This group of Australian students has invented a new way to diagnose diseases — and it could lead to a tool that's better than what we've got now.
It's got the power to save lives, and in a few years you may even see it on a cellphone.
These dudes did it! And they're clearly pumped about it. Image courtesy of Dr. Lawrence Lee.
In 2014, the team of undergrads entered a prestigious biomolecular design competition at Harvard University from halfway around the world — and took home first place.
They call themselves Team EchiDNA. They're a group of Australian undergrads led by Dr. Lawrence Lee of the Victor Chang Cardiac Research Institute in Sydney.
So how did they win? They looked at nature.
Together with Lee, the team designed the Cooperative Molecular Biosensor that can detect viruses and diseases. They drew their inspiration from the design models found in nature.
"By copying nature, we're constructing new technologies that can potentially be used to drive a rapid diagnostic device," Lee explained to me via email.
Team members at the BIOMOD contest at Harvard's Wyss Institute. Image via Jacob Klensin/Wyss Institute.
The Cooperative Molecular Biosensor is a tiny sensor made up of a ring of beacons that light up when they bind to the target DNA — of a virus, pathogen, or even mutation.
Is the virus present? If yes, the ring lights up. That's all there is to it. You can see more of a scientific explanation in their project video.
But the bottom line: more sensitive testing and fewer false positives. Yes!
A computer model of the sensor. GIF via Team EchiDNA.
A group of students pulling this off is impressive. The short time frame they did it in is even more so.
The team was made up of undergraduates, and as Lee describes, had many other student responsibilities to worry about.
"We started the project quite late with only a few months for everything to come together," he says, explaining the challenges they've faced. "The team consisted of undergraduate students who still had to attend lectures, submit assignments, and sit exams."
Giving hope to procrastinators everywhere!
Winning the contest was just the beginning. This invention has the potential to revolutionize the way we diagnose diseases like Ebola.
At the same time the students were busy winning awards for their invention, Ebola was wreaking havoc on parts of the world. And flat-out scaring the rest of it.
Ebola virus. Image via Centers for Disease Control and Prevention.
During the outbreak, Lee says, "there was a clear need for definitive and rapid diagnostics of Ebola so that patients could be identified, isolated, and treated quickly to stem the spread of the disease."
Because the initial symptoms of Ebola are so similar to those of other diseases (malaria, typhoid fever, other bad stuff), diagnosis in the early stages can be very difficult. With current technology, a patient may be in the hospital for multiple days before a positive Ebola diagnosis is made.
Team EchiDNA saw the need to rapidly diagnose Ebola and tailored their design to help fill that void.
The team created their design to target the DNA of the Ebola virus — although, as Lee explains, "I must stress that the capacity to detect Ebola DNA sequences in laboratory setting is a long way from robust and accurate diagnostics in patient samples."
The team presenting their project at the BIOMOD contest. Image via Jacob Klensin/Wyss Institute.
In other words — the device is a long way from being sent into the field. But they are working to get there.
And once the design is perfected, it can be tailored to diagnose a wide range of other specific diseases: tuberculosis, HIV, or even a common flu.
So what's next? Lee said he and his lab (which still includes a couple members of the winning team) are working to refine the sensor and make it "so sophisticated you can test for bacteria or viruses by plugging a blood sample into your mobile phone," according to their press release.
Can you imagine!? A cell phone that diagnoses disease. Whoa. Image via Thinkstock.
These students should be so proud — and we should be so thankful for the young brains around the world helping to transform the future.
The technology being developed could drastically change the course of an Ebola outbreak — and other diseases — and stop it in its tracks before it can get out of hand. Life-saving!



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Communications expert shares the perfect way to gracefully shut down rude comments
Taking the high ground never felt so good.
A woman is insulted at her job.
It came out of nowhere. A coworker made a rude comment that caught you off guard. The hair on the back of your neck stands up, and you want to put them in their place, but you have to stay tactful because you're in a professional setting. Plus, you don't want to stoop to their level.
In situations like these, it helps to have a comeback ready so you can stand up for yourself while making making sure they don't disrespect you again.
Vince Xu, who goes by Lawyer Vince on TikTok, is a personal injury attorney based in Torrance, California, where he shares the communication tips he's learned with his followers. Xu says there are three questions you can ask someone who is being rude that will put them in their place and give you the high ground:
Question 1: "Sorry, can you say that again?"
"This will either make them have to awkwardly say the disrespectful remark one more time, or it'll actually help them clarify what they said and retract their statement," Xu shares.
Question 2: "Did you mean that to be hurtful?"
The next step is to determine if they will repeat the disrespectful comment. "This calls out their disrespect and allows you to learn whether they're trying to be disrespectful or if there's a misunderstanding," Xu continues.
Question 3: "Are you okay?"
"What this does, is actually put you on higher ground, and it's showing empathy for the other person," Xu adds. "It's showing that you care about them genuinely, and this is gonna diffuse any type of disrespect or negative energy coming from them."
The interesting thing about Xu's three-step strategy is that by gracefully handling the situation, it puts you in a better position than before the insult. The rude coworker is likely to feel diminished after owning up to what they said, and you get to show them confidence and strength, as well as empathy. This will go a lot further than insulting them back and making the situation even worse.
Xu's technique is similar to that of Amy Gallo, a Harvard University communications expert. She says that you should call out what they just said, but make sure it comes out of their mouth. "You might even ask the person to simply repeat what they said, which may prompt them to think through what they meant and how their words might sound to others," she writes in the Harvard Business Review.
More of Gallo's suggested comebacks:
“Did I hear you correctly? I think you said…”
“What was your intention when you said…?”
“What specifically did you mean by that? I'm not sure I understood.”
“Could you say more about what you mean by that?”
Ultimately, Xu and Gallo's advice is invaluable because it allows you to overcome a negative comment without stooping to the other person's level. Instead, it elevates you above them without having to resort to name-calling or admitting they got on your nerves. That's the mark of someone confident and composed, even when others are trying to take them down.