfisher62/TikTok

"I had to unlearn it because it never was okay."

There is certainly no shortage of stories from women highlighting the glaring disparity between society’s expected responsibilities of husbands vs. wives. Some are a bit more lighthearted, poking fun at the absurdity. Others reflect utter frustration and had-it-up-to-here-edness with partners not doing their share of the work.

However, self-proclaimed “Clueless Husband” J Fisher’s honest, thoughtful retrospection on the subject shows that it’s not just female partners noticing that things need to change.

In a now-viral TikTok video, Fisher describes how he used to consider himself the “main character” of his relationship.

Keep ReadingShow less

Michelle Obama speaking during the Canadian State Visit to the White House.

When people become parents, the whole world suddenly revolves around a little bundle of joy that takes up all their time and energy. This makes it too easy for parents to let their personal aspirations, hobbies, and social lives slip away. Most of the time, it’s not a conscious choice but something that happens in the background while you’re busy caring for a child.

Then one day, you look up and wonder, where did my life go?

The big problem is that people can become so wrapped up in their identities as parents that when their children grow older and leave the house, they have no sense of self. Amy Morin, LCSW, says that this can lead to feelings of loss, loneliness, distress and conflicts with their partners.

Keep ReadingShow less
Heroes

Mom protects her young children from a swarm of bees as she's stung 75 times

She quickly picked her children up and got them to safety while risking herself.

Mom stung 75 times trying to protect her kids from bees

Bees are probably one of the most confusing insects right now because they're endangered, but also your instinct is to slap them away if they get too close. Bee stings hurt and their being on the endangered list doesn't make their stings any more pleasant. But with warm weather and flowers come bees ready to carry pollen on their furry bee legs and make delicious honey.

As long as they conduct their business away from people with exposed body parts, people tend to leave them alone. Again, being stung kinda sucks. Unfortunately, humans and bees cross paths fairly often, and for one mom in Arizona, that meant she and her children experienced a terrifying ordeal when running into a swarm.

The mom was trying to get pictures of her daughters in a field of flowers after Arizona had a "super bloom," when they were attacked by a swarm of bees.

Keep ReadingShow less

The “Chili’s (Welcome To Chili’s)" singers putting it down.

Few jingles get stuck in your head as easily as the Chili's "Baby Back Ribs" song, officially known as “Chili’s (Welcome To Chili’s),” which was first broadcast in 1996. The music starts with a deep-voiced man singing, “I want my baby back, baby back, baby back,” and builds from there to a sweet and tangy crescendo of “I want my baby back ribs!”

Guy Bommarito, the songwriter who wrote the jingle, says that Chilli’s execs weren’t initially too excited by his creation. "The response was, 'Yeah, that should work.' Nobody was blown away or overly impressed," he told Delish. "But it could've been my singing."

The song was later rerecorded in 1998 by a team of studio pros who took it to the next level with their soulful professionalism. The recording session video was shared on YouTube by singer Alvin Chea, and there’s something so satisfying and nostalgic about watching these guys put it down together at the same time.

In the new version, the iconic “baby back” bassline is sung by Alvin Chea, the bass singer for Grammy-winning gospel a cappella group Take 6, who also sang on Michael Jackson’s “This is It.” Dorian Holley, in the vest and tie, sang harmonies and also worked with the King of Pop as a background singer.

Oren Waters takes the lead on the “Chili’s” line and is part of the Waters family who sang background on MJ’s “Thriller" album. Louis Price sings the “barbeque sauce” line and was the lead singer of The Temptations from 1977 to 1980.