This group of Australian students has invented a new way to diagnose diseases — and it could lead to a tool that's better than what we've got now.
It's got the power to save lives, and in a few years you may even see it on a cellphone.
These dudes did it! And they're clearly pumped about it. Image courtesy of Dr. Lawrence Lee.
In 2014, the team of undergrads entered a prestigious biomolecular design competition at Harvard University from halfway around the world — and took home first place.
They call themselves Team EchiDNA. They're a group of Australian undergrads led by Dr. Lawrence Lee of the Victor Chang Cardiac Research Institute in Sydney.
So how did they win? They looked at nature.
Together with Lee, the team designed the Cooperative Molecular Biosensor that can detect viruses and diseases. They drew their inspiration from the design models found in nature.
"By copying nature, we're constructing new technologies that can potentially be used to drive a rapid diagnostic device," Lee explained to me via email.
Team members at the BIOMOD contest at Harvard's Wyss Institute. Image via Jacob Klensin/Wyss Institute.
The Cooperative Molecular Biosensor is a tiny sensor made up of a ring of beacons that light up when they bind to the target DNA — of a virus, pathogen, or even mutation.
Is the virus present? If yes, the ring lights up. That's all there is to it. You can see more of a scientific explanation in their project video.
But the bottom line: more sensitive testing and fewer false positives. Yes!
A computer model of the sensor. GIF via Team EchiDNA.
A group of students pulling this off is impressive. The short time frame they did it in is even more so.
The team was made up of undergraduates, and as Lee describes, had many other student responsibilities to worry about.
"We started the project quite late with only a few months for everything to come together," he says, explaining the challenges they've faced. "The team consisted of undergraduate students who still had to attend lectures, submit assignments, and sit exams."
Giving hope to procrastinators everywhere!
Winning the contest was just the beginning. This invention has the potential to revolutionize the way we diagnose diseases like Ebola.
At the same time the students were busy winning awards for their invention, Ebola was wreaking havoc on parts of the world. And flat-out scaring the rest of it.
Ebola virus. Image via Centers for Disease Control and Prevention.
During the outbreak, Lee says, "there was a clear need for definitive and rapid diagnostics of Ebola so that patients could be identified, isolated, and treated quickly to stem the spread of the disease."
Because the initial symptoms of Ebola are so similar to those of other diseases (malaria, typhoid fever, other bad stuff), diagnosis in the early stages can be very difficult. With current technology, a patient may be in the hospital for multiple days before a positive Ebola diagnosis is made.
Team EchiDNA saw the need to rapidly diagnose Ebola and tailored their design to help fill that void.
The team created their design to target the DNA of the Ebola virus — although, as Lee explains, "I must stress that the capacity to detect Ebola DNA sequences in laboratory setting is a long way from robust and accurate diagnostics in patient samples."
The team presenting their project at the BIOMOD contest. Image via Jacob Klensin/Wyss Institute.
In other words — the device is a long way from being sent into the field. But they are working to get there.
And once the design is perfected, it can be tailored to diagnose a wide range of other specific diseases: tuberculosis, HIV, or even a common flu.
So what's next? Lee said he and his lab (which still includes a couple members of the winning team) are working to refine the sensor and make it "so sophisticated you can test for bacteria or viruses by plugging a blood sample into your mobile phone," according to their press release.
Can you imagine!? A cell phone that diagnoses disease. Whoa. Image via Thinkstock.
These students should be so proud — and we should be so thankful for the young brains around the world helping to transform the future.
The technology being developed could drastically change the course of an Ebola outbreak — and other diseases — and stop it in its tracks before it can get out of hand. Life-saving!



A Generation Jones teenager poses in her room.Image via Wikmedia Commons
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An Irish woman went to the doctor for a routine eye exam. She left with bright neon green eyes.
It's not easy seeing green.
Did she get superpowers?
Going to the eye doctor can be a hassle and a pain. It's not just the routine issues and inconveniences that come along when making a doctor appointment, but sometimes the various devices being used to check your eyes' health feel invasive and uncomfortable. But at least at the end of the appointment, most of us don't look like we're turning into The Incredible Hulk. That wasn't the case for one Irish woman.
Photographer Margerita B. Wargola was just going in for a routine eye exam at the hospital but ended up leaving with her eyes a shocking, bright neon green.
At the doctor's office, the nurse practitioner was prepping Wargola for a test with a machine that Wargola had experienced before. Before the test started, Wargola presumed the nurse had dropped some saline into her eyes, as they were feeling dry. After she blinked, everything went yellow.
Wargola and the nurse initially panicked. Neither knew what was going on as Wargola suddenly had yellow vision and radioactive-looking green eyes. After the initial shock, both realized the issue: the nurse forgot to ask Wargola to remove her contact lenses before putting contrast drops in her eyes for the exam. Wargola and the nurse quickly removed the lenses from her eyes and washed them thoroughly with saline. Fortunately, Wargola's eyes were unharmed. Unfortunately, her contacts were permanently stained and she didn't bring a spare pair.
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Since she has poor vision, Wargola was forced to drive herself home after the eye exam wearing the neon-green contact lenses that make her look like a member of the Green Lantern Corps. She couldn't help but laugh at her predicament and recorded a video explaining it all on social media. Since then, her video has sparked a couple Reddit threads and collected a bunch of comments on Instagram:
“But the REAL question is: do you now have X-Ray vision?”
“You can just say you're a superhero.”
“I would make a few stops on the way home just to freak some people out!”
“I would have lived it up! Grab a coffee, do grocery shopping, walk around a shopping center.”
“This one would pair well with that girl who ate something with turmeric with her invisalign on and walked around Paris smiling at people with seemingly BRIGHT YELLOW TEETH.”
“I would save those for fancy special occasions! WOW!”
“Every time I'd stop I'd turn slowly and stare at the person in the car next to me.”
“Keep them. Tell people what to do. They’ll do your bidding.”
In a follow-up Instagram video, Wargola showed her followers that she was safe at home with normal eyes, showing that the damaged contact lenses were so stained that they turned the saline solution in her contacts case into a bright Gatorade yellow. She wasn't mad at the nurse and, in fact, plans on keeping the lenses to wear on St. Patrick's Day or some other special occasion.
While no harm was done and a good laugh was had, it's still best for doctors, nurses, and patients alike to double-check and ask or tell if contact lenses are being worn before each eye test. If not, there might be more than ultra-green eyes to worry about.