+
upworthy
More

Meet the man behind a new HIV vaccine that could help end the virus for good.

Dr. Robert Gallo has spent decades aiming to end AIDS.

If there ever were a pioneer in the war on AIDS, Dr. Robert Gallo would certainly fit the bill.


Photo by Win McNamee/Getty Images.


He was among the leading researchers who discovered HIV actually causes AIDS back in 1984.

Photo by Jim Watson/AFP/Getty Images.

That may seem like common knowledge today. But back in the 1980s — when the AIDS crisis was ravaging communities across the U.S. and very little was known about the virus — it was nothing short of groundbreaking.

He then spearheaded a blood test that can detect the virus in humans.

Photo by Win McNamee/Getty Images.

The blood test has had big ramifications in curbing HIV infections, as health care workers became equipped to rapidly diagnose infected patients.

And on Oct. 8, 2015, Gallo was at it again, announcing yet another big step in the fight against HIV: His potentially game-changing vaccine is going to human trial.

Photo by Jim Watson/AFP/Getty Images.

Sure, there are other HIV-fighting vaccines in human trial (about 30, in fact). But Gallo's vaccine, which has taken his team at the University of Maryland's Institute of Human Virology nearly two decades to produce, stands out ... in a good way.

There are many strains of HIV that can affect the immune system. And that makes creating a universal vaccine that stops all of them a bit tricky. If proven successful, however, Gallo's vaccine would protect patients' immune systems from the variations of the virus classified under "HIV-1," which constitutes the vast majority of infections worldwide.

"Our HIV/AIDS vaccine candidate is designed to bind to the virus at the moment of infection, when many different strains of HIV found around the world can be neutralized. We believe this mechanism is a major prerequisite for an effective HIV preventive vaccine." — Dr. Gallo

Enrollment in the trial opened this month, and the institute is looking for 60 people to participate in its year-long phase 1, according to The Baltimore Sun.

It's a promising step forward in the fight against a virus that's had a massive impact on global health.

There are about 35 million people living with HIV/AIDS around the world, according to the World Health Organization. About 1.5 million people died from the virus in 2013 alone. Sub-Saharan Africa — where nearly 71% of people living with HIV globally reside — has been affected far more than other regions of the world.

An HIV-positive mother holds her baby in Malawi. Photo by Marco Longari/AFP/Getty Images.

Although new medicines have helped HIV patients live longer, healthier lives, there is still no cure for the virus. And even for those fortunate enough to be living in regions with access to such medicines, drugs can be expensive (although that doesn't stop some greedy pharmaceutical company CEOs from inflating prices even further ... yeah, I'm talking about you, Martin Shkreli).

Gallo's vaccine could be huge. But even if it turns out to be, there are plenty of hurdles before patients can benefit.

Gallo's announcement is exciting! But let's not put the cart before the horse. Before the vaccine gets clearance from the FDA and becomes a welcomed reality for patients, it has to successfully pass a range of human trials. And that will take several years to complete.

Photo by Jim Watson/AFP/Getty Images.

But Gallo is confident the long road ahead will bring promising results.

"Can I promise absolute success? No," Gallo said of the vaccine's potential, according to The Baltimore Sun. "Do I hope it leads to a series of advances in the fields? Yes. And I think it will lead to some advances."

A pitbull stares at the window, looking for the mailman.


Dogs are naturally driven by a sense of purpose and a need for belonging, which are all part of their instinctual pack behavior. When a dog has a job to do, it taps into its needs for structure, purpose, and the feeling of contributing to its pack, which in a domestic setting translates to its human family.

But let’s be honest: In a traditional domestic setting, dogs have fewer chores they can do as they would on a farm or as part of a rescue unit. A doggy mom in Vancouver Island, Canada had fun with her dog’s purposeful uselessness by sharing the 5 “chores” her pitbull-Lab mix does around the house.

Keep ReadingShow less
Joy

5-star Scottish resort offers whimsical afternoon tea experience with 'naughty sheep'

Cameron House's Woolly Wellness retreat includes tea in the garden with adorably rude guests.

Cameron House/Naughty Sheep

Cameron House's Woolly Wellness retreat includes a unique sheep encounter.

Remember when "goat yoga" was all the rage? And then "cow cuddling" and "turkey cuddling" made everyone's bucket lists?

Now we can add "nuzzling with naughty sheep" to the mix, but with a fancy Scottish twist.

