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Carter and his wife celebrated a record low in cases last year.

“Rosalynn and I are pleased with this continued advance toward eradicating Guinea worm disease,” President Carter said. “Our partners, especially those in the affected villages, work with us daily to rid the world of this scourge. We are heartened that eradication can be achieved soon.”

After Carter left the White House in 1981, he went on a mission to fight “neglected” diseases in far-off places that most Americans would never have to worry about. He set his sights on conditions such as lymphatic filariasis, trachoma, river blindness, and schistosomiasis.

His former drug czar Peter Borne brought Guinea worm to his attention. Borne approached the Carter Center because no one else would touch the problem.

Guinea worm is also known as dracunculiasis which means “affliction with little dragons” in Latin. About a year after infection, the worms grow to three feet long, and the females prepare to give birth by making their way to a place right below the skin, causing painful blisters.

Eventually, the blisters burst and the mother burrows her way out, causing incredible pain.

To ease the pain, people often submerge the affected area in water, causing tens of thousands of baby worms to release in the water, where they will eventually find a host. Guinea worm can also cause fever, swelling and secondary infections like sepsis. Guinea worm causes significant hardships for families by rendering people unable to work or attend school.

“It’s an audacious and mind-boggling idea,” said Emily Staub, press liaison to health programs for the Carter Center, according to CNN. “I’m not just talking about just him. I’m talking about a whole bunch of people with the Carter Center that decided that they were going to eradicate a disease that has no vaccine, no immunity, no medication. It’s thousands of years old and has a one-year incubation. The odds are totally stacked against you. And the people that suffer from it speak thousands of different languages, and some have never had outsiders interact with them.”

But Carter persisted, creating countless partnerships with leaders around the globe to educate people about the worm, provide tools for clean water and prevent its spread in the animal population. "Guinea worm disease has no cure, no vaccination, basically the entire eradication effort is built on behavior change,” Kelly Callahan, a public health worker who partnered with the Carter Center, told NPR.

Thirty-seven years after the Carter Center started on the audacious task of eradicating Guinea worm, the WHO has certified that 200 countries are free of the disease, meaning they've had zero instances of transmission in three years. Only six countries have yet to be certified as disease-free.

Jimmy Carter set a nearly impossible task, but with dogged persistence and the ability to make partnerships with people worldwide, many of whom have had little contact with the outside, he has helped save millions upon millions of people from incredible suffering.

In the coming days, people will celebrate many of Carter’s accomplishments. Let’s be sure that no one forgets to mention a success he’d rank among his proudest.

“We were traveling in a big motorcade,” he said in 2017. “We were driving along, and elementary school children had a big sign that says, ‘Watch out, Guinea worm. Here comes Jimmy Carter.’ That was almost as good as a Nobel Prize for me.”