Less than an hour from Glasgow, Scotland, the Cameron House resort sits on the bonnie banks of Loch Lomond, looking as if it were plucked straight out of a fairy tale. Sprawling green grounds, gorgeous lake views and a four-story castled mansion greet guests as their "home away from home" (only better), and a perusal of the reviews show guests raving about the 5-star resort's elegance, beauty and exceptional service.

I mean, just look at this place:

drone view of cameron house grounds and lakeCameron House sit on Lake Lochmond in Scotland.Cameron House


Keep ReadingShow less
Innovation

A student accidentally created a rechargeable battery that could last 400 years

"This thing has been cycling 10,000 cycles and it’s still going." ⚡️⚡️

There's an old saying that luck happens when preparation meets opportunity.

There's no better example of that than a 2016 discovery at the University of California, Irvine, by doctoral student Mya Le Thai. After playing around in the lab, she made a discovery that could lead to a rechargeable battery that could last up to 400 years. That means longer-lasting laptops and smartphones and fewer lithium ion batteries piling up in landfills.

Keep ReadingShow less
@caitlin.the.realtor/TikTok, used with permission

Wait, so 90's fashion is in, but 90's hair is out?

Every era has its own version of what’s attractive. And very rarely does that aesthetic hold power with the following generation. In fact, it often becomes the opposite of cool.

Just think of Elvis. He might have been a universal sex symbol for a time, but it also wasn’t long before his pompadour became passé. Same goes for Paul Newman’s rugged manliness, David Cassidy’s babyface, Tom Selleck’s mustache. Indeed, for everything a season.

Which brings us to the 90s. The age of beach blonde surfer boys (real surfing skills not required, but a plus). Of flannel, lots of flannel, and super chiseled bodies. Let’s not forget this was the dawning of the term “metrosexual,” and also the time period that brought us that Calvin Klein ad with Mark Wahlburg.

How exactly would these guys measure up with the Gen Z kids today?

Keep ReadingShow less

A Eurasian crow.

A family from Denmark has created a touching video montage documenting their unique friendship with a wild Eurasian crow. This crow, affectionately named Russell, has become an honorary member of their household, forming special bonds with each family member, including the pets.

However, the crow's relationship with their son, 2-year-old Otto, is truly extraordinary. “They could spend hours just playing,” Otto’s mother, Laerke Luna, says in a video shared by The Dodo. "When Otto is outside, he will never leave Otto’s side.”

Russell, the free-spirited crow, ventures away from the family's home from time to time, but never for too long. He always comes back and announces his return by tapping on the door, swooping in to lounge on the sofa, or awaiting Otto's return from school atop their roof.

“When we are inside, he will sit inside the window because he wants Otto to go outside with him,” Laerke said.

The family’s relationship with Russell didn’t come out of nowhere. When Russell was a young bird, he had health problems so the family took him and nursed the bird back to health. Eventually, they witnessed his first attempts to fly.

Recently, Russell became friends with another family member, their second child, Hedwig. Although he does get a little annoyed with the bird’s frequent attempts to nab his pacifier.

Even though it’s rare for humans to strike up such a close bond with a crow, according to research, it’s not that surprising. Audubon says that crows are “some of the smartest animals in the world” with an intelligence “on par with chimpanzees.” They are also very social and family-oriented, so no wonder Russell loves Otto and his family.

Crow Named Russell Waits For His Favorite Kid To Get Home From School | The Dodo


Learning

Why you shouldn't throw your dishwasher pod into the bottom of your dishwasher

Dishwashers actually use the dirty water to know how to wash your dishes.

Photos by cottonbro studio and PhotoMIX Ltd. via Canva

Why your detergent shouldn't go in the bottom of the dishwasher

There always seem to be something going on with the pods and powders you're supposed to use in the dishwasher to clean your dishes. Either the pods don't dissolve completely or the powder gets all goopy and hard, never really fully dispensing into the dishwasher.

The inconsistency in product dispensing can leave you wondering if the dishes are even getting cleaned, causing some to toss the detergent pod into the bottom of the dishwasher. It would seem that placing the detergent at the bottom would allow for it to actually reach your dirty dishes. But Melissa Pateras, a domestic expert, explains that doing it that way isn't doing what you think it's doing.

Pateras actually breaks down exactly how dishwashers work to clean your dishes while explaining why putting the detergent on the bottom is ineffective.

Keep ReadingShow less